Concurrent Anti-glomerular Basement Membrane Nephritis and IgA Nephropathy [PDF]
Anti–glomerular basement membrane (GBM) nephritis is characterized by circulating anti-GBM antibodies and crescentic glomerulonephritis (GN) with deposition of IgG along the GBM.
Kwang-Sun Suh +4 more
doaj +1 more source
Anaphylactoid Reactions Following Red Blood Cell Transfusion in a Patient with Previously Undiagnosed Immunoglobulin A Deficiency: Case Report [PDF]
A 73-year-old, 104 kg female patient was hospitalised for debulking and low anterior colon resection operations. Anaphylactoid symptoms devel-oped when administering erythrocyte suspension and fresh frozen plasma.
Tümay Uludağ Yanaral +7 more
core +1 more source
Role of the intestinal MALT in pathogenesis of the IgA-nephropathy
Modern view on pathogenesis of immunoglobulin (Ig)A-nephropathy and possible relation to intestinal MALT-system activity is presented in the article. Aberrant glycosylation of IgA and increased association of IgA-nephropathy with intestinal diseases or ...
Sergei V. Guliaev +3 more
doaj +1 more source
Gene conversion in human rearranged immunoglobulin genes [PDF]
Over the past 20 years, many DNA sequences have been published suggesting that all or part of the V<sub>H</sub> segment of a rearranged immunoglobulin gene may be replaced in vivo. Two different mechanisms appear to be operating. One of these
Darlow, J.M. +3 more
core +1 more source
Dynamic immunoglobulin responses to gut bacteria during inflammatory bowel disease
Aberrant immune responses against gut microbiota are thought to be key drivers of inflammatory bowel disease (IBD) pathogenesis. However, the extent and targets of immunoglobulin (Ig) A versus IgG responses to gut bacteria in IBD and its association with
Sunaina Rengarajan +7 more
doaj +1 more source
Salivary immunoglobulin A (sIgA) has been proposed as a potential indicator of welfare for various species, including Asian elephants, and may be related to adrenal cortisol responses.
Tithipong Plangsangmas +7 more
doaj +1 more source
Localization, analysis and evolution of transposed human immunoglobulin VK genes [PDF]
The localization of Vκ gene regions to chromosome 2, on which the κ locus is located, and to other chromosomes is described. The Vκ genes that have been transposed to other chromosomes are called orphons.
Klopstock, Thomas +6 more
core +1 more source
Primary vs. Secondary Antibody Deficiency: Clinical Features and Infection Outcomes of Immunoglobulin Replacement [PDF]
Secondary antibody deficiency can occur as a result of haematological malignancies or certain medications, but not much is known about the clinical and immunological features of this group of patients as a whole. Here we describe a cohort of 167 patients
Matthew Buckland (589995) +27 more
core +1 more source
The immunoglobulin κ gene families of human and mouse: a cottage industry approach [PDF]
Some aspects of the work of our group on the human and mouse immunoglobulin κ genes are reviewed. The human κ locus contains a large duplication: a 600 kb C κ-proximal copy with 40 V κ genes is found in the close vicinity of a 440 kb C κ-distal copy with
Zachau, Hans G.
core +1 more source
Severity of foot process effacement is associated with proteinuria in patients with IgA nephropathy
Background : : Proteinuria is a significant risk factor for progression of IgA nephropathy (IgAN) and has a positive correlation with severity of foot process effacement (FPE).
Ji-Hye Lee +7 more
doaj +1 more source

