Results 211 to 220 of about 76,339 (318)

X-Ray Crystallographic Studies of the Fab and Fc Fragments of Human Myeloma Immunoglobulins

Cold Spring Harbor Symposia on Quantitative Biology, 1972
R J, Poljak, L M, Amzel, H P, Avey, L N, Becka, D J, Goldstein, R L, Humphrey   +5 more
openaire   +2 more sources

Generation and characterization of iPSC‐derived microglia for in vitro modeling of stimuli‐specific neuroimmune responses

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION Microglia are macrophage‐like brain resident immune cells known to express numerous Alzheimer's disease risk genes. Here we generated a human induced pluripotent stem cell (iPSC) derived microglia cell culture model for use in neuroimmune modeling and therapeutic testing.
Angela K. Haskell, Joshua A. Kulas, William E. Carter, June Javens‐Wolfe, Raven Dance Hinkel, Mustapha Moussaif, Jacob S. Smiley, Olivia Lazaro, Sylvia Robertson, Alan D. Palkowitz, Bruce T. Lamb, Timothy I. Richardson, Jeffrey L. Dage, Shaoyou Chu, Travis Johnson, Louis F. Stancato, Abdul Qadir Syed   +16 more
wiley   +1 more source

Development of a humanized anti-fibrin monoclonal antibody for the treatment of neuroinflammatory and retinal diseases. [PDF]

J Neuroinflammation
Kantor AB, Rickert M, Cheng H, Flanagan K, Salgotra V, Suppahia A, Ryu JK, Widboom PF, Warfield JR, Akassoglou K, Stavenhagen JB.   +10 more
europepmc   +1 more source

Single-domain antibodies for brain targeting [PDF]

, 2014
Lalatsa, Katerina, Moreira Leite, Diana
core   +1 more source

Spatial heterogeneity in microglia‐complement crosstalk: Implications for synaptic pruning in Alzheimer's disease

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract Alzheimer's disease (AD) is a neurodegenerative disorder characterized by synaptic loss, as a key pathological feature in its early stages. Recent studies have highlighted the central role of microglia–complement interactions in synaptic pruning.
Qiuyan Ye, Wei Gao, Jiaping Feng, Xue Li, Jianhui Li, Fengge Yang, Linqing Li, Mingsheng Zi, Xinkai Wu, Hainan Gao, Honglin Li   +10 more
wiley   +1 more source

Comparative In Vitro and In Vivo Evaluation of Anti-CCR8 Full-Sized IgG and Its Fab Fragments in Murine Colorectal Cancer Models. [PDF]

Molecules
Hu T, Jiao R, Allen KJH, Frank C, Malo ME, Dadachova E.   +5 more
europepmc   +1 more source

A Molecular Basis for Antibody Specificity Crystal Structures of IgE-Allergen and IgG-Hapten Complexes [PDF]

Niemi, Merja
core  

Bispecific Antibodies Versus Chimeric Antigen Receptor T‐Cell Therapy in Relapsed/Refractory Diffuse Large B‐Cell Lymphoma: A Comparative Narrative Review of Efficacy, Safety, and Accessibility

Cancer Medicine, Volume 15, Issue 2, February 2026.
ABSTRACT Introduction Diffuse large B‐cell lymphoma (DLBCL) is the most common subtype of non‐Hodgkin lymphoma, and despite advances in frontline therapies such as rituximab, cyclophosphamide, doxorubicin hydrochloride (hydroxydaunorubicin), vincristine sulfate (Oncovin), and prednisone, approximately 30%–40% of patients develop relapsed or refractory (
Dana Sofian Abou, Husna Irfan Thalib, Fayza Akil, Samia Zuhair Sabbagh, Hala Sofian Abou, Mable Pereira, Fatma ElSayed Hassan   +6 more
wiley   +1 more source

Selective decoupling of IgG1 binding to viral Fc receptors restores antibody-mediated NK cell activation against HCMV. [PDF]

Cell Rep
Qerqez AN, Hoffmann K, Lee AG, Pareek S, Hager K, Mishra AK, Delidakis G, Bentley K, Kerr-Jones L, Cabrera M, Nguyen T, Göttler RL, Chowdhury A, Kolb PL, Hengel H, Georgiou G, McLellan JS, Stanton RJ, Nguyen AW, Maynard JA.   +19 more
europepmc   +1 more source

Proteomic Analysis of Regulated Dendritic Cell Endosomes Reveals Dynamic Adaptation to Antigen Uptake and Cross‐Presentation

European Journal of Immunology, Volume 56, Issue 2, February 2026.
Phagocytosis of yeast activates recruitment of proteases and trafficking factors from the secretory and endosomal pathways to the IRAP compartment and subsequently phagosomes, promoting cross‐presentation. In the absence of Sec22b, IRAP endosome and phagosome maturation to late endosomes is accelerated.
Alice Senni, Louise Grumbach, Sara Ceccacci, Mathieu Frechin, Nicolas Goudin, Ida Chiara Guerrera, Barbara Bertocci, Peter van Endert   +7 more
wiley   +1 more source