Results 61 to 70 of about 816,583 (359)
Molecular Oncology, EarlyView.High‐grade serous ovarian cancer (HGSOC) is the most common and aggressive type of ovarian cancer with urgent need for new treatment strategies. This study evaluates plasma‐activated media (PAM) as a novel treatment for HGSOC, showing its ability to selectively induce oxidative stress and apoptosis in HGSOC cell lines, patient ascites cells and primary
Lorena T. Davies +9 more
wiley +1 more source
Intrathecal immunoglobulin A and G antibodies to synapsin in a patient with limbic encephalitis [PDF]
, 2015 To report on the identification of intrathecally synthesized immunoglobulin A (IgA) and immunoglobulin G (IgG) antibodies to synapsin, a synaptic vesicle-associated protein, in a patient with limbic ...
Ahnert Hilger, Gudrun +11 more
core +2 more sources
Crowding-Regulated Binding of Divalent Biomolecules [PDF]
Phys. Rev. Lett. 130, 258401 (2023)Macromolecular crowding affects biophysical processes as diverse as diffusion, gene expression, cell growth, and senescence. Yet, there is no comprehensive understanding of how crowding affects reactions, particularly multivalent binding. Herein, we use scaled particle theory and develop a molecular simulation method to investigate the binding of ...
arxiv +1 more source
Molecular Oncology, EarlyView.Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad +13 more
wiley +1 more source
Use of intravenous immunoglobulin in neonates with haemolytic disease and immune thrombocytopenia [PDF]
, 2013 Background/Aim. Intravenous immunoglobulin is a blood product made of human polyclonal immunoglobulin G. The mode of action of intravenous immunoglobulin is very complex.
Janković Borisav +4 more
core +1 more source
Molecular Oncology, EarlyView.CD226+CD8+ T cells express elevated levels of RUNX2, exhibit higher proliferation capacity, cytokines and cytolytic molecules expression, and migratory capacity. In contrast, CD226−CD8+ T cells display an exhausted phenotype associated with the increased expression of co‐inhibitory receptors and impaired effector functions.
Maryam Rezaeifar +4 more
wiley +1 more source
Fetal alloimmune thrombocytopenia and maternal intravenous immunoglobulin infusion
Haematologica, 2010 Background Different therapeutic approaches have been used in fetal-neonatal alloimmune thrombocytopenia, but many centers administer immunoglobulin G infusions to the pregnant woman.
Günther Giers +5 more
doaj +1 more source
The effect of rituximab therapy on immunoglobulin levels in patients with multisystem autoimmune disease. [PDF]
, 2014 BACKGROUND: Rituximab is a B cell depleting anti-CD20 monoclonal antibody. CD20 is not expressed on mature plasma cells and accordingly rituximab does not have immediate effects on immunoglobulin levels.
Burns, Stella +8 more
core +2 more sources
BIMCV COVID-19+: a large annotated dataset of RX and CT images from COVID-19 patients [PDF]
arXiv, 2020 This paper describes BIMCV COVID-19+, a large dataset from the Valencian Region Medical ImageBank (BIMCV) containing chest X-ray images CXR (CR, DX) and computed tomography (CT) imaging of COVID-19+ patients along with their radiological findings and locations, pathologies, radiological reports (in Spanish), DICOM metadata, Polymerase chain reaction ...
arxiv
Why a diffusing single-molecule can be detected in few minutes by a large capturing bioelectronic interface [PDF]
arXiv, 2022 Single-molecule detection at a nanometric interface in a femtomolar solution, can take weeks as the encounter rate between the diffusing molecule to be detected and the transducing nano-device is negligibly small. On the other hand, several experiments prove that macroscopic label-free sensors based on field-effect-transistors (FET), engaging ...
arxiv