Establishment and biological characterization of radioresistant colorectal cancer cell lines
Under ionizing radiation exposure, radiation‐sensitive cancer cells exhibit oxidative stress and DNA damage, while radiation‐resistant cancer cells exhibit strong antioxidant properties and DNA damage repair. Radiotherapy resistance is a major cause of recurrence and metastasis in colorectal cancer (CRC).
Tian‐Yin Qu+10 more
wiley +1 more source
RESPONS IMUNOGLOBULIN G (IgG) DAN IMUNOGLOBULIN M (IgM) AKIBAT LATIHAN SENAM PERNAFASAN [PDF]
This research aims at investigating the responses of immunoglobulin G and immunoglobulin M as the effects of breathing exercise. This is an experimental study using the pretest – posttest group design.
Prof. Dr., Jumhan Pida, M.Pd+1 more
core
Characterisation of placental malaria in olive baboons (Papio anubis) infected with Plasmodium knowlesi H strain [PDF]
Pregnant women have increased susceptibility to malaria infection. In these women, malaria parasites are frequently found sequestered in the placental intervillous spaces, a condition referred to as placental malaria (PM). Placental malaria threatens the health of the mother and the child's life by causing still births and reduction in gestational age.
arxiv
Possible role of human ribonuclease dicer in the regulation of R loops
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik+2 more
wiley +1 more source
Practical recognition tools of immunoglobulin G serum antibodies against the myelin oligodendrocyte glycoprotein‐positive optic neuritis and its clinical implications [PDF]
Myelin oligodendrocyte glycoprotein (MOG)-associated disease is an autoimmune disease of the central nervous system, associated with the presence of immunoglobulin G serum antibodies against MOG.
Asseyer, Susanna+5 more
core +1 more source
Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies
This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal+8 more
wiley +1 more source
Two subtypes (types 1 and 2) of autoimmune pancreatitis (AIP) are currently recognized. Type 1 AIP is related to immunoglobulin G4 (lymphoplasmacytic sclerosing pancreatitis), and type 2 AIP is characterized by neutrophilic infiltration into the ...
doaj +1 more source
Abstract Purpose This study aims to evaluate the accuracy of the frameless linear accelerator‐based stereotactic radiosurgery (FSRS) system incorporating cone‐beam CT (CBCT), six degrees of freedom (6‐DoF) couch, room laser, and surface image‐guided (SG) systems.
Hao‐Wen Cheng+4 more
wiley +1 more source
Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns
Immunoglobulin G (IgG), a glycoprotein secreted by plasma B-cells, plays a major role in the human adaptive immune response and are associated with a wide range of diseases.
Annika Wahl+32 more
doaj +1 more source
Characterization of the Interaction between the Herpes Simplex Virus Type I Fc Receptor and Immunoglobulin G [PDF]
Herpes simplex virus type I (HSV-1) virions and HSV-1-infected cells bind to human immunoglobulin G (hIgG) via its Fc region. A complex of two surface glycoproteins encoded by HSV-1, gE and gI, is responsible for Fc binding.
Bjorkman, Pamela J.+5 more
core +1 more source