Detection of antibodies against Leishmania species using enzyme-linked immunosorbent assay in cats from the western border of Brazil [PDF]
: Feline leishmaniosis is infrequent worldwide, and cats have been suggested as secondary reservoirs for the parasite. However, specific diagnostic techniques for feline samples are scarce.
Gabriela Döwich Pradella +8 more
doaj +1 more source
Rapid development of neutralizing and diagnostic SARS-COV-2 mouse monoclonal antibodies
The need for high-affinity, SARS-CoV-2-specific monoclonal antibodies (mAbs) is critical in the face of the global COVID-19 pandemic, as such reagents can have important diagnostic, research, and therapeutic applications.
Asheley P. Chapman +21 more
doaj +1 more source
RationaleTuberculosis diagnosis in children remains challenging. Microbiological confirmation of tuberculosis disease is often lacking, and standard immunodiagnostic including the tuberculin skin test and interferon-γ release assay for tuberculosis ...
Noëmi Rebecca Meier +9 more
doaj +1 more source
Predictive biomarkers for checkpoint inhibitor-based immunotherapy: The Galectin-3 signature in NSCLCs [PDF]
Checkpoint inhibitor-based immunotherapy is opening a promising scenario in oncology, with objective responses registered in multiple cancer types. However, reliable predictive markers of tumor responsiveness are still lacking.
Bartolazzi A. +4 more
core +1 more source
Antibody responses to Sarcoptes scabiei apolipoprotein in a porcine model: relevance to immunodiagnosis of recent infection. [PDF]
No commercial immunodiagnostic tests for human scabies are currently available, and existing animal tests are not sufficiently sensitive. The recombinant Sarcoptes scabiei apolipoprotein antigen Sar s 14.3 is a promising immunodiagnostic, eliciting high ...
Melanie Rampton +7 more
doaj +1 more source
In point-of-care testing (POCT), tests are performed near patients and results are given rapidly for timely clinical decisions. Immunodiagnostic assays are one of the most important analyses for detecting and quantifying protein-based biomarkers. However,
Xuyang Hu +4 more
doaj +1 more source
The relationship between the insulin-like growth factor-1 axis, weight loss, an inflammation-based score and survival in patients with inoperable non-small cell lung cancer [PDF]
<b>Background & aims:</b> The involvement of a systemic inflammatory response, as evidenced by the Glasgow Prognostic Score (GPS), is associated with weight loss and poor outcome in patients with non-small cell lung cancer.
Forrest, L.M. +3 more
core +1 more source
The Role of Immunosenescence in Neurodegenerative Diseases
Aging is characterized by the progressive decline of physiological function and tissue homeostasis leading to increased vulnerability, degeneration, and death.
Erica Costantini +2 more
doaj +1 more source
Towards pain-free diagnosis of skin diseases through multiplexed microneedles: biomarker extraction and detection using a highly sensitive blotting method [PDF]
Immunodiagnostic microneedles provide a novel way to extract protein biomarkers from the skin in a minimally invasive manner for analysis in vitro.
A Bhargav +28 more
core +2 more sources
Isolated deficiency of IgE in humans: update
Isolated deficiency IgE is one of the most common primary immunodeficiency diseases in human with prevalence of 1 case per 30 people of total population.
D.V. Maltsev, I.R. Rybak, V.Yu. Gorbenko
doaj +1 more source

