Immunoglobulins and immunoglobulin subclasses in the elderly [PDF]
Background: Published data imply that adult concentrations are achieved for all Ig isotypes and plateau by 15--18 years of age. Recent data, however, suggest that these results are not applicable in the elderly. There are no equivalent data for IgG subclasses.
R J, Lock, D J, Unsworth
openaire +2 more sources
Gene conversion in human rearranged immunoglobulin genes [PDF]
Over the past 20 years, many DNA sequences have been published suggesting that all or part of the V<sub>H</sub> segment of a rearranged immunoglobulin gene may be replaced in vivo. Two different mechanisms appear to be operating. One of these
Darlow, J.M. +3 more
core +1 more source
Acute reduction in secretory immunoglobulin A following smoking cessation [PDF]
Smokers report an increase in upper respiratory infections in the early phase of stopping smoking. One possible cause is a depletion in secretory immunoglobulin A (S-IgA) which has been observed in one study.
Steptoe, A +6 more
core +2 more sources
Dynamic immunoglobulin responses to gut bacteria during inflammatory bowel disease
Aberrant immune responses against gut microbiota are thought to be key drivers of inflammatory bowel disease (IBD) pathogenesis. However, the extent and targets of immunoglobulin (Ig) A versus IgG responses to gut bacteria in IBD and its association with
Sunaina Rengarajan +7 more
doaj +1 more source
Primary vs. Secondary Antibody Deficiency: Clinical Features and Infection Outcomes of Immunoglobulin Replacement [PDF]
Secondary antibody deficiency can occur as a result of haematological malignancies or certain medications, but not much is known about the clinical and immunological features of this group of patients as a whole. Here we describe a cohort of 167 patients
Matthew Buckland (589995) +27 more
core +2 more sources
Effect of hand-held mobile phones on the parotid gland: A cross sectional study
Background: The mobile phones widely used today uses electromagnetic radiations for signal transmission. These radiations have been speculated to cause pathological changes, especially in the salivary glands.
G Jeevitha, G Anuradha
doaj +1 more source
Anaphylactoid Reactions Following Red Blood Cell Transfusion in a Patient with Previously Undiagnosed Immunoglobulin A Deficiency: Case Report [PDF]
A 73-year-old, 104 kg female patient was hospitalised for debulking and low anterior colon resection operations. Anaphylactoid symptoms devel-oped when administering erythrocyte suspension and fresh frozen plasma.
Tümay Uludağ Yanaral +7 more
core +1 more source
The immunoglobulin κ gene families of human and mouse: a cottage industry approach [PDF]
Some aspects of the work of our group on the human and mouse immunoglobulin κ genes are reviewed. The human κ locus contains a large duplication: a 600 kb C κ-proximal copy with 40 V κ genes is found in the close vicinity of a 440 kb C κ-distal copy with
Zachau, Hans G.
core +1 more source
Localization, analysis and evolution of transposed human immunoglobulin VK genes [PDF]
The localization of Vκ gene regions to chromosome 2, on which the κ locus is located, and to other chromosomes is described. The Vκ genes that have been transposed to other chromosomes are called orphons.
Klopstock, Thomas +6 more
core +1 more source
Identification of the ancestral killer immunoglobulin-like receptor gene in primates [PDF]
Background: Killer Immunoglobulin-like Receptors (KIR) are essential immuno- surveillance molecules. They are expressed on natural killer and T cells, and interact with human leukocyte antigens.
Penny Coggill +26 more
core +1 more source

