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Immunogens and Non-Immunogens in the Induction of Tolerance [PDF]
Nature, 1969 THERE are few reports in the literature of immunological tolerance induced by non-immunogenic substances. In 1965 Maurer et al.1 studied the effects of neonatal injection of synthetic polymers on the subsequent immune response of adult rabbits against related cross-reacting polymers.
Clelia Collotti, Sidney Leskowitz
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Immunogenic and Non-Immunogenic Hyperthyroidism [PDF]
Nuklearmedizin, 1995 SummaryAnnual occurrences of immunogenic (IH) and non-immunogenic hyperthyroidism (NIH) between Berne (1976, 1982, 1991) and Szczecin (1973, 1980, 1991) were compared. Out of 21,025 patients referred for thyroid examinations, 10.1% (average) were hyperthyroid.
H. Rosier +3 more
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Immunogenicity of bacteriophages
Trends in Microbiology, 2023Hundreds of trillions of diverse bacteriophages (phages) peacefully thrive within and on the human body. However, whether and how phages influence their mammalian hosts is poorly understood. In this review, we explore current knowledge and present growing evidence that direct interactions between phages and mammalian cells often induce host ...
Kevin Champagne-Jorgensen +3 more
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The dendritic cell system and its role in immunogenicity.
Annual Review of Immunology, 1991Dendritic cells are a system of antigen presenting cells that function to initiate several immune responses such as the sensitization of MHC-restricted T cells, the rejection of organ transplants, and the formation of T-dependent antibodies.
R. Steinman
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Molecular Immunology, 1979
Abstract The presence of anti-rifamycin antibodies in sera of rabbits injected with a rifamycin-protein conjugate or with some unconjugated rifamycin derivatives, was assayed by equilibrium dialysis. The conjugate was effective in eliciting the production of rifamycin specific antibodies. This capacity also was exhibited by the derivatives P and S/TA.
Renato Cricchio +4 more
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Abstract The presence of anti-rifamycin antibodies in sera of rabbits injected with a rifamycin-protein conjugate or with some unconjugated rifamycin derivatives, was assayed by equilibrium dialysis. The conjugate was effective in eliciting the production of rifamycin specific antibodies. This capacity also was exhibited by the derivatives P and S/TA.
Renato Cricchio +4 more
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Diabetes, 1972
Highly purified bovine and porcine insulins (single component insulin) did not produce antibodies in rabbits, and the highly purified porcine insulin was less immunogenic in diabetic patients than USP porcine insulin. In rabbits one porcine high molecular weight fraction (peak A) and two bovine high molecular weight fractions (peak A and peak B ...
Mary A. Root +2 more
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Highly purified bovine and porcine insulins (single component insulin) did not produce antibodies in rabbits, and the highly purified porcine insulin was less immunogenic in diabetic patients than USP porcine insulin. In rabbits one porcine high molecular weight fraction (peak A) and two bovine high molecular weight fractions (peak A and peak B ...
Mary A. Root +2 more
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Current Gene Therapy, 2007
The first in vivo adeno-associated viral vector (AAV) gene transfer experiments were performed in murine models of muscle directed gene transfer. These studies were remarkable for stable expression of a variety of immunogenic transgenes. These findings were translated to other target organs with multiple therapeutic gene products.
James M. Wilson, Luk H. Vandenberghe
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The first in vivo adeno-associated viral vector (AAV) gene transfer experiments were performed in murine models of muscle directed gene transfer. These studies were remarkable for stable expression of a variety of immunogenic transgenes. These findings were translated to other target organs with multiple therapeutic gene products.
James M. Wilson, Luk H. Vandenberghe
openaire +3 more sources