Results 271 to 280 of about 732,598 (320)
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NMR assignments of the N-glycans of the Fc fragment of mouse immunoglobulin G2b glycoprotein
Biomolecular NMR Assignments, 2021The Fc portion of immunoglobulin G (IgG) promotes defensive effector functions in the immune system by interacting with Fcγ receptors and complement component C1q. These interactions critically depend on N-glycosylation at Asn297 of each CH2 domain, where biantennary complex-type oligosaccharides contain microheterogeneities resulting primarily from ...
Saeko Yanaka +6 more
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Expression of Fc Fragment Receptors of Immunoglobulin G (Fc?Rs) in Rat Hepatic Stellate Cells
Digestive Diseases and Sciences, 2005Hepatic stellate cells (HSCs) are now considered the major cell type in the liver mediating the development of liver fibrosis. Recently it was demonstrated that HSCs express membrane proteins involved in antigen presentation. We further evaluate immunological properties of HSCs by examining the expression and function of the Fc fragment of ...
Hong, Shen +5 more
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Immunochemistry, 1972
Abstract The major electrophoretic components of Fc prepared by plasmin digestion of human IgG ( γ 1 subclass) have been isolated and their physical, chemical and biological properties examined. The individual components showed the same amino acid composition, the same amino terminal residue, threonine, and were shown to have the same sedimentation
J O, Minta, R H, Painter
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Abstract The major electrophoretic components of Fc prepared by plasmin digestion of human IgG ( γ 1 subclass) have been isolated and their physical, chemical and biological properties examined. The individual components showed the same amino acid composition, the same amino terminal residue, threonine, and were shown to have the same sedimentation
J O, Minta, R H, Painter
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Bacterial Proteins and Their Proposed Interactions with Fc or Fab Fragments of Immunoglobulins
Biochemistry & Physiology: Open Access, 2014The reactivity of Immunoglobulin Binding Proteins (IBP) to Fc and/or Fab fragments of immunoglobulins was summarized in this review. Staphylococcal protein A (SpA), Streptococcal protein G and Peptostreptococcal protein L (SpL) were the IBP reported. SpA reacted with IgG from skunk, coyote, raccoon, mule and donkey.
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The binding of protein A of immunoglobulin G and of Fab and Fc fragments.
Acta pathologica et microbiologica Scandinavica. Section C, Immunology, 1979Results are presented to show that protein A (pA) may fix to the Fab region of IgG outside the antigen binding site. Thus, pA-reactive Fab fragments were isolated both from specific anti-egg albumin and specific anti-measles virus antibodies. A probable significance of this Fab reactivity in the precipitation reaction between IgG and pA is discussed ...
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Production of an Fc Fragment from Human Immunoglobulin a by an IgA-Specific Bacterial Protease
1974Enzymatic proteolysis of human immunoglobulin A yields Fabα fragments but the Fcα is degraded to small peptides. The unavailability of Fcα has hampered to some extent certain studies of IgA, e.g., its primary structure and the attachment site of secretory component and J chain.
A G, Plaut, R J, Genco, T B, Tomasi
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International Journal of Biological Macromolecules, 2017
A. Sidorov +5 more
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A. Sidorov +5 more
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[Isolation of FAB and Fc fragments from murine immunoglobulin G1].
Biulleten' eksperimental'noi biologii i meditsiny, 1979Two methods of isolating Fab- and Fc-fragments from mouse immunoglobulin G1 are presented. The first method involves fractionation of papain protein hydrolysate on a column with DEAE- (or DE-32)-cellulose adjusted with 0.005 M K-phosphate buffer, pH 8. The Fab-fragment was eluted from the column with the starting buffer.
E L, Beliaeva +2 more
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Zeitschrift für Immunitätsforschung: Immunobiology, 1978
Molecular weight determinations of immunoglobulin D suggest the presence of an extra region of the delta chain. In an attempt to locate this region, an IgDlambda myeloma protein (Gur), was digested with trypsin for 4 min at 56 degrees and the Fc fragment isolated by ion exchange chromatography.
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Molecular weight determinations of immunoglobulin D suggest the presence of an extra region of the delta chain. In an attempt to locate this region, an IgDlambda myeloma protein (Gur), was digested with trypsin for 4 min at 56 degrees and the Fc fragment isolated by ion exchange chromatography.
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