Results 61 to 70 of about 66,232 (237)

Immunogenicity profile.

, 2022
Immunogenicity profile.
Andrey L. Bakulev (5727509), Alkes A. Khotko (12054833), Vladislav R. Khairutdinov (10681905), Irina V. Chumachenko (12054839), Valery V. Dubenskiy (12054827), Tat’yana V. Korotaeva (12054818), Antonina V. Artemeva (10681912), Alexey V. Samtsov (10681904), Alexander M. Lukyanov (12054842), Bulat V. Khalilov (12054830), Muza M. Kokhan (10681903), Iskander K. Minullin (12054821), Polina P. Pukhtinskaia (12054845), Olga A. Vylegzhanina (12054824), Olga S. Zykova (12054836)   +14 more
core   +1 more source

Microfluidic Nano‐Assembly of Red‐Blood‐Cell (RBC) Lipids and Components for Engineering Extracellular Vesicles

Advanced Healthcare Materials, EarlyView.
Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj, Xilal Y. Rima, Kim T. Nguyen, Courtney Culkins, Nana Boateng, Jacob Doon‐Ralls, Alejandro Bresolin, Xin Huang, Hong Li, Vahedi Amid, Ajeet Pal Singh, Dharti Shantaram, Anastasiia Amari, Mangesh D. Hade, Nicholas R. Merriam, Zachary D. Schultz, Scott Q. Harper, Nizar Y. Saad, Setty M. Magaña, Willa A. Hsueh, Rachel E. Kopec, Blaise R. Kimmel, Andre F. Palmer, Eduardo Reátegui   +23 more
wiley   +1 more source

Immunogenicity of therapeutic peptide products: bridging the gaps regarding the role of product-related risk factors

Frontiers in Immunology
The global market for therapeutic peptides is projected to continue to grow at a fast pace in the coming years in response to high demand for these products. The increasing complexity of chemical and recombinant peptide manufacturing processes may impact
Montserrat Puig, Sophie Shubow
doaj   +1 more source

Satisfactory safety and immunogenicity of MSP3 malaria vaccine candidate in Tanzanian children aged 12-24 months. [PDF]

, 2009
BACKGROUND: Development and deployment of an effective malaria vaccine would complement existing malaria control measures. A blood stage malaria vaccine candidate, Merozoite Surface Protein-3 (MSP3), produced as a long synthetic peptide, has been shown ...
Gesase Samwel, Druilhe, Pierre, Chilengi Roma, Roma Chilengi, Method D Segeja, Seth, Misago, Msham Salum, Francis Filbert, Lemnge, Martha, Samwel Sembuche, Salum Msham, Noor Ramadhani, Cousens Simon, Sembuche, Samwel, Minja Daniel, Martha Lemnge, Simon Cousens, Samuel Bosomprah, Chilengi, Roma, Samwel Gesase, Lusingu, John PA, Gesase, Samwel, John PA Lusingu, Rutta, Acleus, Bosomprah Samuel, Cousens, Simon, Ramadhani Noor, Acleus Rutta, Pierre Druilhe, Seth Misago, Segeja Method D, Minja, Daniel, Msham, Salum, Druilhe Pierre, Daniel Minja, Francis, Filbert, Noor, Ramadhani, Lemnge Martha, Bosomprah, Samuel, Lusingu John PA, Rutta Acleus, Misago Seth, Segeja, Method D, Sembuche Samwel, Filbert Francis   +44 more
core   +1 more source

A Systematic Study of GelMA‐Carbopol Bioinks for High‐Fidelity Extrusion 3D Bioprinting at Physiological Temperatures

Advanced Healthcare Materials, EarlyView.
Gonzalez Martinez and collaborators develop a strategy to formulate high performance GelMA‐based bioinks with low solids contents. The resulting bioinks enable 3D bioprinting at 37 °C of high‐fidelity structures with tunable mechanical properties that support high cell viability and function.
David A. González‐Martínez, Aidee V. Arizpe Tafoya, Eduardo González‐Martínez, Mabel Barreiro Carpio, Laura Daniela Serrano Andrade, Christopher T. N. Chow, Mohammadhossein Dabaghi, Jeremy A. Hirota, Jose M. Moran‐Mirabal   +8 more
wiley   +1 more source

