Results 21 to 30 of about 527,999 (266)

Fish Immunoglobulins [PDF]

Biology, 2016
The B cell receptor and secreted antibody are at the nexus of humoral adaptive immunity. In this review, we summarize what is known of the immunoglobulin genes of jawed cartilaginous and bony fishes. We focus on what has been learned from genomic or cDNA sequence data, but where appropriate draw upon protein, immunization, affinity and structural ...
Sara Mashoof, Michael F. Criscitiello
openaire   +3 more sources

Morphine-induced intestinal microbial dysbiosis drives TLR-dependent IgA targeting of gram-positive bacteria and upregulation of CD11b and TLR2 on a sub-population of IgA+ B cells

Gut Microbes
IgA binding dictates the composition of the intestinal microbiome and reflects dysbiotic states during chronic disease. Both pathogenic and commensal bacteria differentially bind to IgA with varying outcomes.
Nicolas Vitari, Salma Singh, Junyi Tao, Bridget Truitt, Udhghatri Kolli, Richa Jalodia, Kathryn M LaPorte, Yaa Abu, Danielle Antoine, Umakant Sharma, Sabita Roy   +10 more
doaj   +1 more source

Severity of foot process effacement is associated with proteinuria in patients with IgA nephropathy

Kidney Research and Clinical Practice, 2020
Background : : Proteinuria is a significant risk factor for progression of IgA nephropathy (IgAN) and has a positive correlation with severity of foot process effacement (FPE).
Ji-Hye Lee, Si-Hyong Jang, Nam-Jun Cho, Nam Hun Heo, Hyo-Wook Gil, Eun Young Lee, Jong-Seok Moon, Samel Park   +7 more
doaj   +1 more source

A Novel Immunoglobulin-Immunoglobulin Interaction in Autoimmunity

PLoS ONE, 2008
Well over six decades since its first description, the Rheumatoid Factor (RF)-autoantibodies recognizing Fc (constant) portion of IgG through their own Fab (antigen binding variable segments)-is believed to have come of age. Autoimmune pancreatitis is a unique form of pancreatitis, biologically characterized by an elevated serum IgG4 concentration ...
Shigeyuki Kawa, Kei Kitahara, Hideaki Hamano, Yayoi Ozaki, Norikazu Arakura, Kaname Yoshizawa, Takeji Umemura, Masao Ota, Sadaaki Mizoguchi, Yasunori Shimozuru, Seiamak Bahram   +10 more
openaire   +4 more sources

Natural Killer Cells in Paediatric Soft Tissue Sarcomas: A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Paediatric soft tissue sarcomas (pSTS) are a rare and heterogeneous group of malignant tumours arising in tissues of mesenchymal origin. The role of natural killer (NK) cells in pSTS remains poorly understood, with evidence fragmented across small preclinical studies and early‐phase clinical trials.
Raya Dean, Lara V. Graham, Christina Putnam, Rosa Gomes Alves Martins, Daniel T. Harding, Tim J. Underwood, Zoë S. Walters, Matthew D. Blunt   +7 more
wiley   +1 more source

Effectiveness of Revised Trauma-Focused Cognitive Behavioral Therapy Protocol on Psychological Distress and Immunoglobulin A Concentration in Women Victims of Domestic Violence

Armaghane Danesh Bimonthly Journal, 2022
Background & aim: Domestic violence has been one of the most common social harms throughout human history, and due to its widespread effect, the pathology and treatment of this phenomenon has always been the focus of therapists. Therefore, the purpose of
SZ Kazemi Khoban, H Poursharifi, A Kakavand, M Xian Bagheri   +3 more
doaj  

Differences in the immunoglobulin gene repertoires of IgG versus IgA multiple myeloma allude to distinct immunopathogenetic trajectories

Frontiers in Oncology, 2023
The analysis of the immunogenetic background of multiple myeloma (MM) has proven key to understanding disease ontogeny. However, limited information is available regarding the immunoglobulin (IG) gene repertoire in MM cases carrying different heavy chain
Glykeria Gkoliou, Glykeria Gkoliou, Andreas Agathangelidis, Georgos Karakatsoulis, Georgos Karakatsoulis, Chrysavgi Lalayanni, Apostolia Papalexandri, Alejandro Medina, Elisa Genuardi, Katerina Chlichlia, Evdoxia Hatjiharissi, Maria Papaioannou, Evangelos Terpos, Cristina Jimenez, Ioanna Sakellari, Simone Ferrero, Marco Ladetto, Ramon Garcia Sanz, Chrysoula Belessi, Kostas Stamatopoulos, Kostas Stamatopoulos   +20 more
doaj   +1 more source

Therapeutic Apheresis in Nigeria: A Multi‐Center Summary of Abstracts From the Inaugural Nigerian Society for Apheresis Scientific Meeting

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye, Chimezie Okwuonu, Evelyn Idam, Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Zinnah Aloziem, Blossom Amamchukwu, Patience Elimia, Mkpoikanabasi Obot‐Obot, Henry Mbakwe, Praises Maduagwuna, Olatunji Akinrodoye, Chiamaka Anyanwu, Benjamin Anyanwu, Adedamola Akinsiku, Oluwatoyin A. Akinsiku, Muzamil O. Hassan, Fatiu A. Arogundade, Olalekan E. Ojo, Homayemem Weli, Jesupelumi Adenihun, Aderemi Adelaja, Ebun Bamgboye, Olalekan Olatise, Ade E. Faponle, Ayoola Odeyemi, Michael Muoka, Stephen Asaolu, Qudrat Busari, Blessing Dawudu, Michael Naiyeju, Rasheed A. Balogun   +33 more
wiley   +1 more source

An Atypical Immunoglobulin [PDF]

Blood, 1968
Abstract A protein of the Ig G family has been isolated from the serum of a patient with a tentative diagnosis of a plasma cell neoplasm. The protein has a lower sedimentation constant (5.4) and a lower molecular weight (125,000) than normal immunoglobulins of the G family.
A F, Lewis, D E, Bergsagel, A, Bruce-Robertson, R K, Schachter, G E, Connell   +4 more
openaire   +2 more sources

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source