Results 71 to 80 of about 238,930 (305)

Influence of glycosylation on the immunogenicity and antigenicity of viral immunogens

Biotechnology Advances
A key aspect of successful viral vaccine design is the elicitation of neutralizing antibodies targeting viral attachment and fusion glycoproteins that embellish viral particles. This observation has catalyzed the development of numerous viral glycoprotein mimetics as vaccines.
Maddy L, Newby, Joel D, Allen, Max, Crispin   +2 more
openaire   +2 more sources

Immunogenicity overview of therapeutic biologics

, 2017
<p>Hello, everyone. Welcome to watch the video named immunogenicity overview of therapeutic biologics which created by creative biolabs. In this video, we will introduce the definition of immunogenicity, background of immunogenicity and importance ...
Creative Biolabs
core   +1 more source

The chemotherapeutic agent DMXAA as a unique IRF3-dependent type-2 vaccine adjuvant [PDF]

, 2013
5,6-Dimethylxanthenone-4-acetic acid (DMXAA), a potent type I interferon (IFN) inducer, was evaluated as a chemotherapeutic agent in mouse cancer models and proved to be well tolerated in human cancer clinical trials.
Cevayir Coban, Kenji Mizuguchi, Junichi Ito, Etsushi Kuroda, Coban, C, Ishii, KJ, Choon Kit Tang, Shizuo Akira, Jounai, N, Benoit H Dessailly, Ito, J, Keiichi Ohata, Tang, CK, Akira, S, Mizuguchi, K, Ken J Ishii, Kouji Kobiyama, Ohata, K, Nao Jounai, Kuroda, E, Kobiyama, K, Dessailly, BH, Aoshi, T, Taiki Aoshi   +23 more
core   +1 more source

Dexime: A Selectively Enzyme‐Degradable Hydrogel for Protein Therapeutic Release

Advanced Materials, EarlyView.
A dextrin‐oxime hydrogel (dexime) is produced using ketone or aldehyde modified dextrin and tetra‐oxyamine modified poly(ethylene glycol). The rheological and mechanical properties of dexime are tunable. Dexime is injectable, cytocompatible, hydrolytically stable, and selectively degradable by α‐amylase.
Quinton E. A. Sirianni, Nitzan Letko Khait, Adam Forman, Edward A. Armstrong, Karim Fouad, Molly S. Shoichet   +5 more
wiley   +1 more source

Baseline characteristics of immunogenicity cohort.

, 2021
Baseline characteristics of immunogenicity cohort.
Ousmane Guindo (35279), Monica Malone McNeal (11067898), Souna Garba (11067904), Céline Langendorf (624676), Eric Adehossi (308400), Iza Ciglenecki (446458), Brian Plikaytis (11067901), Rebecca F. Grais (8151654), Sheila Isanaka (323429)   +8 more
core   +1 more source

Double‐Transition‐Metal MXenes: Multimetallic 2D Platforms for Next‐Generation Biomedicine

Advanced Materials, EarlyView.
The present work explores recent progress in double‐transition‐metal MXenes and focuses on their potential as multifunctional biomedical nanoplatforms whose tunable optical, electronic, mechanical, and surface properties enable imaging, theranostics, antimicrobial activity, biosensing, tissue engineering, and drug delivery.
Parsa Namakiaraghi, Mohammad Mozafari, Masoud Soroush   +2 more
wiley   +1 more source

Vaccine delivery systems based on amphiphilic bioresorbable polymers and their role in vaccine immunogenicity

, 2011
[[abstract]]Efficacy and safety are two of the key challenges in vaccine and immunotherapy technology. To these ends, one needs to strengthen manipulating and to deepen understanding the immune system.
Huang, MH;Leng, CH;Liu, SJ;Chen, HW;Sia, C;Chong, P
core  

Development of methods for the in-vitro assessment of the adipogenesis and immunogenicity of human multipotent mesenchymal stromal cells [PDF]

, 2011
Adult mesenchymal stromal cells (MSCs) have enormous potential in tissue engineering and regenerative medicine applications. MSC have also been reported to be immune-privileged.
Aldridge, Andrew Robert
core  

Super‐Resolution Ultrasound Based Cell Tracking With Polymeric Nanobubbles

Advanced Materials, EarlyView.
This study presents a super‐resolution ultrasound platform for tracking cells in vivo. Biocompatible polymeric nanobubbles are used as highly echogenic intracellular labels. Following the injection of cells and microbubbles, ultrasound localization microscopy (ULM) can dynamically match the microvascular architecture and individual cell trajectories ...
Junlin Chen, Xiaoyu Wang, Jilin Fan, Bi Wang, Hanghang Fang, Yurui Wang, Hao Cui, Mohammad Roufarshbaf, Ekaterina Savina, Alexandra Valeske, Quim Peña, Yang Shi, Andreas Herrmann, Twan Lammers, Mathias Hornef, Roman Barmin, Thomas Lisson, Georg Schmitz, Anne Rix, Fabian Kiessling   +19 more
wiley   +1 more source

Immunogenicity of red blood cell blood group antigens in the population of Xi'an

Zhongguo shuxue zazhi
[Objective] To evaluate the immunogenicity of red blood cell blood group antigens in the population of Xi'an. [Methods] Data on blood group antigens of voluntary blood donors from the Shaanxi Province Blood Center and unexpected antibody detection ...
ZHANG Liangzi, ZUO Qinqin, XU Hua, ZHANG Yong, WU Dazhou, TIAN Xue, CHU Xiaoyue   +6 more
doaj   +1 more source