Immunodiagnostic profiling of SPON2 and MSMB as biomarkers in prostate cancer for nanomaterial- based detection strategies [PDF]
Frontiers in ImmunologyBackgroundThis study aimed to validate secreted biomarkers SPON2 and MSMB with tumor-specific expression and immunogenicity for nanomaterial-based prostate cancer diagnostics.MethodsGene expression data (GSE55945), comprising 13 prostate tumor and 8 ...
Jianzeng Ye +4 more
doaj +2 more sources
Performance of Immunodiagnostic Tests for Typhoid Fever: A Systematic Review and Meta-Analysis
Pathogens, 2021 Typhoid fever, also known as typhoid, is a life-threatening bacterial infection that remains a global health concern. The infection is associated with a significant morbidity and mortality rate, resulting in an urgent need for specific and rapid ...
Mohamad Ahmad Najib +11 more
doaj +3 more sources
Sensitivity of Immunodiagnostic Tests in Localized Versus Disseminated Tuberculosis—A Systematic Review of Individual Patient Data [PDF]
Tropical Medicine and Infectious DiseaseOur objective was to perform a systematic review of individual patient data comparing immunodiagnostic test sensitivity in patients with localized versus disseminated tuberculosis who are from high- and less-than-high-income countries.
Michael Eisenhut +7 more
doaj +2 more sources
Agronomy, 2018 Sugarcane mosaic virus (SCMV) is a mosaic disease that has spread over sugarcane plantations in Indonesia. The important step to overcome the disease is to detect the pathogen as early as possible.
Nurmalasari Darsono +6 more
doaj +3 more sources
A novel autoantibody signatures for enhanced clinical diagnosis of pancreatic ductal adenocarcinoma [PDF]
Cancer Cell International, 2023 Background Pancreatic ductal adenocarcinoma (PDAC) is a devastating disease that requires precise diagnosis for effective treatment. However, the diagnostic value of carbohydrate antigen 19 − 9 (CA19-9) is limited.
Tiandong Li +9 more
doaj +2 more sources
PLoS Neglected Tropical Diseases, 2013 BackgroundThe diagnosis of Human African Trypanosomiasis relies mainly on the Card Agglutination Test for Trypanosomiasis (CATT). While this test is successful, it is acknowledged that there may be room for improvement. Our aim was to develop a prototype
Lauren Sullivan +3 more
doaj +2 more sources
Biomolecules, 2023 Stress-induced myocardial perfusion defects found in dipyridamole–thallium-201 single-photon emission computed tomography imaging may indicate vascular perfusion abnormalities and risk of obstructive or nonobstructive coronary heart disease.
Yu-Chieh Chang +5 more
doaj +1 more source
Shark IgNAR: The Next Broad Application Antibody in Clinical Diagnoses and Tumor Therapies?
Marine Drugs, 2023 Antibodies represent a relatively mature detection means and serve as therapeutic drug carriers in the clinical diagnosis and treatment of cancer—among which monoclonal antibodies (mAbs) currently occupy a dominant position.
Xiaofeng Jiang +5 more
doaj +1 more source
Capture ELISA for KPC Detection in Gram-Negative Bacilli: Development and Standardisation
Microorganisms, 2023 The detection of KPC-type carbapenemases is necessary for guiding appropriate antibiotic therapy and the implementation of antimicrobial stewardship and infection control measures.
André Valencio +6 more
doaj +1 more source
STANDARDIZATION OF THE PROTEIN CALIBRATORS ISOLATION METHODOLOGY FOR THROMBOPHILIA MARKERS DETECTING IMMUNODIAGNOSTIC TEST SYSTEMS [PDF]
Biotechnologia Acta, 2022 The most accurate laboratory methods for thrombophilia diagnostics are based on the quantitative determination of the blood plasma specific markers that appear as a result of the coagulation cascade activation.
Daria Korolova +5 more
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