Cell adhesion molecule 1 is upregulated in connective tissue mast cells and potentially contributes in IgE-mediated degranulation. [PDF]
Hagiyama M +4 more
europepmc +1 more source
Adding mountain mint (Ziziphora clinopodioides Lam.) to diet of laying quails resulted in the production of elongated eggs, improved blood lipid profiles and immune responses. ABSTRACT Background Mountain mint (MM), a traditional herbal remedy, has garnered attention for its potential benefits on poultry health and productivity.
Ahmad Hassanabadi +2 more
wiley +1 more source
Effects of <i>Otostegia persica</i> and <i>Boerhavia elegans</i> leaf powders on performance, egg quality, blood metabolites, and antioxidant status in laying Japanese quails. [PDF]
Saleh H, Ganji PA, Mirakzehi MT.
europepmc +1 more source
A Bruchs membrane (BrM) mimic based on aged decellularized BrM was developed and differentially expressed proteins in aged dECM‐BrM that may provide specific biochemical cues fundamental to model AMD in vitro were identified. RPE culture on aged dECM‐BrM developed certain AMD‐like features including reduced TEER and expression of drusen components ...
Blanca Molins +8 more
wiley +1 more source
Acute effects of continuous and interval cycling on salivary SIgA and anti-microbial peptide secretions: a randomized crossover trial. [PDF]
Ito R +8 more
europepmc +1 more source
Aging‐Driven Immunosuppression: The Role of Tregs in the Ovarian Tumor Microenvironment
In the aged ovarian TME, cancer cells exhibit increased succinate production. Elevated extracellular succinate activates the SUCNR1 receptor on Tregs, promoting their recruitment and contributing to an immunosuppressive environment. This leads to diminished anti‐tumor T cell responses and reduced survival.
Mary P. Udumula +10 more
wiley +1 more source
Research progress on the role of MZB1 in immune regulation. [PDF]
Liu W, Jiang K, Jin M, Chen X.
europepmc +1 more source
Organ‐specific aging clocks integrating genomics, epigenomics, transcriptomics, proteomics, and metabolomics offer a more accurate assessment of biological aging than single‐omics approaches. This review proposes a multi‐omics framework emphasizing tissue data, longitudinal study designs, and clinically meaningful training outcomes to advance the ...
Maria Vasileiou +3 more
wiley +1 more source
Influence of Ordinary Cigarettes and Their Substitute IQOS<sup>®</sup> on Secretory Immunoglobulin A in Unstimulated Saliva. [PDF]
Pavlov N +6 more
europepmc +1 more source
T Cell Immunosenescence in Inflammatory Skin Diseases: Pathogenesis and Therapeutic Targets
Immunosenescent T cells promote inflammatory skin diseases such as psoriasis, atopic dermatitis, rosacea, and seborrheic dermatitis via hyperactive signaling networks and SASP secretion. Consequently, intercepting downstream SASP, inhibiting internal pathways, or utilizing senolytics represents promising therapeutic interventions.
Conghui Liu +3 more
wiley +1 more source

