Results 261 to 270 of about 13,815 (280)

The membrane exons of the pseudo-γ-chain gene of the human immunoglobulin are apparently functional and highly homologous to those of the γ1 gene

Immunology Letters, 1991
Nucleotide sequences of the membrane exons of human immunoglobulin pseudo-gamma gene and gamma 1 chain cDNA were determined and compared. The sequences of the membrane exons of the pseudo-gamma gene had no defective mutations in the coding regions or the exon-intron boundaries.
Kazuo Kinoshita, Akira Shimizu, Tasuku Honjo   +2 more
openaire   +3 more sources

Cell surface immunoglobulin μ and γ chains of human lymphoid cells are of higher apparent molecular weight than their secreted counterparts

European Journal of Immunology, 1980
AbstractSelected human lymphoma‐derived and lymphoblastoid cell lines have been characterized and shown to be useful model systems for the expression of either cell surface Ig, or secretory Ig, or both simultaneously. Daudi and Raji cell lines were shown to express surface IgM with no secretion of IgM.
A. R. Williamson, Paul A. Singer
openaire   +3 more sources

Genetic polymorphism of immunoglobulin G in the mink. VI. A regulatory gene controlling the expression of the gamma-chain constant region allotype of mink immunoglobulin.

Experimental and clinical immunogenetics, 1991
We describe here the inheritance of H6, one of the six known allotypes of the gamma-chain constant region of mink immunoglobulin (IgG). H6 is not present in minor concentrations in the serum, and its phenotypic expression is stable. However, in offspring of some of (H6-)X(H6-) crosses.
I I, Fomicheva, , Volkova OYu
openaire   +1 more source

['Reverse' variant of follicular lymphoma with monoclonality of the immunoglobulin heavy chain and T cell receptor gamma chain genes].

[Rinsho ketsueki] The Japanese journal of clinical hematology, 2004
We report an unusual case of the 'reverse' variant of follicular lymphoma in which the nodules had central parts that stained dark and cuffs that stained pale. Because diagnosis was difficult relying only on formalin-fixed histopathology, we examined the cell surface markers and karyotype.
Yasufumi, Masaki, Dong Ling, Li, Kumiko, Shimoyama, Takanori, Kawanami, Toshihiro, Fukushima, Hiroshi, Kawabata, Noriyoshi, Ogawa, Yuji, Wano, Yuko, Hirose, Susumu, Sugai   +9 more
openaire   +1 more source

Human genes for the immunoglobulin gamma-chain (Gm) allotypes and for the T cell receptor alpha-chain are distantly linked or unlinked.

Experimental and clinical immunogenetics, 1991
Since the genes for two of the T cell receptor (TCR) chains (alpha and delta) and for the immunoglobulin (Ig) heavy chains (alpha, gamma, delta, epsilon and mu) are all on the long arm of human chromosome 14, it is of interest to determine if they are genetically linked and, if so, how strongly.
M J, Sheehy, C A, Emler, T W, Mak, J P, Pandey   +3 more
openaire   +1 more source

Studies on fd fragments of human immunoglobulins. III. Immunogenic properties of gamma chains, myeloma fd gamma, and myeloma fd1 alpha.

Scandinavian journal of immunology, 1975
Earlier studies on antisera against Fab of pooled human IgG and IgA myeloma proteins disclosed the presence of class-specific Fd antibodies, the demonstration of which required interaction of heavy and light chains. To extend our knowledge about the antigenic structure of the Fd fragment of human immunoglobulins, antisera were prepared in rabbits ...
J M, Zegers, R E, Ballieux, E, van Loghem   +2 more
openaire   +1 more source

[Gene rearrangements of immunoglobulin heavy chain (IgH) and T cell receptor gamma chain (TCR gamma) in non-Hodgkin's lymphomas detected by polymerase chain reaction ].

Zhonghua bing li xue za zhi = Chinese journal of pathology, 1994
Gene rearrangement and monoclonality have been detected in non-Hodgkin's lymphomas (NHLs). The semi-nested polymerase chain reaction (PCR) was performed to amplify IgH and the mixed PCR to TCR gamma gene rearrangements. Monoclonal band was observed in 77% of B-cell NHLs with IgH primers and 91% of T-cell NHLs with TCR gamma primers.
J Z, Zhang, L S, Yan
openaire   +1 more source

[Monoclonal analysis of immunoglobulin heavy chain and T-cell receptor gamma chain gene rearrangements in paraffin-embedded tissues from non-Hodgkin lymphoma patients].

Rinsho byori. The Japanese journal of clinical pathology, 2007
Gene rearrangement is an important diagnostic marker of malignant lymphoma, and rearrangements of the immunoglobulin heavy chain (IgH) and T-cell receptor gamma chain (TCRgamma) genes are useful markers for Band T-cell lymphoma, respectively. A polymerase chain reaction (PCR) can be used to analyze clonality in formalin-fixed paraffin-embedded ...
Eisuke, Shiozawa, Tadanori, Yamochi, Tomoko, Shiozawa, Toshiko, Yamochi, Masafumi, Takimoto, Hidekazu, Ota   +5 more
openaire   +1 more source

Murine myeloma immunoglobulin heavy-chain mRNA. Isolation, partial purification, and characterization of .gamma.1, .gamma.2a, .gamma.2b, .gamma.3, .mu., and .alpha. heavy-chain mRNAs

, 1979
Charles Faust, Isabel Heim, J.M. Moore
openalex   +1 more source

Variation and Homology in the Mu and Gamma Heavy Chains of Human Immunoglobulins

, 1971
Akira Shimizu, Claudine Paul, Heinz Köhler, Tomotaka Shinoda, Frank W. Putnam   +4 more
openalex   +1 more source