Results 41 to 50 of about 114,495,754 (310)

Morphine-induced intestinal microbial dysbiosis drives TLR-dependent IgA targeting of gram-positive bacteria and upregulation of CD11b and TLR2 on a sub-population of IgA+ B cells

open access: yesGut Microbes
IgA binding dictates the composition of the intestinal microbiome and reflects dysbiotic states during chronic disease. Both pathogenic and commensal bacteria differentially bind to IgA with varying outcomes.
Nicolas Vitari   +10 more
doaj   +1 more source

6th International Immunoglobulin Symposium: poster presentations [PDF]

open access: yes, 2009
The posters presented at the 6th International Immunoglobulin Symposium covered a wide range of fields and included both basic science and clinical research.
van Schaik, I N   +67 more
core   +2 more sources

Fish Immunoglobulins [PDF]

open access: yesBiology, 2016
The B cell receptor and secreted antibody are at the nexus of humoral adaptive immunity. In this review, we summarize what is known of the immunoglobulin genes of jawed cartilaginous and bony fishes. We focus on what has been learned from genomic or cDNA sequence data, but where appropriate draw upon protein, immunization, affinity and structural ...
Sara Mashoof, Michael F. Criscitiello
openaire   +3 more sources

Severity of foot process effacement is associated with proteinuria in patients with IgA nephropathy

open access: yesKidney Research and Clinical Practice, 2020
Background : : Proteinuria is a significant risk factor for progression of IgA nephropathy (IgAN) and has a positive correlation with severity of foot process effacement (FPE).
Ji-Hye Lee   +7 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Effectiveness of Revised Trauma-Focused Cognitive Behavioral Therapy Protocol on Psychological Distress and Immunoglobulin A Concentration in Women Victims of Domestic Violence

open access: yesArmaghane Danesh Bimonthly Journal, 2022
Background & aim: Domestic violence has been one of the most common social harms throughout human history, and due to its widespread effect, the pathology and treatment of this phenomenon has always been the focus of therapists. Therefore, the purpose of
SZ Kazemi Khoban   +3 more
doaj  

Intravenous immunoglobulin treatment in children with PANS/PANDAS conditions [PDF]

open access: yes, 2021
Key messages: PANS (Pediatric Acute onset Neuropsychiatric Syndrome)/PANDAS (Pediatric Autoimmune Neuropsychiatric Disorder Associated with Streptococcal infections) is described as an abrupt, dramatic onset of obsessive-compulsive disorder (OCD) or ...
Grøvan, Anette Olsson   +1 more
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Differences in the immunoglobulin gene repertoires of IgG versus IgA multiple myeloma allude to distinct immunopathogenetic trajectories

open access: yesFrontiers in Oncology, 2023
The analysis of the immunogenetic background of multiple myeloma (MM) has proven key to understanding disease ontogeny. However, limited information is available regarding the immunoglobulin (IG) gene repertoire in MM cases carrying different heavy chain
Glykeria Gkoliou   +20 more
doaj   +1 more source

A Novel Immunoglobulin-Immunoglobulin Interaction in Autoimmunity

open access: yesPLoS ONE, 2008
Well over six decades since its first description, the Rheumatoid Factor (RF)-autoantibodies recognizing Fc (constant) portion of IgG through their own Fab (antigen binding variable segments)-is believed to have come of age. Autoimmune pancreatitis is a unique form of pancreatitis, biologically characterized by an elevated serum IgG4 concentration ...
Shigeyuki Kawa   +10 more
openaire   +4 more sources

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