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A phase 1, single-center, randomized, dose finding study to evaluate the safety, tolerability, and immunogenicity of a prophylactic COVID-19 pDNA vaccine after single ascending doses in healthy adults. [PDF]

Front Med (Lausanne)
Almansour-Alzamil I.
europepmc   +1 more source

Trimeric hemagglutinin vaccine provides chickens complete protection against lethal H5 subtype avian influenza virus from clade 2.3.4.4b. [PDF]

Emerg Microbes Infect
Chen T, Huang Q, Chen X, Zhu J, Kong D, Liao X, Liao M, Fan H.   +7 more
europepmc   +1 more source

Safety and Immunogenicity of a Fourth Dose of Omicron BA.1-Adapted BNT162b2 COVID-19 Vaccines in Adults 18-55 Years Old. [PDF]

Clin Infect Dis
Winokur P, Diya O, Fitz-Patrick D, Dever M, Gayed J, Lockhart S, Xu X, Zhang Y, Bangad V, Wadsworth LT, Cannon K, Cardona JF, Usdan L, Ginis J, Mensa FJ, Zou J, Xie X, Lu C, Buitrago S, Scully IL, Cooper D, Koury K, Jansen KU, Türeci Ö, Şahin U, Swanson KA, Gruber WC, Kitchin N.   +27 more
europepmc   +1 more source

mRNA vaccines in oncology: personalized cancer immunization and neoantigen targeting. [PDF]

Mol Cell Oncol
Parganiha M, Rathored J, Sai Painkra D.
europepmc   +1 more source

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Immunogenicity of bacteriophages

Trends in Microbiology, 2023
Hundreds of trillions of diverse bacteriophages (phages) peacefully thrive within and on the human body. However, whether and how phages influence their mammalian hosts is poorly understood. In this review, we explore current knowledge and present growing evidence that direct interactions between phages and mammalian cells often induce host ...
Kevin Champagne-Jorgensen, Tiffany Luong, Taylor Darby, Dwayne R. Roach   +3 more
openaire   +2 more sources

The determinants of tumour immunogenicity

Nature Reviews Cancer, 2012
Many standard and targeted therapies, as well as radiotherapy, have been shown to induce an anti-tumour immune response, and immunotherapies rely on modulating the host immune system to induce an anti-tumour immune response.
Thomas Blankenstein, Pierre G Coulie, Eli Gilboa   +2 more
exaly   +2 more sources

Immunogens and Non-Immunogens in the Induction of Tolerance

Nature, 1969
THERE are few reports in the literature of immunological tolerance induced by non-immunogenic substances. In 1965 Maurer et al.1 studied the effects of neonatal injection of synthetic polymers on the subsequent immune response of adult rabbits against related cross-reacting polymers.
C, Collotti, S, Leskowitz
openaire   +2 more sources

Immunogenicity of rifamycins

Molecular Immunology, 1979
Abstract The presence of anti-rifamycin antibodies in sera of rabbits injected with a rifamycin-protein conjugate or with some unconjugated rifamycin derivatives, was assayed by equilibrium dialysis. The conjugate was effective in eliciting the production of rifamycin specific antibodies. This capacity also was exhibited by the derivatives P and S/TA.
G, Mistrello, R, Cricchio, G, Bolzoni, M, Mosca, L, Bassi   +4 more
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Immunogenicity of immunoliposomes

Immunology Letters, 1991
Multilamellar immunoliposomes were prepared from dipalmitoylphosphatidylcholine (DPPC), cholesterol (CH), sphingomyelin (SPH) and biotinylated dipalmitoylphosphatidylethanolamine (PEB) in the molar ratio of 1:1:1:0.1 with surface linked avidin-biotinylated sheep (anti-mouse IgG) IgG (AV-sIgGB) or GK1.5 monoclonal rat (antimouse L3T4 antigen) IgG (AV ...
N C, Phillips, A, Emili
openaire   +2 more sources