Results 91 to 100 of about 32,470,234 (258)

Immunoglobulin-induced aseptic meningitis: a case report [PDF]

open access: yes, 2018
Background Immunoglobulin associated meningitis is a rare disease that mimics infectious meningitis. This is, to our knowledge, the first case of Immunoglobulin-associated meningitis described in a patient with Systemic Lupus Erythematosus and ...
Alves, J   +7 more
core   +2 more sources

Substantiation of the effectiveness of various materials for the treatment of pulpitis of deciduous teeth

open access: yesЭндодонтия Today, 2020
Aim. The purpose is to justify the effective and safe use of various materials for the treatment of pulpitis of temporary teeth by amputation methods. Materials and methods.
O. L. Shevchenko, A. A. Antonova
doaj   +1 more source

Soluble CD40 ligand can replace the normal T cell-derived CD40 ligand signal to B cells in T cell-dependent activation [PDF]

open access: yes, 1993
We have constructed a soluble chimeric fusion protein between the mouse CD8 alpha chain and the mouse CD40 T cell ligand. This protein binds to both human and mouse B cells.
Lane, P.   +11 more
core   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

Relationship Between Peripheral Blood Eosinophil Count, Tissue Eosinophil Dominance and Serum Specific Immunoglobulin E Levels with Primary Chronic Rhinosinusitis Phenotype [PDF]

open access: yesModern Medicine
Background: European Position Paper on Rhinosinusitis and Nasal Polyps (EPOS) 2020 proposed a novel primary chronic rhinosinusitis (CRS) phenotype classification.
Anna Mailasari Kusuma DEWI   +4 more
doaj   +1 more source

Recurrent blocked duct(s) in a mother with immunoglobulin A deficiency [PDF]

open access: yes, 2008
Secretory immunoglobulin A (sIgA) is the dominant immunoglobulin in human milk, and apart from the obvious contribution it makes towards the protection of the infant, sIgA may also form an important part of the defense of the mammary gland.
Fetherston, C.M.   +2 more
core  

Hyper-immunoglobulin E syndrome in a neonate: A case report [PDF]

open access: yes, 2013
Hyper-immunoglobulin E syndrome (Job syndrome) is a rare primary immunodeficiency with variable presentation,characterized by recurrent infections, facial dimorphism, eczema, scoliosis, joint hyper-extensibility, pathologic fractures,very high IgE (>2000
Hasan Balık   +4 more
core   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

open access: yesMolecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan   +8 more
wiley   +1 more source

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