Results 81 to 90 of about 730,144 (338)

Direct Immunofluorescence in Oral Lichen Planus.

Journal of clinical and diagnostic research : JCDR, 2015
INTRODUCTION Oral lichen planus (OLP) is a common immune-mediated oral mucosal disease. Diagnosis of OLP depends mainly on both clinical and histopathological features.
W. Buajeeb, Nis Okuma, S. Thanakun, Titikarn Laothumthut   +3 more
semanticscholar   +1 more source

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

Molecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald, Anna M. Reagan, Charles J. Bailey, Mei Gao, Muqiang Gao, Angelica L. Solomon, Michael J. Cavnar, Prakash K. Pandalai, Mautin T. Barry‐Hundeyin, Megan M. Harper, Justin A. Rueckert, Ángela Turrero, Araceli Tobio, Anxo Vidal, Daniel Roca‐Lema, Elia Álvarez‐Coiradas, Pablo Garrido, Laureano Simón, Joseph Kim   +18 more
wiley   +1 more source

Experimental Investigations: Micromeritic Procedures In Assessing Antinuclear Antibody Patterns In Immunofluorescent Assay

Folia Medica, 2014
ЦЕЛЬ: Работа ставит себе целью ввести микрометрическую процедуру (статистический анализ, применя- емый для небольших объектов) в индиректный флюоресцентный анализ в целях получения объективных количественных параметров при анализе локализации ...
Murdjeva Mariana A., Milieva Emilia T., Stefanov Rumen S., Draganov Marian M., Krastev Petko B.   +4 more
doaj   +1 more source

Human Dental Pulp Tissue during Orthodontic Tooth Movement: An Immunofluorescence Study

Journal of Functional Morphology and Kinesiology, 2020
The orthodontic tooth movement is the last step of several biological processes that take place after the application of external forces. During this process, dental pulp tissue is subjected to structural and protein expression modifications in order to ...
Giovanna Vermiglio, Antonio Centofanti, Giovanni Matarese, Angela Militi, Marco Matarese, Alba Arco, Fabiana Nicita, Giuseppina Cutroneo   +7 more
doaj   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Differential Growth Characteristics of Crimean-Congo Hemorrhagic Fever Virus in Kidney Cells of Human and Bovine Origin

Viruses, 2020
Crimean-Congo hemorrhagic fever virus (CCHFV) causes a lethal tick-borne zoonotic disease with severe clinical manifestation in humans but does not produce symptomatic disease in wild or domestic animals. The factors contributing to differential outcomes
Katalin Földes, Touraj Aligholipour Farzani, Koray Ergünay, Aykut Ozkul   +3 more
doaj   +1 more source

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

Molecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach, Nilesh Chatterjee, Kellie Spahr, Gilberto Serrano de Almeida, Anabel Varela‐Carver, Taimur T. Shah, Mathias Winkler, Hashim U. Ahmed, Charlotte L. Bevan   +8 more
wiley   +1 more source

Blowup of Accidental Images as a Passageway to Discovery: Insights into the Interaction between Hydroxyapatite Nanoparticles and Human Mesenchymal Stem Cells

Applied Sciences, 2020
Despite decades of research into the interaction between cells and nanoparticles, there is a lack of consensus regarding how specific physicochemical characteristics of the nanoparticles, including chemical composition, crystallinity, size, morphology ...
Vuk Uskoković
doaj   +1 more source

Direct Immunofluorescence Microscopy

, 2015
Direct immunofluorescence plays an important role in the diagnosis of autoimmune blistering diseases. The purpose of direct immunofluorescence microscopy is to detect in vivo antibodies in patient's skin or mucosa. Direct immunofluorescence of pemphigus shows depositions of immunoglobulins and/or complement on the epithelial cell surface of ...
Diercks, G.F.H., Pas, Hendrikus
openaire   +3 more sources

Immunofluorescence analysis and diagnosis of primary ciliary dyskinesia with radial spoke defects

, 2015
Primary ciliary dyskinesia (PCD) is a genetically heterogeneous recessive disorder caused by several distinct defects in genes responsible for ciliary beating leading to defective mucociliary clearance often associated with randomization of left/right ...
N. Loges, A. Frommer, R. Hjeij, C. Edelbusch, C. Jahnke, J. Raidt, C. Werner, J. Wallmeier, J. G. Onnebrink, H. Olbrich, S. Cindrić, Y. Memari, J. Marthin, K. Nielsen, I. Amirav, Kerem Eitan, D. Shoseyov, Karsten Haeffner, M. Boon, M. Jaspers, H. Omran   +20 more
semanticscholar   +1 more source