Results 11 to 20 of about 2,944 (176)

Spatial transcriptomic analysis across histological subtypes reveals molecular heterogeneity and prognostic markers in early‐stage lung adenocarcinoma

Clinical and Translational Medicine
Background The progression and prognosis of early‐stage lung adenocarcinoma are closely associated with histologic subtypes, yet the presence of mixed histologic patterns often complicates prognostic assessment.
Hua Geng, Wenhao Zhou, Haitao Luo, Jiaqian Wang, Shixiong Li, Congcong Song, Yujie Zhao, Meilin Xu   +7 more
doaj   +2 more sources

Bioinformatics-Driven Design of Fusion Recombinant Protein (EgFABP1-EgTeg) for Enhanced Immunodiagnosis of Hydatid Cysts. [PDF]

Immun Inflamm Dis
ABSTRACT Background Hydatid cyst disease is caused by the parasite Echinococcus and poses significant health concerns worldwide. Due to the lack of early symptoms and limited diagnostic tools, researchers aim to design a more specific and sensitive antigen. The study focuses on developing a recombinant multi‐epitope antigen using two parasite proteins (
Mehdi AMK, Motedayyen H, Arbabi M, Hasan-Abad AM.   +3 more
europepmc   +2 more sources

The Role of Innate Lymphoid Cells in the Pathogenesis of Hepatic Echinococcosis: A Literature Review. [PDF]

Parasite Immunol
ABSTRACT Hepatic echinococcosis (HE), a major zoonotic disease, remains endemic in pastoral regions of Western China, where its incidence is closely linked to geographical, livestock and sanitary conditions. The disease presents a significant clinical challenge due to the complexity of host–parasite interactions and a high recurrence rate. To date, the
Ma W, Wang D, Liu C, Fan H.
europepmc   +2 more sources

The Efficiency of Commercial Immunodiagnostic Assays for the Field Detection of Schistosoma japonicum Human Infections: A Meta-Analysis

Pathogens, 2022
Although great strides have been achieved, schistosomiasis japonica remains a major public health concern in China. Immunodiagnostics have been widely accepted as the first choice in large-scale screening of Schistosoma japonicum human infections, and ...
Zhongqiu Mei, Shan Lv, Liguang Tian, Wei Wang, Tiewu Jia   +4 more
doaj   +1 more source

IMMUNODIAGNOSIS IN MEMBRANOUS NEPHROPATHY

Wiadomości Lekarskie, 2020
One of the diseases leading to chronic end-stage renal disease is membranous nephropathy (MN). The main cause of this disease is the formation of antibodies to foreign and native antigens. Membranous nephropathy can be conventionally divided into 2 types: primary form (when the primary disease is unknown) and secondary form.
Magdalena, Ratajczak, Ewa, Poleszak, Tomasz, Chrościcki   +2 more
openaire   +3 more sources

Diagnostic Performance of Parasitological, Immunological, Molecular, and Ultrasonographic Tests in Diagnosing Intestinal Schistosomiasis in Fieldworkers From Endemic Municipalities in the Philippines

Frontiers in Immunology, 2022
Schistosomiasis remains to ha/ve a significant public health impact in the Philippines. The Kato-Katz (K-K) technique is the reference standard and most used technique for definitive diagnosis of intestinal schistosomiasis for control programs in endemic
Ian Kim B. Tabios, Ian Kim B. Tabios, Ian Kim B. Tabios, Marcello Otake Sato, Ourlad Alzeus G. Tantengco, Raffy Jay C. Fornillos, Masashi Kirinoki, Megumi Sato, Raniv D. Rojo, Ian Kendrich C. Fontanilla, Yuichi Chigusa, Paul Mark B. Medina, Mihoko Kikuchi, Lydia R. Leonardo, Lydia R. Leonardo, Lydia R. Leonardo, Lydia R. Leonardo   +16 more
doaj   +1 more source

Multi‐omics analyses reveal spatial heterogeneity in primary and metastatic oesophageal squamous cell carcinoma

Clinical and Translational Medicine, Volume 13, Issue 11, November 2023., 2023
Our study comprehensively characterised spatial intra‐tumoral heterogeneity (ITH) in ESCC by multi‐omics analyses of the superficial and deep subregions of the primary tumour and matched lymph node metastasis (LNmet). Spatial segmentation through digital spatial profiling was used to explore ITH. Differential molecular profiles were observed across the
Haitao Huang, Na Li, Yingkuan Liang, Rutao Li, Xing Tong, Jinyuan Xiao, Hongzhen Tang, Dong Jiang, Kai Xie, Chen Fang, Shaomu Chen, Guangbin Li, Bin Wang, Jiaqian Wang, Haitao Luo, Lingchuan Guo, Haitao Ma, Wei Jiang, Yu Feng   +18 more
wiley   +1 more source

Dense fine speckled nuclear immunofluorescence: A mildly reassuring antinuclear antibody pattern meriting consideration

Immunity, Inflammation and Disease, Volume 11, Issue 9, September 2023., 2023
The hallmark of autoimmune connective tissue diseases is the production of many different circulating antinuclear antibodies. A newly emphasized antinuclear antibody with its dense fine speckled nuclear immunofluorescence pattern may constitute a differentiating factor, with an anti‐DFS70 antibody assay distinguishing healthy people and autoimmune ...
Aleksandra Fijałkowska, Robert A. Schwartz, Anna Woźniacka   +2 more
wiley   +1 more source

A lateral flow assay for the immunodiagnosis of human cat‐transmitted sporotrichosis

Mycoses, Volume 65, Issue 10, Page 926-934, October 2022., 2022
Abstract Background Cat‐transmitted sporotrichosis (CTS) caused by Sporothrix brasiliensis has emerged as an important zoonosis in Brazil and neighbouring countries. Objectives Evaluate the performance of a lateral flow assay (LFA) for the detection of anti‐Sporothrix antibodies in human sera.
Regielly Cognialli, Konner Bloss, Izabella Weiss, Diego H. Caceres, Rachelle Davis, Flavio Queiroz‐Telles   +5 more
wiley   +1 more source

Imunodiagnóstico Immunodiagnosis

Memorias do Instituto Oswaldo Cruz, 1992
In the last years, the knowledge about immunodiagnosis in schistosomiasis has increased considerably. This was due to a better immunologic understanding of the host-parasite interaction and the evolution of the technical procedures by the introduction of
Silvia Maria Lucena Montenegro
doaj   +1 more source