Results 271 to 280 of about 43,330 (313)

Cloning and characterization of cDNAs encoding four different canine immunoglobulin γ chains

Veterinary Immunology and Immunopathology, 2001
cDNAs encoding four different canine immunoglobulin G (caIgG) gamma chains were identified in this study. One of these IgG gamma chain cDNAs, (caIgG-A), represents 92.5% of the IgG gamma chain cDNAs in a dog spleen cell cDNA library; a second partial IgG gamma chain cDNA (caIgG-B) was also identified in the library. The other two IgG gamma chain cDNAs (
L, Tang, C, Sampson, M J, Dreitz, C, McCall   +3 more
openaire   +2 more sources

IMMUNOGLOBULIN GAMMA CHAINS OF A MONOTREME MAMMAL, THE ECHIDNA (TACHYGLOSSUS ACULEATUS): AMINO ACID COMPOSITION AND PARTIAL AMINO ACID SEQUENCE

International Journal of Immunogenetics, 1977
SUMMARYThe echidna represents the lowest stage in phytogeny at which molecules clearly homologous to IgG antibodies appear to occur. We provide evidence that a fraction of γ chains possess an unblocked N terminal sequence comparable to the VHIII sub‐group of human γ chains and that glycine is the C‐terminal residue. Statistical comparison of amino acid
J L, Atwell, J J, Marchalonis
openaire   +2 more sources

TWO SEPARATE NON‐IMMUNE INTERACTIONS BETWEEN STAPHYLOCOCCAL PROTEIN A AND IMMUNOGLOBULINS ARE MEDIATED BY STRUCTURES ON γ CHAINS

Acta Pathologica Microbiologica Scandinavica Series B: Microbiology, 1986
The present investigation was undertaken to determine whether the light or the heavy immunoglobulin chain is involved in the alternative, non‐immune F(ab')2‐mediated binding to staphylococcal protein A. Purified human polyclonal IgG was mildly reduced with dithiothreitol and alkylated with iodoacetamide.
M, Erntell, E B, Myhre, G, Kronvall
openaire   +2 more sources

Localization of Immunoglobulin G γ-Chain mRNA-Expressing Cells in the Oviduct of Laying and Diethylstilbestrol-Treated Immature Hens

General and Comparative Endocrinology, 2000
The purpose of this study was to determine the synthetic sites of IgG in the chicken oviduct by localizing IgG gamma-chain mRNA (IgGgamma mRNA)-expressing cells and the effects of estrogen on their population. Paraffin sections of oviducal tissues from laying hens (approximately 57 weeks old) and immature hens (approximately 16 weeks old) with or ...
W M, Zheng, J, Izaki, S, Furusawa, Y, Yoshimura   +3 more
openaire   +2 more sources

Presentation of ovalbumin internalized via the immunoglobulin-A Fc receptor is enhanced through Fc receptor γ-chain signaling

Blood, 2001
AbstractThe mechanism of enhanced presentation of ovalbumin (OVA) internalized as immunoglobulin A (IgA)–OVA via the IgA Fc receptor (FcαR) was analyzed by focusing on the role of the FcαR-associated γ chain. Comparison of B-cell transfectants expressing FcαR plus wild-type (WT) γ chain or γ chain in which the immunoreceptor tyrosine-based activation ...
L, Shen, M, van Egmond, K, Siemasko, H, Gao, T, Wade, M L, Lang, M, Clark, J G, van De Winkel, W F, Wade   +8 more
openaire   +2 more sources

Genetic polymorphism of immunoglobulin G in the mink. VI. A regulatory gene controlling the expression of the gamma-chain constant region allotype of mink immunoglobulin.

Experimental and clinical immunogenetics, 1991
We describe here the inheritance of H6, one of the six known allotypes of the gamma-chain constant region of mink immunoglobulin (IgG). H6 is not present in minor concentrations in the serum, and its phenotypic expression is stable. However, in offspring of some of (H6-)X(H6-) crosses.
I I, Fomicheva, , Volkova OYu
openaire   +1 more source

Vectors for Expression of Signal Peptide-Dependent Proteins in Baculovirus/Insect Cell Systems and Their Application to Expression and Purification of the High-Affinity Immunoglobulin Gamma Fc Receptor I in Complex with Its Gamma Chain

Molecular Biotechnology, 2017
Integral membrane proteins play a central role in various cellular functions and are important therapeutic targets. However, technical challenges in the overexpression and purification of membrane proteins often represent a limiting factor for biochemical and structural studies.
Le, Le T M, Nyengaard, Jens R, Golas, Monika M, Sander, Bjoern   +3 more
openaire   +2 more sources

The membrane exons of the pseudo-γ-chain gene of the human immunoglobulin are apparently functional and highly homologous to those of the γ1 gene

Immunology Letters, 1991
Nucleotide sequences of the membrane exons of human immunoglobulin pseudo-gamma gene and gamma 1 chain cDNA were determined and compared. The sequences of the membrane exons of the pseudo-gamma gene had no defective mutations in the coding regions or the exon-intron boundaries.
K, Kinoshita, A, Shimizu, T, Honjo
openaire   +2 more sources

Synthesis and assembly of immunoglobulins by malignant human plasmacytes. I. Myelomas producing gamma-chains and light chains.

The Journal of experimental medicine, 1971
Three basic patterns of gamma-globulin synthesis are described in malignant human plasmacytes: extreme unbalanced synthesis where only L chains are synthesized; unbalanced synthesis in which intact gammaG globulin and an excess of free L chains are synthesized and secreted; and balanced synthesis where H and L chains appear to be synthesized in ...
S, Zolla, J, Buxbaum, E C, Franklin, M D, Scharff   +3 more
openaire   +1 more source

Cell surface immunoglobulin μ and γ chains of human lymphoid cells are of higher apparent molecular weight than their secreted counterparts

European Journal of Immunology, 1980
AbstractSelected human lymphoma‐derived and lymphoblastoid cell lines have been characterized and shown to be useful model systems for the expression of either cell surface Ig, or secretory Ig, or both simultaneously. Daudi and Raji cell lines were shown to express surface IgM with no secretion of IgM.
P A, Singer, A R, Williamson
openaire   +2 more sources