Results 11 to 20 of about 130,186 (296)
Controls for Immunocytochemistry [PDF]
Immunocytochemistry is a highly productive method in biomedical research used to identify proteins and other macromolecules in tissues and cells. Control samples are required to show label localization is correct, but the understanding and use of ...
Richard W. Burry
core +3 more sources
Developmentally Guided Differentiation of Ventral Midbrain Dopaminergic Cells Validated in Proteopathy-Based Parkinson's Disease Models. [PDF]
A developmentally guided protocol reproducibly specifies EN1‐positive ventral midbrain dopaminergic (vmDA) progenitors from human pluripotent stem cells and yields functional vmDA neurons. Optogenetic induction of α‐synuclein aggregation elicits selective degeneration of TH‐positive neurons in 2D cultures and 3D neurospheroids, while transplanted ...
Moon H +12 more
europepmc +2 more sources
Inflammatory fibroid polyps (IFPs) tend to occur in the gastrointestinal tract, and they are rare and benign neoplasms. In general, IFPs often come from epithelial tissue. The gastric antrum is the most common location.
Wang Huan +4 more
doaj +1 more source
Objective: Determination of the molecular status is mandatory for personalized treatment of patients with non-small cell lung carcinoma. The present study was performed to detect anaplastic lymphoma kinase (ALK) rearrangements in pulmonary adenocarcinoma
Suneel RACHAGIRI +5 more
doaj +1 more source
Detection of bone marrow disseminated tumor cells in micrometastasis of breast cancer
Objective To explore the sensitive immunocytochemical assay for disseminated tumor cells(DTC) in bone marrow of breast cancer patients. Methods First, the human breast cancer cell line MCF-7 was used as the specimen, and a mature immunocytochemical ...
YU Zi-yi +5 more
doaj +1 more source
The medial prefrontal cortex (mPFC) exerts top-down control of primary visual cortex (V1) activity. As there is no direct neuronal projection from mPFC to V1, this functional connection may use an indirect route, i.e., via basalo-cortical cholinergic ...
Hoang Nam eNguyen +2 more
doaj +1 more source
Calretinin Immunoreactivity in the VIIIth Nerve and Inner Ear Endorgans of Ranid Frogs
Calcium-binding proteins are essential for buffering intracellular calcium concentrations, which are critical for regulating cellular processes involved in neuronal computations. One such calcium-binding protein, calretinin, is present in many neurons of
Ingrid Reichenberger +2 more
doaj +1 more source
Expression of p63 and Bcl-2 in Malignant Thyroid Tumors and their Correlation with other Diagnostic Immunocytochemical Markers [PDF]
Introduction: Bcl-2 is a marker recently studied in thyroid tumours and proposed to have prognostic significance. p63 is expressed in a proportion of papillary thyroid carcinoma cases and may have a role in tumour progression.
Ashumi Gupta +3 more
doaj +1 more source
During apoptosis, the nuclear enzyme Poly(ADPRibose) Polymerase-1 (PARP-1) catalyzes the rapid and transient synthesis of poly(ADP-ribose) from NAD+ and becomes inactive when cleaved by caspases.
C Soldani +3 more
doaj +1 more source

