Results 51 to 60 of about 119,120,288 (262)

Development, certification, and use of a pharmacopoeial standard for the content of immunoglobulin A in human immunoglobulins for parenteral administration

open access: yesБиопрепараты: Профилактика, диагностика, лечение, 2023
Scientific relevance. The immunoglobulin A (IgA) impurity content in parenteral human immunoglobulins should be determined in accordance with the State Pharmacopoeia of the Russian Federation by kinetic nephelometry, radial immunodiffusion, or enzyme ...
A. V. Nechaev   +6 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Changes in IgA-targeted microbiota following fecal transplantation for recurrent Clostridioides difficile infection

open access: yesGut Microbes, 2021
Secretory immunoglobulin A (IgA) interacts with intestinal microbiota and promotes mucosal homeostasis. IgA-bacteria interactions are altered during inflammatory diseases, but how these interactions are shaped by bacterial, host, and environmental ...
Kelsey E Huus   +9 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Conditioning murine B cells for immunoglobulin A production In vitro [PDF]

open access: yes, 2012
The respiratory mucosa is continuously exposed to a myriad of pathogens and allergens that are inhaled during respiration. B cells of the immune system produce immunoglobulin A (IgA) that protects the respiratory mucosa from inhaled pathogens and ...
Goh, Wil
core  

Genomic Organization, Splice Variants and Expression of CGMl, a CD66-related Member of the Carcinoembryonic Antigen Gene Family [PDF]

open access: yes, 1993
The tumor marker carcinoembryonic antigen (CEA) belongs to a family of proteins which are composed of one immunogiobulin variable domain and a varying number of immunoglobulin constant-like domains.
Zimmermann, Wolfgang   +5 more
core   +2 more sources

Prognostic value of serum CRP, IgM and IgA levels in children with Mycoplasma pneumoniae and pleural effusion [PDF]

open access: yesJournal of Medical Biochemistry
Background: Mycoplasma pneumoniae pneumonia (MPP) is a common cause of community-acquired pneumonia in children, with pleural effusion (PE) as a recognised but challenging complication.
Guo Huiqing
doaj   +1 more source

The effect of basketball competition on resting level of Immunoglobulins in elite female basketball players [PDF]

open access: yesفیزیولوژی ورزش و فعالیت بدنی, 2010
This research aimed to investigate the effect of one period of first division basketball competitionon some immune system factors in elite female basketball players.
محمد فرامرزی   +2 more
doaj   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

open access: yesFEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park   +8 more
wiley   +1 more source

Respuesta inmune por anticuerpos en niños de hasta cinco años con enfermedades genéticas

open access: yesRevista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2020
Fundamento: la valoración inmunológica forma parte del tratamiento integral a los pacientes con enfermedades genéticas. Las deficiencias de anticuerpos representan las alteraciones inmunológicas más frecuentes.Objetivo: describir la respuesta de ...
Enelis Reyes-Reyes   +3 more
doaj  

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