Dynamic Loading Regulates Meniscus‐Like Matrix Production in Human Mesenchymal Stromal Cell‐Seeded PET Scaffolds

Advanced Healthcare Materials, EarlyView.
Dynamic compression enhances mesenchymal stromal cell proliferation in nonwoven PET scaffolds under chondrogenic differentiation conditions and triggers mechanosensitive transcriptional programs associated with extracellular matrix remodeling. These findings highlight the potential of mechanically stimulated PET scaffolds as a promising platform for ...
Graciosa Quelhas Teixeira, Luisa de Roy, Anna‐Lotta Feldmeier, Mubashir Ahmad, Sofia Pilão, Maria Ahrens, Anita Ignatius, Carsten Linti, Andreas Martin Seitz   +8 more
wiley   +1 more source

Mitochondria‐Targeted Nanotherapies in Aging Neurodegenerative Disorders: Emerging Prospects and Clinical Potential

Advanced Healthcare Materials, EarlyView.
Mitochondria‐targeted nanotherapies emerge as a promising strategy for combating aging‐associated neurodegenerative disorders (NDs) by restoring mitochondrial function, reducing oxidative stress, and improving neuronal survival. Recent advances in nanotechnology, therapeutic delivery, and translational research are highlighted, providing insights into ...
Dnyandev G. Gadhave, Ashish B. Jadhav, Nitin B. Waghamode, Shubham Khot, Rajiya Khan, Ravi Hole, Shankar M. Dhobale, Manoj Aswar, Keshav Raj Paudel   +8 more
wiley   +1 more source

Tumor‐Targeted Hyaluronic Acid/Tannic Acid‐Engineered Oxygen Nanogenerators With IR780 Payloads Enable Dual‐Mode Glutathione Depletion and Effective Singlet Oxygen Generation for Melanoma Treatment

Advanced Healthcare Materials, EarlyView.
A hyaluronic acid/tannic acid‐engineered Prussian blue oxygen nanogenerator loaded with IR780 is developed to enhance melanoma phototherapy. By integrating tumor targeting, oxygen self‐supply, and dual‐mode glutathione depletion, the nanoplatform effectively overcomes hypoxia and antioxidant defenses, potentiating synergistic photothermal/photodynamic ...
Chai‐How Hsu, I‐Ju Liu, Hsiang‐Yun Chih, Tsai‐Ching Hsu, Ju‐An Liang, Chia‐Wei Kuo, Bor‐Show Tzang, Wen‐Hsuan Chiang   +7 more
wiley   +1 more source

How is Nanoarchitectonics Shaping Extracellular Vesicle Research?

Advanced Healthcare Materials, EarlyView.
The convergence of nanoarchitectonics and extracellular vesicle biology is reshaping next‐generation nanomedicine by enabling rationally designed nanostructures for enhanced EVs detection, engineering, and therapy. ABSTRACT Extracellular vesicles (EVs) have gained recognition as crucial mediators of cell‐to‐cell communication, holding immense potential
Madushani Dahanayake, Md Shahriar A. Hossain, Chia‐Hung Liu, Carlos Salomon, Yusuke Yamauchi, Mostafa Kamal Masud   +5 more
wiley   +1 more source

Development of the quadrivalent live attenuated influenza vaccine including two influenza B lineages – Victoria and Yamagata

Вопросы вирусологии, 2016
This work is devoted to the research of the live attenuated influenza vaccine (LAIV) comprising two reassortant B/USSR/60/69-based vaccine influenza viruses Victoria and Yamagata.
Yu. A. Desheva, T. A. Smolonogina, E. M. Doroshenko, L. G. Rudenko   +3 more
doaj   +1 more source