Results 81 to 90 of about 812,706 (311)

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Effects of Feeding Probiotics on the Localization of Cells Containing Immunoreactive Interleukin-6 in the Intestine of Broiler Chicks

The Journal of Poultry Science, 2010
The aim of this study was to examine whether treatments of chicks with probiotics affect the population of cells containing interleukin-6 (IL-6) and IgA in the intestine of broiler chicks.
Yukinori Yoshimura, Miwa Oda, Naoki Isobe   +2 more
doaj   +1 more source

Immunoglobulin A glomerulonephropathy: A review

World Journal of Clinical Cases
In this editorial, we comment on the article by Meng et al published in the World Journal of Clinical Cases. We comprehensively review immunoglobulin A nephropathy (IgAN), including epidemiology, clinical presentation, diagnosis, and management.
El Labban, Mohamad, Surani, Salim
openaire   +2 more sources

RESPONS IMUNOGLOBULIN G (IgG) DAN IMUNOGLOBULIN M (IgM) AKIBAT LATIHAN SENAM PERNAFASAN [PDF]

This research aims at investigating the responses of immunoglobulin G and immunoglobulin M as the effects of breathing exercise. This is an experimental study using the pretest – posttest group design.
Prof. Dr., Jumhan Pida, M.Pd, Siswantoyo, Dr., M. Kes   +1 more
core  

Gene conversion in human rearranged immunoglobulin genes [PDF]

, 2006
Over the past 20 years, many DNA sequences have been published suggesting that all or part of the V_H segment of a rearranged immunoglobulin gene may be replaced in vivo. Two different mechanisms appear to be operating. One of these
A Martin, B Elliott, C-L Parng, CB Kobrin, CR Winstead, D Lenze, D Sehgal, David I. Stott, E Selsing, EJ Steenbergen, EJ Steenbergen, EJ Steenbergen, H Arakawa, H Zan, HF Tsai, IB Rogozin, IB Rogozin, JM Darlow, John M. Darlow, K Itoh, LJ Wysocki, M Reth, MR Lucier, MS Neuberger, N D’Avirro, N D’Avirro, PC Wilson, PD Weinstein, R Dildrop, R Kleinfield, R Rosenquist, R Wasserman, RC Beale, RS Becker, SJ Foster, U Krawinkel, V David, WT McCormack, Y Choi, Z Zhang, É Gontier   +40 more
core   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

Expression of interleukin 2 receptors on activated human B cells. [PDF]

, 1984
Using anti-Tac, a monoclonal anti-interleukin 2 (IL-2) receptor antibody, we have explored the possibility that certain activated B cells display receptors for IL-2.
Bongiovanni, KF, Depper, JM, Goldman, CK, Greene, WC, Korsmeyer, SJ, Leonard, WJ, Robb, RJ, Sharrow, SO, Waldmann, TA   +8 more
core  

Chimerization of antibodies by isolation of rearranged genomic variable regions by the polymerase chain reaction [PDF]

, 1991
We describe a new method for amplification, by polymerase chain reaction (PCR), of rearranged segments encoding the variable part of light and heavy chains of an antibody (Ab) from the chromosomal DNA of hybridoma cells for the chimerization ofAbs.
Kaluzab, Brigitte, Schwirzke, Marina, Weidle, Ulrich H., Weiss, Elisabeth H., Weissenhorn, Winfried   +4 more
core   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Immunoglobulin E. A new class of human immunoglobulin [PDF]

Immunochemistry, 1968
H H, Bennich, K, Ishizaka, S G, Johansson, D S, Rowe, D R, Stanworth, W D, Terry   +5 more
openaire   +5 more sources