Results 11 to 20 of about 812,706 (311)

Role of the intestinal MALT in pathogenesis of the IgA-nephropathy

Терапевтический архив, 2021
Modern view on pathogenesis of immunoglobulin (Ig)A-nephropathy and possible relation to intestinal MALT-system activity is presented in the article. Aberrant glycosylation of IgA and increased association of IgA-nephropathy with intestinal diseases or ...
Sergei V. Guliaev, Leonid A. Strizhakov, Natalia V. Chebotareva, Sergei V. Moiseev   +3 more
doaj   +1 more source

Sialendoscopic management of autoimmune sialadenitis: a review of literature [PDF]

, 2017
Autoimmune diseases of major salivary glands include Sjögren's syndrome and a complex of disorders classified as immunoglobulin G4-related diseases.
DE VINCENTIIS, Marco, DE VIRGILIO, Armando, Fusconi, Massimo, Gallo, Andrea, Greco, Antonio, Martellucci, Salvatore, Pagliuca, Giulio   +6 more
core   +2 more sources

Immunoglobulin-A [PDF]

mAbs, 2011
Although immunoglobulin (Ig) A is commonly recognized as the most prevalent antibody subclass at mucosal sites with an important role in mucosal defense, its potential as a therapeutic monoclonal antibody is less well known. However, IgA has multifaceted anti-, non-, and pro-inflammatory functions that can be exploited for different immunotherapeutical
Bakema, J.E., van Egmond, M.
openaire   +5 more sources

Dynamic immunoglobulin responses to gut bacteria during inflammatory bowel disease

Gut Microbes, 2020
Aberrant immune responses against gut microbiota are thought to be key drivers of inflammatory bowel disease (IBD) pathogenesis. However, the extent and targets of immunoglobulin (Ig) A versus IgG responses to gut bacteria in IBD and its association with
Sunaina Rengarajan, Emily E. Vivio, Miles Parkes, Daniel A. Peterson, Elisha D.O. Roberson, Rodney D. Newberry, Matthew A. Ciorba, Chyi-Song Hsieh   +7 more
doaj   +1 more source

Circadian Rhythm of Salivary Immunoglobulin A and Associations with Cortisol as A Stress Biomarker in Captive Asian Elephants (Elephas maximus)

Animals, 2020
Salivary immunoglobulin A (sIgA) has been proposed as a potential indicator of welfare for various species, including Asian elephants, and may be related to adrenal cortisol responses.
Tithipong Plangsangmas, Janine L. Brown, Chatchote Thitaram, Ayona Silva-Fletcher, Katie L. Edwards, Veerasak Punyapornwithaya, Patcharapa Towiboon, Chaleamchat Somgird   +7 more
doaj   +1 more source

Optimization of immunoglobulin substitution therapy by a stochastic immune response model [PDF]

, 2009
Background: The immune system is a complex adaptive system of cells and molecules that are interwoven in a highly organized communication network. Primary immune deficiencies are disorders in which essential parts of the immune system are absent or do ...
Marc Thilo Figge, Derya Unutmaz, E Mix, CA Janeway, ICM MacLennan, T Manser, M Meyer-Hermann, MT Figge, L Marodi, OC Bruton, RH Buckley, HB Gaspar, D Vetrie, S Tsukadab, JS Orange, M Stangel, M Berger, MM Eibl, J Kirmse, A Gardulf, ML Moore, H Milgrom, J Bayry, AG MacGregor, H Fujikawa, JF Van Impe, M Peleg, AS Perelson, WH Press, H Risken, MD Kazatchkine, T Tha-In, J Bayry, V Hurez, S Kaveri, P Aukrust, J Andersson, T Jungi, M Stangel, T Takai, N Prasad, MT Figge   +41 more
core   +1 more source

Stage progression and neurological symptoms in Trypanosoma brucei rhodesiense sleeping sickness: role of the CNS inflammatory response [PDF]

, 2012
Background: Human African trypanosomiasis progresses from an early (hemolymphatic) stage, through CNS invasion to the late (meningoencephalitic) stage.
A Hainard, B Beutler, B Courtioux, B Namangala, CA Hunter, CA Hunter, CF Calvo, EN Benveniste, F Checchi, F Esamai, G Binz, H Reiber, H Reiber, H Reiber, Hansotto Reiber, HY Hassan, J Kabore, J Rodgers, Jeremy M. Sternberg, JM Sternberg, JM Sternberg, JM Sternberg, Joseph Mathu Ndung'u, KW Moore, L Maclean, L MacLean, L MacLean, L MacLean, LJ Morrison, LM MacLean, Lorna MacLean, M Sjogren, MC Okomo-Assoumou, P Cattand, PD Eckersall, Peter G. E. Kennedy, PG Kennedy, PGE Kennedy, PGE Kennedy, TN Baral, V Jamonneau, V Lejon, V Lejon, V Lejon, W Masocha   +44 more
core   +4 more sources

Genomic Organization, Splice Variants and Expression of CGMl, a CD66-related Member of the Carcinoembryonic Antigen Gene Family [PDF]

, 1993
The tumor marker carcinoembryonic antigen (CEA) belongs to a family of proteins which are composed of one immunogiobulin variable domain and a varying number of immunoglobulin constant-like domains.
Afar D. E. H., Audette M., Baniyash M., Berling B., Culic O., Elsen P., Felgner P. L., Fiddes J. C., Knapp W., Kolbinger F., Kuroki M., Kuroki M., Kuroki M., Lin S.-H., Lucas K., Margolis R. N., McCuaig K., Nap M., Neumaier M., Ng S. Y., Oikawa S., Oikawa S., Paxton R., Pelegrin A., Raskind W. H., Rojas M., Sambrook J. E., Schwarz K., Shively J. E., Skubitz K. M., Southern P. J., Thompson J. A., Thompson J. A., Turbide C., Tynan K., Watt S. M., Woodgett J. R., Zhou H.   +37 more
core   +2 more sources

Stressful life events are associated with low secretion rates of immunoglobulin A in saliva in the middle aged and elderly [PDF]

, 2006
Whether chronic stress experience is related to down-regulation of secretory immunoglobulin A (S-IgA) was tested in two substantial cohorts, one middle-aged (N = 640) and one elderly (N = 582), comprising similar numbers of men (N = 556) and women (N ...
Phillips, A.C., Carroll, D., Evans, P., Bosch, J.A., Clow, A., Hucklebridge, F., Der, G., Phillips, A.C., Carroll, D., Evans, P., Bosch, J.A., Clow, A., Hucklebridge, F., Der, G.   +13 more
core   +1 more source

Severity of foot process effacement is associated with proteinuria in patients with IgA nephropathy

Kidney Research and Clinical Practice, 2020
Background : : Proteinuria is a significant risk factor for progression of IgA nephropathy (IgAN) and has a positive correlation with severity of foot process effacement (FPE).
Ji-Hye Lee, Si-Hyong Jang, Nam-Jun Cho, Nam Hun Heo, Hyo-Wook Gil, Eun Young Lee, Jong-Seok Moon, Samel Park   +7 more
doaj   +1 more source