Results 341 to 350 of about 22,234,982 (388)
Some of the next articles are maybe not open access.
Pediatrics In Review, 2019
1. Smita Goodman, DO* 2. Jessica Reid-Adam, MD* 1. *Icahn School of Medicine at Mount Sinai, New York, NY Immunoglobulin A nephropathy (IgAN) is the most common form of primary chronic glomerular disease worldwide. First described in 1968 by pathologist Jean Berger, it was regarded for many years as a benign condition.
Smita, Goodman, Jessica, Reid-Adam
openaire +4 more sources
1. Smita Goodman, DO* 2. Jessica Reid-Adam, MD* 1. *Icahn School of Medicine at Mount Sinai, New York, NY Immunoglobulin A nephropathy (IgAN) is the most common form of primary chronic glomerular disease worldwide. First described in 1968 by pathologist Jean Berger, it was regarded for many years as a benign condition.
Smita, Goodman, Jessica, Reid-Adam
openaire +4 more sources
Human hybrid immunoglobulin M containing immunoglobulin A
In Vitro Cellular & Developmental Biology, 1988Some hybridoma clones made by fusion of a human lymphoblastoid cell line, HO323 with human B lymphocytes, secreted not only IgA but also IgM-like immunoglobulin molecules. The IgM-like immunoglobulin had a molecular size of 900 K which corresponded to that of IgM. Immunochemical analyses revealed that the IgM-like immunoglobulin contained two monomeric
H, Shinmoto +4 more
openaire +2 more sources
2015
Abstract Immunoglobulin A (IgA) nephropathy is the most common primary glomerulonephritis. It runs a slow and sometimes relentless clinical course with consequent end-stage renal failure in 35–40% of patients 25–30 years after first clinical presentation.
Tang, SCW, Lai, KN
openaire +4 more sources
Abstract Immunoglobulin A (IgA) nephropathy is the most common primary glomerulonephritis. It runs a slow and sometimes relentless clinical course with consequent end-stage renal failure in 35–40% of patients 25–30 years after first clinical presentation.
Tang, SCW, Lai, KN
openaire +4 more sources
New England Journal of Medicine, 1968
ONE of the important recent advances in modern immunology is the recognition that antibody activity is associated with a group of multichain proteins of varying mobility and molecular size. Normal serum probably contains hundreds of different antibodies, each being individually specific in its sequence of amino acids.
openaire +2 more sources
ONE of the important recent advances in modern immunology is the recognition that antibody activity is associated with a group of multichain proteins of varying mobility and molecular size. Normal serum probably contains hundreds of different antibodies, each being individually specific in its sequence of amino acids.
openaire +2 more sources
Biochemical and Biophysical Research Communications, 1983
In an examination of 16 human immunoglobulin lambda-light chains, one was found to have amino acid substitutions which have not previously been reported for the constant region of the lambda-chains. It involved in two positions: an arginine instead of lysine at position 130, and a leucine for glutamine at position 195 (Sh numbering (1) ).
T, Shinoda +3 more
openaire +2 more sources
In an examination of 16 human immunoglobulin lambda-light chains, one was found to have amino acid substitutions which have not previously been reported for the constant region of the lambda-chains. It involved in two positions: an arginine instead of lysine at position 130, and a leucine for glutamine at position 195 (Sh numbering (1) ).
T, Shinoda +3 more
openaire +2 more sources
Serologic study of immunoglobulin A-fibronectin aggregates in immunoglobulin a nephropathy
American Journal of Kidney Diseases, 1996The immunoglobulin A (IgA)-fibronectin aggregates, detected by enzyme-linked immunosorbent assay using either antifibronectin or collagen I as binding protein, were previously found to be raised in the circulation of patients with IgA nephropathy (IgAN). It has been suggested that IgA-fibronectin aggregates are involved in the pathogenesis and that the
Kar Neng Lai +4 more
openaire +4 more sources
Secretory immunoglobulin A and immunoglobulin G in horse saliva
Veterinary Immunology and Immunopathology, 2016This study aimed to increase the knowledge on salivary antibodies in the horse since these constitute an important part of the immune defence of the oral cavity. For that purpose assays to detect horse immunoglobulin A (IgA) including secretory IgA (SIgA) were set up and the molecular weights of different components of the horse IgA system were ...
Anna-Karin E, Palm +3 more
openaire +2 more sources
Immunoglobulin subclasses and HLA alleles in immunoglobulin A deficiency
The Indian Journal of Pediatrics, 2003The term "IgA Deficiency (IgAD)" should be reserved for the individuals who do not have detectable disorders known to be associated with low IgA levels. IgG subclass deficiency or a lack of the IgG2 subclass that is specific against polysaccharide antigens, can be seen in many cases.Forty-five patients (27 males and 18 females; mean age 8.6 years ...
Oral, HALUK BARBAROS +5 more
openaire +3 more sources
Immunoglobulin A1 protease: A new therapeutic candidate for immunoglobulin A nephropathy
Nephrology, 2010ABSTRACTImmunoglobulin A nephropathy (IgAN), characterized by predominant or exclusive deposition of IgA1 in glomerular mesangium, is the most common primary glomerulonephritis worldwide. At present, the treatment is always limited due to the incomplete understanding of the pathogenesis of IgAN.
Lin-Shen, Xie +3 more
openaire +2 more sources
Comprehensive Physiology, 1991
Abstract The sections in this article are: Molecules Involved in Immunoglobulin a Transport Anatomic and Cellular Basis of Immunoglobulin a Response Immunoglobulin a Transport into ...
Stephen Holland +3 more
openaire +1 more source
Abstract The sections in this article are: Molecules Involved in Immunoglobulin a Transport Anatomic and Cellular Basis of Immunoglobulin a Response Immunoglobulin a Transport into ...
Stephen Holland +3 more
openaire +1 more source