Results 91 to 100 of about 16,771 (215)
Nanogel‐Mediated Immunotherapy to Tackle Cancer and Inflammatory Diseases
ChemistryEurope, EarlyView.Nanogels formed through self‐assembly, microemulsion, or precipitation polymerization method enable precise delivery of immunotherapeutic factors and immune cell targeting, thus effectively modulating immune responses. This review highlights recent advances in stimuli‐responsive nanogel design, underlying mechanisms, and their potentials to tackle ...
Ziwen Zhang +7 more
wiley +1 more source
Ultrathin Al2O3‐Coated Biomass Carbon for Sodium‐Ion Batteries via a Synergistic Storage Mechanism
Carbon Energy, EarlyView.An ultrathin Al2O3 coating on biomass‐derived carbon effectively passivates surface defects, stabilizes the SEI, and enables a synergistic “adsorption–intercalation–filling” sodium storage mechanism. This strategy delivers outstanding cycling stability, fast Na+ kinetics, and broad temperature adaptability, demonstrating strong potential for practical ...
Junjun Zhou +13 more
wiley +1 more source
Post‐LECA Origin and Diversification of an Axonemal Outer Arm Dynein Motor
Cytoskeleton, EarlyView.ABSTRACT Dyneins were present in the last eukaryotic common ancestor (LECA) and play key roles in eukaryotic biology. Axonemal dyneins form the inner and outer arms that power ciliary beating, and it has long been recognized that outer arms in some organisms contain two different heavy chain motors, whereas those from other species contain a third unit
Stephen M. King
wiley +1 more source
Cancer Nexus, EarlyView.Mechanisms of resistance to cancer immunotherapy from a host–tumor interaction perspective. The central tumor cell is protected by multiple resistance mechanisms, including genetic mutations, epigenetic modifications, and metabolic alterations. The immunosuppressive tumor microenvironment features myeloid‐derived suppressor cells (MDSCs), regulatory T ...
Mohammed Elmujtba Adam Essa +2 more
wiley +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Verekitug, a novel, high‐affinity, fully human monoclonal antibody targeting thymic stromal lymphopoietin receptor (TSLPR), is in development as a potential treatment for severe asthma, chronic rhinosinusitis with nasal polyps (CRSwNP), and chronic obstructive pulmonary disease (COPD).
Dave Singh +9 more
wiley +1 more source
Immunoglobulin gamma 2b transgenes inhibit heavy chain gene rearrangement, but cannot promote B cell development. [PDF]
, 1993 Patricia Roth +5 more
openalex +1 more source
ESC Heart Failure, Volume 12, Issue 2, Page 942-954, April 2025.Abstract The immune system has long been recognized as a key driver in the progression of heart failure (HF). However, clinical trials targeting immune effectors have consistently failed to improve patient outcome across different HF aetiologies. The activation of the immune system in HF is complex, involving a broad network of pro‐inflammatory and ...
Johann Roessler +4 more
wiley +1 more source