Immunoglobulin E, Interleukin-18 and Interleukin-12 in Patients with Atopic Dermatitis: Correlation with Disease Activity [PDF]
Introduction: Atopic dermatitis (AD) is a chronic inflammatory skin disorder. Immunological/inflammatory reactions are reported to play a role in AD but their role in disease activity has not been fully investigated. This study was done to investigate
Khaled Zedan +6 more
doaj +1 more source
Analysis of immunoglobulin E-mediated responses in central Africa
Analysis of immunoglobulin E-mediated responses in central ...
Cenk Suphioglu (13063443)
core
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Unlocking the potential of cell‐permeable nanobodies for intracellular applications
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source
Serum IgE as a Biomarker of Severity and Short-term Treatment Response in Steroid-naïve Children with Asthma: A Hospital-based Prospective Study [PDF]
Introduction: Paediatric asthma is a growing public health challenge in Low- and Middle-Income Countries (LMICs), with increasing prevalence and substantial morbidity.
Kishore Alagesan +5 more
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Targeted therapy of bronchial asthma in children and adolescents: А narrative review
The aim. To evaluate the results of clinical studies on the efficacy and safety of bronchial asthma (BA) therapy with genetically engineered biologicals (GEBP) in children and adolescents.Materials and methods.
M. S. Matevosova +5 more
doaj +1 more source
Khalil Assiri,1 Jagadish Hosmani,1 Sandeepa Nuchilakath Chalikkandy,1 Abdullah M Alkahtani,2 Raghad Mohammed Alhanif,3 Sarah Ahmed Alsarh,3 Shankargouda Patil,4 Rodolfo Reda,5 Luca Testarelli5 1Department of Diagnostic Dental Sciences, College of ...
Assiri K +8 more
doaj
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source

