Results 11 to 20 of about 43,330 (313)

Specific activation and targeting of cytotoxic lymphocytes through chimeric single chains consisting of antibody-binding domains and the gamma or zeta subunits of the immunoglobulin and T-cell receptors.

Proceedings of the National Academy of Sciences of the United States of America, 1993
Zelig Eshhar, Tova Waks, G. Gross, Daniel Schindler   +3 more
exaly   +2 more sources

Identification of a gene locus for gamma-G-1 immunoglobulin H chains and its linkage to the H chain chromosome region in the mouse.

Proceedings of the National Academy of Sciences of the United States of America, 1967
John D Minna
exaly   +3 more sources

Diagnosing a Challenging Case of Primary Amyloidosis using Capillary Electrophoresis [PDF]

National Journal of Laboratory Medicine, 2021
Amyloid Light chain (AL) amyloidosis is characterised by deposition of intact free light chains or their fragments in extracellular space. Here, authors describe the journey of a diagnostically challenging patient who presented with features of ...
rashmi verma, rajni saijpaul, Surbhi Garg, niharika jain, Vineeta V Batra   +4 more
doaj   +1 more source

Expression of mu and gamma immunoglobulin heavy chains in different cells of a cloned mouse lymphoid line. [PDF]

Proceedings of the National Academy of Sciences of the United States of America, 1981
Peter D Burrows
exaly   +2 more sources

Pattern of serum immunoglobulins and free light chain levels among patients diagnosed with multiple myeloma in Southeast Nigeria

International Journal of Medicine and Health Development, 2023
Background: Abnormal plasma cells in multiple myeloma produce excessive amounts of immunoglobulins and free light chains, of which certain patterns predict patient survival.
Ifeyinwa D Nnakenyi, Anazoeze J Madu, Ifeoma C Ajuba, Sunday Ocheni, Gladys U Ilechukwu, Nnenna Ogbodo, Oji A Nnachi   +6 more
doaj   +1 more source

Chicken immunoglobulin gamma-heavy chains: limited VH gene repertoire, combinatorial diversification by D gene segments and evolution of the heavy chain locus.

EMBO Journal, 1988
Yigal Burstein
exaly   +3 more sources

Discrete analysis of camelid variable domains: sequences, structures, and in-silico structure prediction [PDF]

PeerJ, 2020
Antigen binding by antibodies requires precise orientation of the complementarity- determining region (CDR) loops in the variable domain to establish the correct contact surface.
Akhila Melarkode Vattekatte, Nicolas Ken Shinada, Tarun J. Narwani, Floriane Noël, Olivier Bertrand, Jean-Philippe Meyniel, Alain Malpertuy, Jean-Christophe Gelly, Frédéric Cadet, Alexandre G. de Brevern   +9 more
doaj   +2 more sources

Immune subtraction for improved resolution in serum protein immunofixation electrophoresis and antibody isotype determination in a patient with autoantibody

Practical Laboratory Medicine, 2021
Heavy chain isotypes of low level monoclonal immunoglobulins are sometimes obscured in serum immunofixation electrophoresis (SIFE) by a heavy background of polyclonal immunoglobulins.
Asad Ullah, Nivin Omar, Natasha M. Savage, Roni J. Bollag, Gurmukh Singh   +4 more
doaj   +1 more source

A Case of Primary Amyloidosis Involving Liver, Stomach, Intestines, and Heart without Evident Kidney Involvement

Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2022
Aim. Systemic amyloidosis caused by the synthesis and deposition of immunoglobulin light chains (AL amyloidosis) is a relatively rare disease that involves heart, kidneys, peripheral nervous system, gastrointestinal tract, and has a large number of ...
L. S. Kholopov, N. B. Gubegrits, O. A. Dyadyk, Yu. E. Chirkov, Yu. V. Tsohoyeva   +4 more
doaj   +1 more source

Tailor-making a protein a-derived domain for efficient site-specific photocoupling to Fc of mouse IgG₁. [PDF]

PLoS ONE, 2013
Affinity proteins binding to antibody constant regions have proved to be invaluable tools in biotechnology. Here, protein engineering was used to expand the repertoire of available immunoglobulin binding proteins via improvement of the binding strength ...
Feifan Yu, Peter Järver, Per-Åke Nygren   +2 more
doaj   +1 more source