Results 121 to 130 of about 14,179,362 (304)

Glycosylation of immunoglobulin G determines osteoclast differentiation and bone loss

Nature Communications, 2015
Immunglobulin G (IgG) sialylation represents a key checkpoint that determines the engagement of pro- or anti-inflammatory Fcγ receptors (FcγR) and the direction of the immune response.
U. Harre, S. Lang, R. Pfeifle, Y. Rombouts, S. Frühbeißer, K. Amara, H. Bang, A. Lux, C. Koeleman, W. Baum, Katharina Dietel, F. Gröhn, V. Malmström, Lars Klareskog, G. Krönke, R. Kocijan, F. Nimmerjahn, R. Toes, M. Herrmann, H. Scherer, G. Schett   +20 more
semanticscholar   +1 more source

Recent Advances in the Diagnosis and Management of Autoimmune Pancreatitis: Similarities and Differences in Japan and Korea

Gut and Liver, 2013
Two subtypes (types 1 and 2) of autoimmune pancreatitis (AIP) are currently recognized. Type 1 AIP is related to immunoglobulin G4 (lymphoplasmacytic sclerosing pancreatitis), and type 2 AIP is characterized by neutrophilic infiltration into the ...
doaj   +1 more source

A common glycan structure on immunoglobulin G for enhancement of effector functions

Proceedings of the National Academy of Sciences of the United States of America, 2015
Significance Antibodies are important therapeutic agents and have been used for the treatment of many diseases, including infectious and inflammatory diseases, and cancer.
Chin-Wei Lin, M. Tsai, Shiou-Ting Li, Tsung-I Tsai, Kuo-Ching Chu, Ying-Chih Liu, M. Lai, Chia-Yu Wu, Yung-Chieh Tseng, Sachin S Shivatare, Chia-Hung Wang, Ping Chao, Shi-Yun Wang, H. Shih, Yi-fang Zeng, Tsai-Hong You, Jung-Yu Liao, Yu-Chen Tu, Yih‐Shyan Lin, Hong-Yang Chuang, Chia-Lin Chen, Charng-Sheng Tsai, Chiu-Chen Huang, N. Lin, Che Ma, Chung-Yi Wu, Chi-Huey Wong   +26 more
semanticscholar   +1 more source

Toxoplasma gondii immunoglobulin G in paired infant-and-mother sera

Paediatrica Indonesiana, 2009
Background  Toxoplasmosis  is  a worldwide zoonotic disease caused  by  Toxoplasma  gondii.  Congenital toxoplasmosis (CT) is  the  result  of  vertical transmission  during  pregnancy  that may cause pathologic effects  on  the newborn such  as ...
Ayling Sanjaya, Nurhayati Masloman, Rocky Wilar, Josef Tuda   +3 more
doaj   +1 more source

A wash-free, dip-type fiber optic plasmonic (DiP) assay for sub-zeptomole analyte detection [PDF]

arXiv, 2018
This study demonstrates a rapid, wash-free dip-type fiber optic plasmonic sandwich (DiP) assay capable of zeptomole analyte detection and 6-orders of wide dynamic range. The DiP assay is realized on a compact U-bent fiber optic probe surface by dipping the antibody functionalized probe into a mixture of sample solution and AuNP labeled reagent.
arxiv  

Changes in passively‐sensitized basophil activation to αS1‐casein after oral immunotherapy

Immunity, Inflammation and Disease, 2020
Introduction Immune response to cow's milk allergen (CMA) has been analyzed mostly using crude milk antigen or a mixture of various caseins. This study aimed to assess the changes in the immunological response against αS1‐casein during oral immunotherapy
Teruaki Matsui, Michihiro Naito, Kazunori Tagami, Iwao Tajima, Miyuki Teshigawara, Atsushi Makino, Katsumasa Kitamura, Yoshihiro Takasato, Shiro Sugiura, Chikako Yamada, Hidehiko Izumi, Ikuya Tsuge, Yasuto Kondo, Komei Ito   +13 more
doaj   +1 more source

Observation of plasmonic exceptional points [PDF]

arXiv, 2019
Non-Hermitian singularities known as exceptional-points (EPs) have been shown to exhibit increased sensitivities but the observation of EPs has so far been limited to wavelength scaled systems subject to diffraction limit. We propose a novel approach to EPs and report their first observation in plasmonics at room temperature.
arxiv  

Is perceived intolerance to milk and wheat associated with the corresponding IgG and IgA food antibodies? A cross sectional study in subjects with morbid obesity and gastrointestinal symptoms

BMC Gastroenterology, 2018
Background Serum IgG and IgA food antibodies have been used for dietary advice to subjects with gastrointestinal symptoms and perceived food intolerance, but the role of these antibodies in mediating intolerance is controversial.
Anne Stine Kvehaugen, Dag Tveiten, Per G. Farup   +2 more
doaj   +1 more source

Imaging markers of disability in aquaporin-4 immunoglobulin G seropositive neuromyelitis optica: a graph theory study [PDF]

, 2019
Neuromyelitis optica spectrum disorders lack imaging biomarkers associated with disease course and supporting prognosis. This complex and heterogeneous set of disorders affects many regions of the central nervous system, including the spinal cord and ...
Asseyer, Susanna, Bellmann-Strobl, Judith, Brandt, Alexander U., Chien, Claudia, Kuchling, Joseph, Oertel, Frederike Cosima, Paul, Friedemann, Ruprecht, Klemens, Scheel, Michael, Siebert, Nadja, Zimmermann, Hanna   +10 more
core   +2 more sources

Comparison of methods for the analysis of therapeutic immunoglobulin G Fc-glycosylation profiles—Part 1: Separation-based methods

mAbs, 2014
Immunoglobulin G (IgG) crystallizable fragment (Fc) glycosylation is crucial for antibody effector functions, such as antibody-dependent cell-mediated cytotoxicity, and for their pharmacokinetic and pharmacodynamics behavior.
D. Reusch, Markus Haberger, B. Maier, M. Maier, Ronny Kloseck, B. Zimmermann, Michaela Hook, Z. Szabó, S. Tep, J. Wegstein, N. Alt, Patrick Bulau, M. Wuhrer   +12 more
semanticscholar   +1 more source