Results 261 to 270 of about 76,339 (318)

IgC Fc fragments induce B cell differentiation and immunoglobulin secretion

Immunology Letters, 1989
We now show that the Fc fragment is capable of inducing B cell differentiation and secretion of immunoglobulins (Igs) in human mononuclear cells from peripheral blood (PBMC). The absolute number of plasma cells observed in all individuals tested is similar.
E D, Carosella, J, Armand
openaire   +2 more sources

Immunoglobulin M: Fixation of Human Complement by the Fc Fragment

Science, 1972
The Fc fragment [(Fc) 5 μ, with a molecular weight of 342,000] of human immunoglobulin M from patients with Waldenström's macroglobulinemia has a complement fixing ability approximately 19 times greater on a molar basis than that of the parent immunoglobulin M.
A G, Plaut, S, Cohen, T B, Tomasi
openaire   +2 more sources

Conjugates of Superoxide Dismutase with the Fc Fragment of Immunoglobulin G

The Journal of Biochemistry, 1991
We constructed conjugates of superoxide dismutase (SOD) and the Fc fragment of human immunoglobulin G. The lysyl residues of bovine erythrocyte Cu,Zn-SOD were covalently linked with cysteine residues of the Fc fragment using N-succinimidyl 4-(N-maleimido)-butylate as a crosslinking agent.
A, Zanma, Y, Matsumoto, Y, Masuho
openaire   +2 more sources

Fc Fragment of Immunoglobulin G in Normal Human Plasma and Urine

Nature, 1967
IT has been shown that immunoglobulins of low molecular weight (micro-immunoglobulins) in normal human urine (compare ref. 1) are predominantly composed of material which closely resembles light polypeptide chains2. This is also true of the micro-immunoglobulins in “post-exercise” urine3 and in urine from patients with connective tissue disease4. Micro-
I, Berggård, H, Bennich
openaire   +2 more sources

Ultrastructure of the Fc fragment of human immunonoglobulin G

Immunochemistry, 1971
Abstract Crystals of the plasmin Fc fragment of human immunoglobulin G have been examined in the electron microscope at various stages during dissociation and recrystallization. Two characteristic shapes are recognized in the micrographs. One is a double, concentric annulus in which the outer annulus is seen to consist of 12 masses disposed radially ...
L, Pinteric, R H, Painter, G E, Connell
openaire   +2 more sources

Characterization of the Fc′ Fragment of Immunoglobulin G in Normal Human Urine

Nature, 1969
A FRAGMENT in normal human urine related specifically to the heavy chains of immunoglobulin G (IgG) was found1 by gel diffusion and immunoelectrophoretic analysis to be antigenically similar to the Fc′ fragment produced by papain digestion of the IgG molecule.
M W, Turner, I, Berggård
openaire   +2 more sources

An improved protocol for large scale production of high purity ‘Fc’ fragment of human immunoglobulin G (IgG-Fc)

Journal of Chromatography B, 2020
We describe a simplified approach for purification and characterization of human 'IgG-Fc' fragment used widely as immunochemical tool and for therapeutic purposes. The 'Fc' fragment was purified from human IgG in a 3-stage column chromatography. The purified 'Fc' fragment appeared as a dimer glycoprotein with an apparent molecular mass of 52,981 Dalton
Jatin B, Tandale, Shamkant B, Badgujar, Babasaheb U, Tandale, Unmesh, Angre, Siddharth B, Daftary, Sanjeev, Lala, Vinod P, Gaur   +6 more
openaire   +2 more sources

Unsusceptibility of recombinant human Fc fragments of immunoglobulin E to thrombin

Human Antibodies, 1996
Human immunoglobulin E (IgE) contains a potential recognition sequence for thrombin protease cleavage at N-terminal end of Cε3 domain responsible for binding to α chain of high affinity Fc receptor for IgE (FcεRICα, but it remains unknown for the enzyme susceptibility.
openaire   +2 more sources

Effective treatment of experimental autoimmune neuritis with Fc fragment of human immunoglobulin

Journal of Neuroimmunology, 2007
IV immunoglobulin (IVIg) and its Fc fragment proved effective in preventing further progression of experimental autoimmune neuritis (EAN) in the rat induced by whole bovine peripheral nerve myelin and shortening disease duration. This effectiveness was associated with significant differences in electrophysiological parameters including less ...
Hsin Hsin, Lin, Min Xia, Wang, Judith M, Spies, John D, Pollard   +3 more
openaire   +2 more sources

Expression of Fc Fragment Receptors of Immunoglobulin G (Fc?Rs) in Rat Hepatic Stellate Cells

Digestive Diseases and Sciences, 2005
Hepatic stellate cells (HSCs) are now considered the major cell type in the liver mediating the development of liver fibrosis. Recently it was demonstrated that HSCs express membrane proteins involved in antigen presentation. We further evaluate immunological properties of HSCs by examining the expression and function of the Fc fragment of ...
Hong, Shen, Manna, Zhang, Kelly, Kaita, Gerald Y, Minuk, Julia, Rempel, Yuewen, Gong   +5 more
openaire   +2 more sources