Results 81 to 90 of about 32,470,234 (258)

A Multi-Center Study of the Prevalence and Characteristics of Eosinophilic Phenotype and High IgE Levels Among Chinese Patients with Severe Asthma [Corrigendum]

open access: yesJournal of Asthma and Allergy, 2023
Ko FWS, Wang JKL, Hui DSC, et al. J Asthma Allergy. 2023;16:173-182. The authors have advised there is an error in Table 1. Table 1 on Page 177, in the third-to-last row, data addressing Median (IQR) for Eosinophil count, cells/mm3 should read from 3.2 ...
Ko FWS   +7 more
doaj  

The Discovery of Immunoglobulin E and Its Role in Allergy

open access: yes, 2014
Immunoglobulin E (IgE) was discovered in 1967. Today, more than 40 years after the discovery, the normal beneficial function in the body of this enigmatic immunoglobulin still remains unclear.
S.G.O. Johansson, Johansson, SGO
core   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Omalizumab, an anti-immunoglobulin E antibody: state of the art

open access: yes, 2014
Cristoforo Incorvaia,1 Marina Mauro,2 Marina Russello,2 Chiara Formigoni,3 Gian Galeazzo Riario-Sforza,1 Erminia Ridolo41Allergy/Pulmonary Rehabilitation, Istituti Clinici di Perfezionamento Hospital, Milan, Italy; 2Allergy Unit, 3Scientific Library ...
Formigoni C   +11 more
core   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

Inflammation markers - Immunoglobulin E (IgE)

open access: yes
Inflammation markers, for instance C-reactive protein (CRP), Lymphocytes, Neopterin, Immunoglobulin E (IgE), Immunoglobulin G (IgG), and tissue Transglutaminase Immunoglobulin A (tTg-IgA), measured with traditional enzymatic tests, such as Enzyme-Linked ...
TRacking Adolescents' Individual Lives Survey
core   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

The role of immunological biomarkers in the pathogenesis of atopic bronchial asthma [PDF]

open access: yesPediatric Anesthesia and Critical Care Journal (PACCJ)
Introduction The identification of reliable biomarkers for bronchial asthma, particularly in pediatric patients, is a topic of growing interest. This is primarily due to diagnostic chal- lenges in children, including limited capabilities for pul- monary
T. T. Panahova
doaj   +1 more source

Acquiring maternal immunoglobulin: Different receptors, similar functions

open access: yes, 2004
The isolation of a novel Fc receptor (FcRY) from chicken yolk sac provides insight at the mechanistic level as to how avian maternal immunoglobulin (IgY) is transferred to offspring.
E.Sally Ward, Ward, E. Sally
core   +1 more source

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

open access: yesMolecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both   +7 more
wiley   +1 more source

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