Results 211 to 220 of about 95,011 (294)

The Effects of Periodontal Treatment on Psoriasis: A Systematic Review of Limited Clinical and Preclinical Evidence. [PDF]

J Clin Med
Condor DC, Copaciu-Condor AM, Kui A, Negucioiu M, Buduru S, Lucaciu OP.   +5 more
europepmc   +1 more source

Aged Gut Microbiota Induces Mucosal Transcriptional Dysregulation, Impairing Immune Surveillance

Aging Cell, Volume 25, Issue 5, May 2026.
Aging impaired intestinal mucosal immune homeostasis by altering the epithelial barrier, lamina propria immune cells, follicle‐associated epithelium, and gut microbiota. These changes, particularly the accumulation of pro‐inflammatory bacteria in the gut microbiota, are closely associated with dysregulation of follicle‐associated epithelium gene ...
Fang Wu, Ming Zhang, Jianmin Wu, Zihan Wang, Yumeng Ma, Lin Dong, Le Cheng, Tengteng Ji, Chenyan Zheng, Fazheng Ren, Bing Fang   +10 more
wiley   +1 more source

Lacrimal gland duct obstruction and dacryops: Unravelling its pathogenesis with proteomics and cellular profiling. [PDF]

Ocul Surf
Singh S.
europepmc   +1 more source

Beyond the Barrier: Epithelial Cells as Immune Sentinels in the Female Genital Tract

American Journal of Reproductive Immunology, Volume 95, Issue 5, May 2026.
ABSTRACT Epithelial cells (ECs) of the female genital tract (FGT) serve as an essential barrier and the first line of defense against sexually transmitted pathogens. Beyond providing a physical barrier, these cells actively contribute to immune responses through pathogen recognition, cytokine release, and modulation of adaptive immune responses ...
Lauren Jirik, Shreya Joshi, Aisha Nazli, Charu Kaushic   +3 more
wiley   +1 more source

Infantile Systemic Hyalinosis: A Familiar Symptom Unveiling an Unusual Disease. [PDF]

Cureus
Nayek S, Sandhu A, Kumar A, Malik S.
europepmc   +1 more source

Folding, misfolding, and regulation of intracellular traffic of G protein‐coupled receptors involved in the hypothalamic–pituitary–gonadal axis

Andrology, Volume 14, Issue 4, Page 978-991, May 2026.
Abstract Background G protein‐coupled receptors are a large and functionally diverse family of membrane receptors involved in a number of biological processes. Like other proteins, G protein‐coupled receptors need to be properly folded in order to traffic to the plasma membrane and interact with agonist.
Alfredo Ulloa‐Aguirre, Ross C. Anderson, Teresa Zariñán, Rubén Gutiérrez‐Sagal, Eduardo Jardón‐Valadez, Claire L. Newton   +5 more
wiley   +1 more source

Engineered IgA-Fc fusion protein with bioactive nanobody neutralizes SARS-CoV-2 variants with mucosal delivery potential. [PDF]

J Biol Chem
Golonka RM, Intravaia LE, Shaqra AM, Li Q, Chen Y, Humphries F, Kurt-Yilmaz N, Fitzgerald KA, Schiffer CA, Wang Y, Cavacini LA.   +10 more
europepmc   +1 more source

Teplizumab in Stage 2 Type 1 Diabetes: Clinical Practice Experience on Feasibility in 3 Adult Patients

Diabetes, Obesity and Metabolism, Volume 28, Issue 5, Page 4326-4334, May 2026.
ABSTRACT Aim To describe the first Italian experience with teplizumab administered under a compassionate use programme for adults with Stage 2 type 1 diabetes (T1D), and to evaluate its feasibility, safety and early metabolic outcomes in a real‐life clinical setting outside formal clinical trials.
V. Guarnotta, F. Pantò, E. Vigneri, G. Piombo, M. I. Mineo, L. Tomasello, G. Arnaldi   +6 more
wiley   +1 more source

Building better antibody responses: The interplay of infection, vaccination, and immune imprinting. [PDF]

PNAS Nexus
Carissa Aurelia L, Selva KJ, Chung AW.
europepmc   +1 more source

Lifelong Exercise as a Modulator of CD4+ T Cell Immunometabolism

European Journal of Clinical Investigation, Volume 56, Issue 5, May 2026.
Hypothetical framework illustrating how physical exercise initiated early in life acts as a critical immunomodulatory factor by promoting optimal immune function from childhood and establishing a better “immunometabolic functional peak”. This early advantage may confer sustained benefits to CD4+ T cell metabolism and immune competence across aging ...
Bruna Spolador de Alencar Silva, Amanda Veiga Sardeli, Ricardo R. Agostinete, Helena Batatinha, Alessandra Peres, José César Rosa‐Neto, José Teixeira, Manuel J. Coelho‐e‐Silva, Paulo J. Oliveira, Fábio Santos Lira   +9 more
wiley   +1 more source