Results 21 to 30 of about 8,528 (179)

The Role of Immunosenescence in Neurodegenerative Diseases

Mediators of Inflammation, 2018
Aging is characterized by the progressive decline of physiological function and tissue homeostasis leading to increased vulnerability, degeneration, and death.
Erica Costantini, Chiara D’Angelo, Marcella Reale   +2 more
doaj   +1 more source

Isolated deficiency of IgE in humans: update

Aktualʹnaâ Infektologiâ, 2017
Isolated deficiency IgE is one of the most common primary immunodeficiency diseases in human with prevalence of 1 case per 30 people of total population.
D.V. Maltsev, I.R. Rybak, V.Yu. Gorbenko
doaj   +1 more source

Point-of-Care Diagnostics: Recent Advances and Trends

Biosensors, 2017
Recent years have witnessed tremendous advances in point-of-care diagnostics (POCD), which are a result of continuous developments in biosensors, microfluidic, bioanalytical platforms, assay formats, lab-on-a-chip technologies, and complementary ...
Sandeep Kumar Vashist
doaj   +1 more source

Comparison of Antigen Conjugation to a Peptidic Carrier or to Bovine Serum Albumin in the Serodiagnosis of Canine Visceral Leishmaniasis via Suspension Array Technology

Antibodies
Backgroud/Objectives: Canine Visceral Leishmaniasis (CVL), caused by Leishmania infantum, is a significant public health concern due to dogs serving as reservoirs for human infection. An accurate and rapid diagnostic method to distinguish symptomatic and
Thais Stelzer Toledo, Pauline Martins Cunha, Josué da Costa Lima-Junior, Monique Paiva De Campos, Alinne R. S. Renzetti, Fabiano Borges Figueiredo, Fernanda Nazaré Morgado, Renato Porrozzi, Fatima da Conceição-Silva, Marta de Almeida Santiago, Paula Mello De Luca   +10 more
doaj   +1 more source

A 3D Human Bone and Bone Marrow‐on‐a‐Chip Model for In Vitro Bone Remodeling and Immune Cell Maintenance

Advanced Science, EarlyView.
This study presents a human Bone (and Bone Marrow)‐on‐a‐Chip model based on native human bone scaffolds and autologous cells. Dynamic perfusion and sequential cell seeding replicate the physiological bone remodeling process in vitro, enabling the long‐term culture of functional, mature bone marrow immune subpopulations.
Nina Stelzer, Melanie‐Jasmin Ort, Kristian Händler, Emely Bortel, Ioanna Maria Dimitriou, Martin Textor, Georg N. Duda, Janosch Schoon, Uwe Marx, Uwe Kornak, Annika Winter, Bernhard Hesse, Stefanie Donner, Sebastian Hardt, Oliver Klein, Simon Reinke, Malte Spielmann, Sven Geißler   +17 more
wiley   +1 more source

Serodiagnosis of urogenital schistosomiasis and profiling of immunoreactive protein(s) in Schistosoma haematobium soluble egg and adult worm antigens

Journal of Vector Borne Diseases
Background & objectives: To achieve schistosomiasis eradication plan by 2030, the development of efficient diagnosis is crucial. This study focuses on assessing the immunodiagnostic potential of S.
Kabirat A Sulaiman, Tajudeen O Oriade, Timothy Auta, Funmilayo I D Afolayan, Alexander B Odaibo, Rafaella FQ Grenfell, Ramzy G Fatem, Oyetunde T Oyeyemi   +7 more
doaj   +1 more source

Left ventricular diastolic dysfunction worsens prognosis in patients with heart failure due to dilated cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 1183-1193, April 2025.
Abstract Aims The prognostic significance of left ventricular (LV) diastolic dysfunction (LVDD) severity in patients with dilated cardiomyopathy (DCM) remains uncertain. This study aimed to evaluate the association of LVDD severity and elevated left atrial pressure (eLAP) with patient outcomes in stable, non‐acutely decompensated patients with DCM ...
Mateusz Winiarczyk, Ewa Dziewięcka, Sylwia Wiśniowska‐Śmiałek, Agnieszka Stępień, Katarzyna Graczyk, Agata Leśniak‐Sobelga, Marta Hlawaty, Jakub Woźniak, Maryia Savitskaya, Katarzyna Holcman, Magdalena Kostkiewicz, Piotr Podolec, Paweł Rubiś   +12 more
wiley   +1 more source

A Perspective on the Role of Point-of-Care “Immuno-Triaging” to Optimize COVID-19 Vaccination Distribution in a Time of Scarcity

Frontiers in Public Health, 2021
Vaccine bears hope to bring COVID-19 pandemic under control. With limited supply, vaccines must be utilized efficiently to provide protection to those who need it most. Currently, no practical framework has been proposed to ensure fair vaccine allocation
Yi Zhang, Yi Zhang, Angela Rogers, Kari Nadeau, Jun Gu, Samuel Yang   +5 more
doaj   +1 more source

Prevalence of insulin dysregulation in a sport horse population as determined by traditional and stall‐side testing

Equine Veterinary Journal, EarlyView.
Abstract Background The prevalence of insulin dysregulation (ID) has not been investigated in sport horses. Stall‐side insulin assays offer convenience but need further validation. Objectives To determine the prevalence of and risk factors for ID in a sport horse population using an oral sugar test (OST) and assess agreement between stall‐side and ...
Kimberly L. Hallowell, Caitlyn R. Horne, Cary S. Miller, Sara R. Tufts, Katarzyna Dembek, Kim R. Love, Andrew W. van Eps, Lauren V. Schnabel   +7 more
wiley   +1 more source

Development of Anti-Yersinia pestis Human Antibodies with Features Required for Diagnostic and Therapeutic Applications

ImmunoTargets and Therapy, 2020
Antonietta M Lillo,1 Nileena Velappan,1 Julia M Kelliher,1 Austin J Watts,1 Samuel P Merriman,1 Grace Vuyisich,2 Laura M Lilley,2 Kent E Coombs,1 Tara Mastren,2 Munehiro Teshima,1 Benjamin W Stein,2 Gregory L Wagner,2 Srinivas Iyer,1 Andrew RM Bradbury,3
Lillo AM, Velappan N, Kelliher JM, Watts AJ, Merriman SP, Vuyisich G, Lilley LM, Coombs KE, Mastren T, Teshima M, Stein BW, Wagner GL, Iyer S, Bradbury ARM, Harris JF, Dichosa AE, Kozimor SA   +16 more
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