Falsely abnormal serum protein electrophoresis after administration of intravenous immunoglobulins (IVIG): A retrospective cohort study. [PDF]
Pract Lab MedSulaiman A, Caturegli P.
europepmc +1 more source
CALB1 and RPL23 Are Essential for Maintaining Oocyte Quality and Function During Aging
Aging Cell, Volume 24, Issue 5, May 2025.This study investigates the mechanisms of oocyte aging in mice, identifying Calb1 and Rpl23 as key genes involved in calcium ion homeostasis and mitochondrial function. Knockdown of these genes led to mitochondrial dysfunction, meiotic defects, and spindle assembly abnormalities, while their overexpression partially rescued age‐related oocyte defects ...
Yingxue Han +6 more
wiley +1 more source
Longevity Humans Have Youthful Erythrocyte Function and Metabolic Signatures
Aging Cell, Volume 24, Issue 5, May 2025.Longevity humans have “a youthful erythrocyte function and metabolism” with a youth‐like oxygen release and anti‐oxidative capability to combat tissue hypoxia and improve healthspan. ABSTRACT Longevity individuals have lower susceptibility to chronic hypoxia, inflammation, oxidative stress, and aging‐related diseases.
Fang Yu +17 more
wiley +1 more source
A case report of biclonal immunoglobulin D lambda/lambda multiple myeloma in patient with liver echinococcosis. [PDF]
Biochem Med (Zagreb)Prce A +10 more
europepmc +1 more source
Aging Cell, Volume 24, Issue 5, May 2025.Age‐related differences in EAE outcomes stem from combined peripheral and CNS factors. Key peripheral adaptive immunity changes include altered naïve/memory T cell ratios, Th1 skewing, increased suppressive Tregs, CD4+ T cell exhaustion, enhanced B cell antigen presentation, and reduced NK cell cytotoxicity.
María Dema +6 more
wiley +1 more source
Identification of fibrinogen Aα-chain as an amyloid precursor protein in a case of canine coronary artery amyloidosis. [PDF]
J Vet Diagn InvestIwaide S +9 more
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Immunosenescence Profile Is Associated With Increased Susceptibility to Severe COVID‐19
Aging Cell, EarlyView.(A) A previous immunosenescence profile in individuals infected with SARS‐CoV2 creates a permissive environment for progression to severe COVID‐19: higher inflammaging, accumulation of exhausted/senescent T cells, an oligoclonal B‐cell repertoire, and accelerated epigenetic age.
Lucas Haniel A. Ventura +40 more
wiley +1 more source
Understanding IgM Structure and Biology to Engineer New Antibody Therapeutics. [PDF]
BioDrugsBuchner J, Sitia R, Svilenov HL.
europepmc +1 more source
DLK/JNK3 Upregulation Aggravates Hair Cell Senescence in Mice Cochleae via Excessive Autophagy
Aging Cell, EarlyView.In normal physiological processes, autophagy acts as a protective factor against aging stress. With the stress increase, the DLK/JNK3 pathway is activated and autophagy is continuously upregulated. In our study, excessive autophagy leads to hair cell senescence, which reveals that excessive autophagy can play a harmful role in senescence under certain ...
Rui Ding +8 more
wiley +1 more source