Results 21 to 30 of about 12,907 (305)

Stability Assessment of Four Chimeric Proteins for Human Chagas Disease Immunodiagnosis

open access: yesBiosensors, 2021
The performance of an immunoassay relies on antigen-antibody interaction; hence, antigen chemical stability and structural integrity are paramount for an efficient assay.
P. F. Celedon   +9 more
semanticscholar   +1 more source

Proof of Concept of a Novel Multiepitope Recombinant Protein for the Serodiagnosis of Patients with Chagas Disease

open access: yesPathogens, 2023
Chagas disease remains a neglected disease that is considered to be a public health problem. The early diagnosis of cases is important to improve the prognosis of infected patients and prevent transmission.
Juliana Martins Machado   +19 more
doaj   +1 more source

The Efficiency of Commercial Immunodiagnostic Assays for the Field Detection of Schistosoma japonicum Human Infections: A Meta-Analysis

open access: yesPathogens, 2022
Although great strides have been achieved, schistosomiasis japonica remains a major public health concern in China. Immunodiagnostics have been widely accepted as the first choice in large-scale screening of Schistosoma japonicum human infections, and ...
Zhongqiu Mei   +4 more
doaj   +1 more source

Multi‐omics analyses reveal spatial heterogeneity in primary and metastatic oesophageal squamous cell carcinoma

open access: yesClinical and Translational Medicine, Volume 13, Issue 11, November 2023., 2023
Our study comprehensively characterised spatial intra‐tumoral heterogeneity (ITH) in ESCC by multi‐omics analyses of the superficial and deep subregions of the primary tumour and matched lymph node metastasis (LNmet). Spatial segmentation through digital spatial profiling was used to explore ITH. Differential molecular profiles were observed across the
Haitao Huang   +18 more
wiley   +1 more source

Diagnostic Performance of Parasitological, Immunological, Molecular, and Ultrasonographic Tests in Diagnosing Intestinal Schistosomiasis in Fieldworkers From Endemic Municipalities in the Philippines

open access: yesFrontiers in Immunology, 2022
Schistosomiasis remains to ha/ve a significant public health impact in the Philippines. The Kato-Katz (K-K) technique is the reference standard and most used technique for definitive diagnosis of intestinal schistosomiasis for control programs in endemic
Ian Kim B. Tabios   +16 more
doaj   +1 more source

Dense fine speckled nuclear immunofluorescence: A mildly reassuring antinuclear antibody pattern meriting consideration

open access: yesImmunity, Inflammation and Disease, Volume 11, Issue 9, September 2023., 2023
The hallmark of autoimmune connective tissue diseases is the production of many different circulating antinuclear antibodies. A newly emphasized antinuclear antibody with its dense fine speckled nuclear immunofluorescence pattern may constitute a differentiating factor, with an anti‐DFS70 antibody assay distinguishing healthy people and autoimmune ...
Aleksandra Fijałkowska   +2 more
wiley   +1 more source

IMMUNODIAGNOSIS IN MEMBRANOUS NEPHROPATHY

open access: yesWiadomości Lekarskie, 2020
One of the diseases leading to chronic end-stage renal disease is membranous nephropathy (MN). The main cause of this disease is the formation of antibodies to foreign and native antigens. Membranous nephropathy can be conventionally divided into 2 types: primary form (when the primary disease is unknown) and secondary form.
Magdalena, Ratajczak   +2 more
openaire   +3 more sources

Seroprevalence of toxocariasis in children aged 1-9 years in western Islamic Republic of Iran, 2003 [PDF]

open access: yes, 2007
We determined the seroprevalence of Toxocara canis infection in 544 children under 10 years randomly selected from urban and rural areas of Hamadan, An enzyme-linked immunosorbent assay was used for detection of antibodies to T.
Azimi, A., Fallah, M., Taherkhani, H.
core   +1 more source

Serum Autoantibodies against LRDD, STC1, and FOXA1 as Biomarkers in the Detection of Ovarian Cancer

open access: yesDisease Markers, Volume 2022, Issue 1, 2022., 2022
Purpose. This study is aimed at evaluating serum autoantibodies against four tumor‐associated antigens, including LRDD, STC1, FOXA1, and EDNRB, as biomarkers in the immunodiagnosis of ovarian cancer (OC). Methods. The autoantibodies against LRDD, STC1, FOXA1, and EDNRB were measured using an enzyme‐linked immunosorbent assay (ELISA) in 94 OC patients ...
Yaru Duan   +9 more
wiley   +1 more source

Clinical Significance of Negative Costimulatory Molecule PD‐1/PD‐L1 on Peripheral Blood Regulatory T Cell Levels among Patients with Pulmonary Tuberculosis

open access: yesJournal of Tropical Medicine, Volume 2022, Issue 1, 2022., 2022
Objective. This study aimed to investigate the expression and clinical significance of negative costimulatory molecules programmed death‐1 (PD‐1) and programmed death ligand 1 (PD‐L1) on CD4+CD25+CD127low regulatory T cells (Tregs) in peripheral blood of patients with active pulmonary tuberculosis (TB). Methods.
Chenchen Yang   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy