Results 301 to 310 of about 350,984 (342)

The Composite Antiadhesion Barrier Facilitated Fibroblast Autophagy Activation for Tendon Repair

Advanced Science, EarlyView.
Synthesis of an innovative three‐layer composite antiadhesion barrier (plasmid DNA@E–H–E′) is schematically illustrated, highlighting its reactive‐oxygen‐species‐responsive, unidirectional interleukin‐37 delivery to enhance fibroblast autophagy, thereby effectively preventing tendon adhesion and promoting scarless tendon repair.
Zhenyu Sun, Jingwen Liu, Liang Chen, Zhen Wang, Fei Wang, Shen Liu   +5 more
wiley   +1 more source

A Lyophilizable Nanoparticle Vaccine Specific for a Novel Linear Neutralizing Epitope in the α2-α3 Helices of Domain 3 of Lethal Factor from <i>Bacillus anthracis</i>. [PDF]

Toxins (Basel)
Oscherwitz J, Cease K, Milich D, Braun T, Yu F, Whitacre D.   +5 more
europepmc   +1 more source

Mitochondrial Transplantation Augments the Reparative Capacity of Macrophages Following Myocardial Injury

Advanced Science, EarlyView.
Mitochondrial transplantation induces macrophage polarization toward an anti‐inflammatory M2 phenotype, enhances their reparative capacities, and facilitates mitochondrial transfer to cardiomyocytes, collectively promoting tissue repair and functional recovery post‐myocardial infarction.
Yuning Zhang, Xiaolei Sun, Yawei Jin, Kanghui Chen, Lu Zhang, Xiong Gao, Mohan Li, Ze Yuan, Jianguo Jia, Aijun Sun, Junbo Ge   +10 more
wiley   +1 more source

Immunogenicity, safety and adverse events of sequential vaccination with a 10-valent pneumococcal conjugate vaccine (PCV10) and PPSV23 compared with PPSV23 alone in systemic lupus erythematosus. [PDF]

Lupus Sci Med
Chatterjee R, Kommaraju SY, Mettingal Ramakrishnan S, Ravikumar KL, Aggarwal A.   +4 more
europepmc   +1 more source

Molecular Design of a Naturally Derived Hemostatic Sealant with Prolonged Antimicrobial Activity for Repairing Elastic Organ Injuries

Advanced Science, EarlyView.
An injectable, photocrosslinkable hydrogel sealant—comprising GelMAG, DMA, and pDDA—demonstrated strong underwater adhesion, elasticity, biocompatibility, and broad‐spectrum antibacterial activity. This material rapidly sealed dynamic internal organ injuries and significantly reduced blood loss in vivo. Its superior performance over commercial products
Saumya Jain, Avijit Baidya, Joshua A. Boys, George Z. Cheng, Taichiro Imahori, Naoki Kaneko, Nasim Annabi   +6 more
wiley   +1 more source

Interactions of Antibody Drug Conjugate Anti‐Tubulin and Topoisomerase I Inhibitor Payloads with Radiotherapy to Potentiate Immunotherapy

Advanced Science, EarlyView.
Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance, Bryan S. Yung, Michael M. Allevato, Marcus M Cheng, Maria F. Camargo, Robert Saddawi‐Konefka, Kanika Dhawan, Ashwyn K. Sharma, Mahsa Mortaja, Sophie Bice, Daniel J. Scanderbeg, Diego Alvarado, Jyoti Mayadev, Ramez N. Eskander, Stephen R. Adams, Pippa F. Cosper, J. Silvio Gutkind, Sunil J. Advani   +17 more
wiley   +1 more source

Considering the immunogenicity of PEG: strategies for overcoming issues with PEGylated nanomedicines. [PDF]

Nanomedicine (Lond)
Shiraishi K.
europepmc   +1 more source

Correction: Immunogenicity of differentially glycosylated Marburg virus glycoproteins expressed in mammalian and insect cells. [PDF]

Virol J
Li J, Wang S, Cui Y, Song L, Song Z, Huang P, Chi X, Fang T, Dong Y, Li R, Fan P, Wang Y, Bi L, Li J, Zhang G, Yu C.   +15 more
europepmc   +1 more source

Generalized Modules for Membrane Antigens (GMMA) Elicit Mild Local Reactogenicity After Intramuscular Injection in Absence of Aluminum Salt Adjuvant. [PDF]

Immun Inflamm Dis
Cecchi R, Maccari S, Alfini R, Di Benedetto R, Gallorini S, Cartocci E, Marchi S, Romagnoli G, Bartolini E, Micoli F, Piccioli D.   +10 more
europepmc   +1 more source