Imunodiagnóstico Immunodiagnosis
In the last years, the knowledge about immunodiagnosis in schistosomiasis has increased considerably. This was due to a better immunologic understanding of the host-parasite interaction and the evolution of the technical procedures by the introduction of
Silvia Maria Lucena Montenegro
doaj +1 more source
Development of a one-step probe based molecular assay for rapid immunodiagnosis of infection with M. tuberculosis using dried blood spots. [PDF]
BACKGROUND:Antigen specific release of IP-10 is the most promising alternative marker to IFN-γ for infection with M. tuberculosis. Compared to Interferon-γ release assays (IGRA), IP-10 is released in high levels enabling novel approaches such as field ...
Thomas Blauenfeldt +12 more
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A Circadian Trough in Glucocorticoid Signaling Is Essential for Bone Health in Mice
Flattening the circadian rhythm of endogenous glucocorticoids induces osteoporosis in mice. We demonstrate that reinstating a trough in glucocorticoid receptor signaling stimulates bone formation and suffices to prevent osteoporosis. Reinstating the trough at its natural time of day is needed for full protection.
Annelies E. Smit +9 more
wiley +1 more source
Features Immunodiagnostic Local Forms of Tuberculosis in Children
The 100 children with local forms of tuberculosis (LFT) were examinated used by the method of continuous sampling. The results of the LFT immunodiagnostic with the Diaskintest (DST) in the children were evaluated.
E. A. Borodulina +5 more
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Comparison of the Prognostic Value of Three Different Single HLA Based Antibody Detection Assays
ABSTRACT Single antigen (SA) tests are indispensable for an accurate HLA antibody identification in sera of transplant patients. Three commercial tests using purified single antigens combined with microbead or microarray technology are currently available. This study aims to determine the prognostic value of these tests prior to kidney transplantation.
Falko M. Heinemann +29 more
wiley +1 more source
Hybridoma technique and monoclonal antibodies for mariculture applications [PDF]
Ever since the beginnings of experimental immunology at the end of the nineteenth century, scientists have exploited the specificity of antibodies to detect, isolate and analyze biological material.
Sobhana, K S
core
Expression-Based Genome-Wide Association Study Links Vitamin D-Binding Protein With Autoantigenicity in Type 1 Diabetes. [PDF]
Type 1 diabetes (T1D) is caused by autoreactive T cells that recognize pancreatic islet antigens and destroy insulin-producing β-cells. This attack results from a breakdown in tolerance for self-antigens, which is controlled by ectopic antigen expression
Butte, Atul J +9 more
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To aid the clinical diagnosis of typhoid fever in India, where most hospitals and primary health centres have no facilities for culture, we report on the development of a novel and rapid immunodiagnostic kit for the direct detection of Salmonella Typhi ...
Rahul Mitra +4 more
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MARPLE: A Proximity‐Triggered CRISPR‐Cas13 Platform for Ultrasensitive Antibody Detection
MARPLE is a modular CRISPR‐Cas13 immunoassay that uses antibody‐induced proximity to trigger a toehold‐exchange reaction, releasing an RNA activator for Cas13. This one‐pot, isothermal architecture enables ultrasensitive (femtomolar) and highly specific detection of diverse antibodies, including therapeutic, pathogen‐specific, and cancer‐associated ...
Elena Spezzani +6 more
wiley +1 more source
Establishing reference intervals for bone turnover markers in healthy postmenopausal women in a nonfasting state. [PDF]
In order to interpret bone turnover markers (BTMs), we need to establish healthy reference intervals. It is difficult to establish reference intervals for older women because they commonly suffer from diseases or take medications that affect bone ...
Eastell, R. +7 more
core +1 more source

