Glycosylation of the immunoglobulin G (IgG)-Fc tail is required for binding to Fc-gamma receptors (FcγRs) and complement-component C1q. A variety of IgG1-glycoforms is detected in human sera.
G. Dekkers +17 more
semanticscholar +1 more source
Surface plasmon resonance imaging detection of silver nanoparticle-tagged immunoglobulin [PDF]
This article is available open access through the publisher’s website at the link below. Copyright @ 2011 The Royal Society.The detection sensitivity of silver nanoparticle (AgNP)-tagged goat immunoglobulin G (gIgG) microarrays was investigated by ...
Asim K. Ray +6 more
core +1 more source
Host immunoglobulin G selectively identifies pathobionts in pediatric inflammatory bowel diseases
Inflammatory bowel diseases (IBD) are a group of complex and multifactorial disorders with unknown etiology. Chronic intestinal inflammation develops against resident intestinal bacteria in genetically susceptible hosts.
H. Armstrong +17 more
semanticscholar +1 more source
Parameters of the attenuated schistosome vaccine evaluated in the olive baboon [PDF]
Five exposures of baboons to the attenuated schistosome vaccine gave greater protection than three exposures, but this attenuation was not sustained when challenge was delayed.
Coulson, P.S. +7 more
core +3 more sources
Novel Concepts of Altered Immunoglobulin G Galactosylation in Autoimmune Diseases
The composition of the conserved N297 glycan in immunoglobulin G (IgG) has been shown to affect antibody effector functions via C1q of the complement system and Fc gamma receptors (FcγR) on immune cells.
G. Dekkers, T. Rispens, G. Vidarsson
semanticscholar +1 more source
Stressful life events are associated with low secretion rates of immunoglobulin A in saliva in the middle aged and elderly [PDF]
Whether chronic stress experience is related to down-regulation of secretory immunoglobulin A (S-IgA) was tested in two substantial cohorts, one middle-aged (N = 640) and one elderly (N = 582), comprising similar numbers of men (N = 556) and women (N ...
Phillips, A.C. +13 more
core +1 more source
Correlation between parity and concentration of immunoglobulins A, G and M in human colostrum [PDF]
Objective: To study the relationship between parity andimmunoglobulin concentrations in human colostrum. Methods:82 puerperas aged 21-41 years were selected, with gestationalage ≥ 37 weeks, up to the fourth parity, good nutritional status andno ...
Gabriel André João Striker +2 more
doaj
Ischemic stroke is associated with the pro-inflammatory potential of N-glycosylated immunoglobulin G
Glycosylation significantly affects protein structure and function and thus participates in multiple physiologic and pathologic processes. Studies demonstrated that immunoglobulin G (IgG) N-glycosylation associates with the risk factors of ischemic ...
Di Liu +13 more
semanticscholar +1 more source
Purification of rabbit polyclonal immunoglobulin G using anion exchangers. [PDF]
Negative chromatography antibody purification (N-CAP) using the weak anion exchanger STREAMLINE™ DEAE to extract impurities while retaining the target antibody is proposed as an effective method for the recovery of antibody from rabbit serum. The effects
Ling, Tau Chuan +5 more
core +1 more source
The changes of immunoglobulin G N-glycosylation in blood lipids and dyslipidaemia
Alternative N-glycosylation has significant structural and functional consequences on immunoglobulin G (IgG) and can affect immune responses, acting as a switch between pro- and anti-inflammatory IgG functionality.
Di Liu +14 more
semanticscholar +1 more source

