Results 191 to 200 of about 39,915 (240)

AL amyloidosis with elevated peripheral blood cell counts - A frequent association with liver involvement. A single-center retrospective study. [PDF]

Leuk Res Rep
Ziarkiewicz M, Szczygieł J, Legatowicz-Koprowska M, Drozd-Sokołowska J, Boguradzki P, Jamroziak K, Basak G.   +6 more
europepmc   +1 more source

The Direct and Indirect Role of IgE on Airway Epithelium in Asthma

Allergy, Volume 80, Issue 4, Page 919-931, April 2025.
ABSTRACT Asthma is a chronic airway inflammatory disorder, affecting over 350 million people worldwide, with allergic asthma being the most common form of the disease. Allergic asthma is characterized by a type 2 (T2) inflammatory response triggered by numerous allergens beginning in the airway epithelium, which acts as a physical barrier to allergens ...
Christian Domingo, William W. Busse, Nicola A. Hanania, Muyesser Ertugrul, Lauren A. Millette, Tina Maio‐Twofoot, Xavier Jaumont, Oscar Palomares   +7 more
wiley   +1 more source

Post-Transplant Lymphoproliferative Disorder Manifesting as Lymphoplasmacytic Lymphoma Accompanying With Hemophagocytic Lymphohistiocytosis. [PDF]

J Hematol
Armatys A, Wozniczka K, Koclega A, Spalek A, Wlodarczyk M, Helbig G.   +5 more
europepmc   +1 more source

Echinococcus granulosus antigen B regulates T‐cell function through inhibition of signal transducer and activator of transcription 3 in experimental immune thrombocytopenia

British Journal of Haematology, EarlyView.
During the pathological process of immune thrombocytopenia, signal transducer and activator of transcription 3 (STAT3) is activated by JAKs, leading to the production of a large number of inflammatory cytokines and promoting the activation of Th1, Th2 and Th17 cells.
Yingbin Yue, Yunfei Zhang, Yongfeng Cheng, Hongjie Jiao, Mei Yan   +4 more
wiley   +1 more source

Primary giant mucosa-associated lymphoid tissue lymphoma of the lower lip: a case report and literature review. [PDF]

BMC Oral Health
Al-Aroomi MA, Baihua L, Chen J, Li N, Jiang C, Wang J.   +5 more
europepmc   +1 more source

Protein tyrosine phosphatases as emerging targets for cancer immunotherapy

British Journal of Pharmacology, EarlyView.
Abstract Contemporary strategies in cancer immunotherapy, despite remarkable success, remain constrained by inherent limitations such as suboptimal patient responses, the emergence of drug resistance, and the manifestation of pronounced adverse effects. Consequently, the need for alternative strategies for immunotherapy becomes clear.
Zihan Qu, Jiajun Dong, Zhong‐Yin Zhang
wiley   +1 more source

Rapidly Progressive Glomerulonephritis Secondary to Immunoglobulin M-associated Monoclonal Gammopathy of Renal Significance: A Report of a Rare Case. [PDF]

Cureus
Prieto-Torres AE, Rodriguez-Peralta DH.
europepmc   +1 more source

Diatom triacylglycerol metabolism: from carbon fixation to lipid droplet degradation

Biological Reviews, EarlyView.
ABSTRACT Diatoms are a prominent microalgae family that has attracted interest for its production of molecules of biotechnological interest. Their fatty acid profile is rich in health‐beneficial omega‐3 eicosapentaenoic acid (EPA). Furthermore, under nutrient‐deprived conditions, many diatom species, notably Phaeodactylum tricornutum, Thalassiosira ...
Victor Murison, Josiane Hérault, Justine Marchand, Lionel Ulmann   +3 more
wiley   +1 more source

Serum Proteomic Markers in Patients with Systemic Sclerosis in Relation to Silica Exposure. [PDF]

J Clin Med
Freire M, Sopeña B, Bravo S, Spuch C, Argibay A, Estévez M, Pena C, Naya M, Lama A, González-Quintela A.   +9 more
europepmc   +1 more source

Novel Approach to Overcome Osimertinib Resistance Using Bromodomain and Extra‐Terminal Domain Inhibitors

Cancer Science, Volume 116, Issue 5, Page 1392-1404, May 2025.
Our study found that epigenetic changes, particularly histone modifications regulating FGF1, contribute to osimertinib resistance. Targeting these modifications with BET inhibitors may offer new therapeutic strategies. ABSTRACT Osimertinib, a third‐generation EGFR‐tyrosine kinase inhibitor, is the first‐line therapy for lung cancer harboring EGFR ...
Yosuke Miyashita, Ken Tajima, Kenta Izumi, Naohisa Matsumoto, Daisuke Hayakawa, Ikuko Takeda Nakamura, Isana Katayama, Adityo Wibowo, Hironari Matsuda, Wira Winardi, Bagus Radityo Amien, Yoichiro Mitsuishi, Fumiyuki Takahashi, Kohta Nakamura, Ken Uchibori, Noriko Yanagitani, Takuo Hayashi, Kazuya Takamochi, Kenji Suzuki, Ryohei Katayama, Kazuhisa Takahashi   +20 more
wiley   +1 more source