Results 111 to 120 of about 1,052,494 (379)

Syncrip/hnRNP Q is required for activity-induced Msp300/Nesprin-1 expression and new synapse formation. [PDF]

, 2019
Memory and learning involve activity-driven expression of proteins and cytoskeletal reorganization at new synapses, requiring posttranscriptional regulation of localized mRNA a long distance from corresponding nuclei.
Davis, Ilan, Gratton, Enrico, Ish-Horowicz, David, Järvelin, Aino, Robertson, Francesca, Smith, Carlas, Titlow, Joshua   +6 more
core   +4 more sources

Direct Immunofluorescence in Oral Lichen Planus.

Journal of clinical and diagnostic research : JCDR, 2015
INTRODUCTION Oral lichen planus (OLP) is a common immune-mediated oral mucosal disease. Diagnosis of OLP depends mainly on both clinical and histopathological features.
W. Buajeeb, Nis Okuma, S. Thanakun, Titikarn Laothumthut   +3 more
semanticscholar   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Immunofluorescence in dermatology

Indian Journal of Dermatology, Venereology, and Leprology, 2012
Direct immunofluorescence (DIF) and indirect immunofluorescence (IIF) tests on skin biopsy are being done mostly in academic teaching hospitals. These tests provide a useful diagnostic aid to dermatologists. Immunohistology and serology can, in conjunction with histology, provide considerable help in delineation and diagnosis of various skin disorders ...
Seema, Chhabra, Ranjana Walker, Minz, Biman, Saikia   +2 more
openaire   +2 more sources

Copy number variations in healthy subjects. Case study: iPSC line CSSi005-A (3544) production from an individual with variation in 15q13.3 chromosome duplicating gene CHRNA7 [PDF]

, 2018
CHRNA7, encoding the neuronal alpha7 nicotinic acetylcholine receptor (a7nAChR), is highly expressed in the brain, particularly in the hippocampus. It is situated in the 15q13.3 chromosome region, frequently associated with a Copy Number Variation (CNV),
Altieri, Filomena, Bernardini, Laura, Della Monica, Matteo, Ferrari, Daniela, Goldoni, Marina, Lamorte, Giuseppe, Mazzoccoli, Gianluigi, Postorivo, Diana, Rosati, Jessica, Tata, Ada Maria, Torres, Barbara, Turco, Elisa Maria, Vescovi, Angelo Luigi, Vinci, Ersilia   +13 more
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Immunostaining and Ciliary Movement Analysis in Primary Ciliary Dyskinesia With a Homozygous Deletion Involving Exons 1–4 of DRC1: A Case Report

Respirology Case Reports
Primary ciliary dyskinesia (PCD) presents various clinical manifestations, including bronchiectasis, chronic sinusitis, situs inversus, and infertility.
Atsushi Kurokawa, Mitsuko Kondo, Mayoko Tsuji, Yuno Shiota, Azusa Miyoshi, Fumi Miyata, Keiko Kan‐o, Tomohiro Akaba, Ken Arimura, Osamitsu Yagi, Kaname Nakatani, Makoto Ikejiri, Kazuhiko Takeuchi, Etsuko Tagaya   +13 more
doaj   +1 more source

Cytoplasmic-anti-neutrophil cytoplasmic antibodies targeting myeloperoxidase in Wegener′s granulomatosis: A rare phenomenon

Indian Journal of Pathology and Microbiology, 2014
Wegener′s granulomatosis (WG) patients can rarely have antineutrophil cytoplasmic antibodies (ANCAs) directed against myeloperoxidase (MPO), producing a cytoplasmic pattern on indirect immunofluorescence (IIF).
Bhavana M Venkatesh, Sangeeta Joshi, Ranjeeta Adhikary   +2 more
doaj   +1 more source

Microarray detection of human parainfluenzavirus 4 infection associated with respiratory failure in an immunocompetent adult. [PDF]

, 2006
A pan-viral DNA microarray, the Virochip (University of California, San Francisco), was used to detect human parainfluenzavirus 4 (HPIV-4) infection in an immunocompetent adult presenting with a life-threatening acute respiratory illness.
Blackburn, Brian G, Chiu, Charles Y, DeRisi, Joseph L, Eckburg, Paul B, Fischer, Kael, Ganem, Don, Koshy, Anita, Merker, Jason D, Patterson, Bruce K, Rouskin, Silvi, Schnurr, David, Tompkins, Lucy S, Urisman, Anatoly, Yagi, Shigeo   +13 more
core  

Visible diode lasers can be used for flow cytometric immunofluorescence and DNA analysis [PDF]

, 1994
This report describes a feasibility study concerning the use of a visible diode laser for two important fluorescence applications in a flow cytometer. With a 3 mW 635 nm.
de Grooth, B.G., Doornbos, R.M.P., Doornbos, Richard M.P., Greve, Jan, Kraan, Yvonne M., van der Poel, Carel J.   +5 more
core   +2 more sources