Results 281 to 290 of about 43,330 (313)
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['Reverse' variant of follicular lymphoma with monoclonality of the immunoglobulin heavy chain and T cell receptor gamma chain genes].

[Rinsho ketsueki] The Japanese journal of clinical hematology, 2004
We report an unusual case of the 'reverse' variant of follicular lymphoma in which the nodules had central parts that stained dark and cuffs that stained pale. Because diagnosis was difficult relying only on formalin-fixed histopathology, we examined the cell surface markers and karyotype.
Yasufumi, Masaki   +9 more
openaire   +1 more source

Human genes for the immunoglobulin gamma-chain (Gm) allotypes and for the T cell receptor alpha-chain are distantly linked or unlinked.

Experimental and clinical immunogenetics, 1991
Since the genes for two of the T cell receptor (TCR) chains (alpha and delta) and for the immunoglobulin (Ig) heavy chains (alpha, gamma, delta, epsilon and mu) are all on the long arm of human chromosome 14, it is of interest to determine if they are genetically linked and, if so, how strongly.
M J, Sheehy   +3 more
openaire   +1 more source

Studies on fd fragments of human immunoglobulins. III. Immunogenic properties of gamma chains, myeloma fd gamma, and myeloma fd1 alpha.

Scandinavian journal of immunology, 1975
Earlier studies on antisera against Fab of pooled human IgG and IgA myeloma proteins disclosed the presence of class-specific Fd antibodies, the demonstration of which required interaction of heavy and light chains. To extend our knowledge about the antigenic structure of the Fd fragment of human immunoglobulins, antisera were prepared in rabbits ...
J M, Zegers   +2 more
openaire   +1 more source

Human immunoglobulin A receptor (FcalphaRI, CD89) function in transgenic mice requires both FcR gamma chain and CR3 (CD11b/CD18).

Blood, 1999
Even though more immunoglobulin A (IgA) is produced in humans than all other isotypes combined, relatively little is known about receptors that bind the Fc part of IgA. The myeloid IgA receptor, FcalphaRI (CD89), triggers various effector functions in vitro, but its in vivo role remains unclear.
van Egmond, M.   +9 more
openaire   +2 more sources

[Gene rearrangements of immunoglobulin heavy chain (IgH) and T cell receptor gamma chain (TCR gamma) in non-Hodgkin's lymphomas detected by polymerase chain reaction ].

Zhonghua bing li xue za zhi = Chinese journal of pathology, 1994
Gene rearrangement and monoclonality have been detected in non-Hodgkin's lymphomas (NHLs). The semi-nested polymerase chain reaction (PCR) was performed to amplify IgH and the mixed PCR to TCR gamma gene rearrangements. Monoclonal band was observed in 77% of B-cell NHLs with IgH primers and 91% of T-cell NHLs with TCR gamma primers.
J Z, Zhang, L S, Yan
openaire   +1 more source

[Monoclonal analysis of immunoglobulin heavy chain and T-cell receptor gamma chain gene rearrangements in paraffin-embedded tissues from non-Hodgkin lymphoma patients].

Rinsho byori. The Japanese journal of clinical pathology, 2007
Gene rearrangement is an important diagnostic marker of malignant lymphoma, and rearrangements of the immunoglobulin heavy chain (IgH) and T-cell receptor gamma chain (TCRgamma) genes are useful markers for Band T-cell lymphoma, respectively. A polymerase chain reaction (PCR) can be used to analyze clonality in formalin-fixed paraffin-embedded ...
Eisuke, Shiozawa   +5 more
openaire   +1 more source

Heterogeneity of proliferative responses of human B cell precursor acute lymphoblastic leukemia (BCP-ALL) cells to interleukin 7 (IL-7): no correlation with immunoglobulin gene status and expression of IL-7 receptor or IL-2/IL-4/IL-7 receptor common gamma chain genes.

Leukemia, 1995
Interleukin 7 (IL-7) stimulates proliferation of normal human and murine B cell precursor (BCP) cells in a distinct fashion, depending on the stage of maturation of the cells. For instance, the productive rearrangement of the immunoglobulin heavy chain gene has been demonstrated to be essential for the response of BCP cells to IL-7 as the single ...
F J, Smiers   +6 more
openaire   +1 more source

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