Results 131 to 140 of about 218 (190)

Evidence for a Modulatory Effect of a 12‐Week Pomegranate Juice Intervention on the Transcriptional Response in Inflammatory Bowel Disease Patients Reducing Fecal Calprotectin Levels: Findings From a Proof‐of‐Principle Study

open access: yesMolecular Nutrition &Food Research, EarlyView.
This study investigated how pomegranate juice affects inflammation in patients with inflammatory bowel disease who are currently in remission. After 12 weeks of drinking pomegranate juice, patients showed reduced markers of intestinal inflammation.
Ilaria Minato   +25 more
wiley   +1 more source

Heat Sterilizable Coatings Based on Nafion and Graphene Quantum Dots With Advanced Antibacterial Performance

open access: yesNano Select, EarlyView.
Electrostatically assembled layer‐by‐layer waterborne nanocoatings comprising negatively charged Nafion and positively charged imidazole modified‐graphene quantum dots can inhibit the growth of bacteria and can withstand dry heat sterilization without any decline in their activity.
Mohammed Suleman Beg   +6 more
wiley   +1 more source

Downregulation of forkhead box O1 (FOXO1) acetylation ameliorates cognitive dysfunction by inhibiting endoplasmic reticulum stress‐regulated neuronal apoptosis in APP/PS1 transgenic mice

open access: yesNeuroprotection, EarlyView.
Downregulation of the expression of silent information regulator sirtuin 1 (SIRT1) exacerbates neuronal degeneration and loss by activating forkhead box O1 (FOXO1) acetylation and promoting endoplasmic reticulum stress (ERSA)‐mediated apoptosis in aging.
Nan Zhang   +20 more
wiley   +1 more source

Urinary Proteomics and Systems Biology Link Eight Proteins to the Higher Risk of Hypertension and Related Complications in Blacks Versus Whites

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Blacks are more prone to salt‐sensitive hypertension than Whites. This cross‐sectional analysis of a multi‐ethnic cohort aimed to search for proteins potentially involved in the susceptibility to salt sensitivity, hypertension, and hypertension‐related complications.
De‐Wei An   +22 more
wiley   +1 more source

Angelica dahurica Polysaccharides Ameliorate Colitis by Reducing the Restriction of Gut Microbiota‐Derived Imidazole Propionate on PPAR‐γ Signaling Activation

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Angelica dahurica radix (ADR), the root of the botanical family Apiaceae (genus Angelica, species Angelica dahurica (Hoffm.)), has been used to treat colitis in clinical practice. The immunomodulatory effects of ADR are attributed to its polysaccharides (RP). However, its mechanism of action has not been elucidated.
Jingyi Hu   +7 more
wiley   +1 more source

Treatment strategy for systemic lupus erythematosus using belimumab as indicated by multi‐omics analysis

open access: yesRheumatology &Autoimmunity, EarlyView.
Recent multi‐omics studies have demonstrated that belimumab specifically targets naïve B cells and a subset of memory B cells. This observation is consistent with belimumab's established efficacy and safety profile. Abstract Belimumab is an antibody targeting the cytokine B‐cell activating factor (BAFF), which is crucial for B cell differentiation, and
Keishi Fujio   +5 more
wiley   +1 more source

Addressing Climate Change and Advancing Green Development: Regional Transition Mechanisms for a Sustainable Future in Belt and Road Initiative Nations

open access: yesSustainable Development, EarlyView.
ABSTRACT This study examines the impact of regional transition and multilateral cooperation mechanisms on green development (GD) and climate change mitigation across 64 Belt and Road Initiative (BRI) partner nations (21 Asia, 22 Europe, 21 Africa and Middle East) from 2006 to 2021.
Atta Ullah   +3 more
wiley   +1 more source

The Biomaterial and Blood Clot Complex: A Crucial Early Environment for Osteo‐Coagulo‐Immunomodulation and the Advancement of Bone Biomaterials

open access: yesSmall Structures, EarlyView.
Various properties of bone biomaterials can modulate components of the blood clot (including the fibrin network, red blood cells, platelets, and the complement system) in vivo implantation, leading to the formation of a biomaterial–blood clot complex (BBCC) significantly impacting subsequent osteoimmunomodulation.
Zongpu Han   +11 more
wiley   +1 more source

CRISPR/Cas9‐edited tumor‐associated immune cells in cancer immunotherapy

open access: yesVIEW, EarlyView.
Abstract Immuno‐oncology represents an emerging field that has significantly transformed tumor therapeutics, with immune cells serving as the cellular foundations of cancer immunotherapy. Due to its high efficiency and sensitivity, CRISPR/Cas9 genome editing is a highly promising technique for precise and rapid gene modification.
Yuhui Ma   +6 more
wiley   +1 more source

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