Results 221 to 230 of about 225,064 (376)

Epigenetic reprogramming in multiple myeloma—Challenges and opportunities

International Journal of Cancer, EarlyView.
Abstract In cancer, mutational processes act in concert with epigenetic reprogramming to endow malignant cells with hallmark properties that underpin tumorigenesis. Compared with the relatively rigid and slow processes of genetic evolution, the plastic nature of chromatin enables cells to adapt to a changing environment more rapidly.
Subhasree Kumar, Lev M. Kats, Emily Gruber   +2 more
wiley   +1 more source

Analysis of a break in chromosome 14 mapping to the region of the immunoglobulin heavy chain locus. [PDF]

, 1983
Peter S. Linsley, N. Torben Bech‐Hansen, Louis Siminovitch, D W Cox   +3 more
openalex   +1 more source

High-throughput sequencing of the paired human immunoglobulin heavy and light chain repertoire

Nature Biotechnology, 2013
B. Dekosky, G. Ippolito, Ryan P Deschner, Jason J. Lavinder, Y. Wine, Brandon M Rawlings, N. Varadarajan, Claudia Giesecke, T. Dörner, Sarah F Andrews, Patrick C Wilson, Scott P. Hunicke-Smith, C Grant Willson, Andrew D. Ellington, G. Georgiou   +14 more
semanticscholar   +1 more source

Vegetation and environmental dynamics in the central part of the Kola Peninsula during the past 13.3 ka as reflected by ancient plant DNA on sediments from Lake Imandra

Journal of Quaternary Science, EarlyView.
ABSTRACT The first high‐resolution reconstruction of the vegetation and environmental changes during the last ca 13 300 cal a BP in the central part of the Kola Peninsula (NW Russia) was reconstructed based on sedimentary ancient DNA (sedaDNA) metabarcoding on sediment core Co1410 from Lake Imandra.
Anastasia Poliakova, Matthias Lenz, Martin Melles, Grigory Fedorov, Marie K. F. Merkel, Inger G. Alsos   +5 more
wiley   +1 more source

Utility of binding protein fusions to immunoglobulin heavy chain constant regions from mammalian and avian species. [PDF]

J Biol Chem
Zhu N, Smallwood PM, Williams J, Wang Y, Nathans JH.   +4 more
europepmc   +1 more source

Characterization and molecular cloning of the mRNA for the heavy (epsilon) chain of rat immunoglobulin E. [PDF]

, 1982
Lars Hellman, U. Pettersson, H. Bennich
openalex   +1 more source

LRP8 Regulates Lipid Metabolism to Stimulate Malignant Progression and Cisplatin Resistance in Bladder Cancer

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Low‐density lipoprotein receptor‐related protein 8 (LRP8) is a crucial regulator of lipid metabolism and is implicated in the development and treatment of various cancers. However, its role in bladder cancer (BCa) remains unknown. We analyzed LRP8 expression in BCa using the TCGA database and clinical samples. We manipulated LRP8 expression in
Gang‐Feng Wu, Zhen‐Gang Luo, Ke Gao, Yu Ren, Chong Shen, Xiang‐Rong Ying   +5 more
wiley   +1 more source

Genetic diversity of the immunoglobulin heavy chain locus in cohorts of patients affected with SARS-CoV-2. [PDF]

Hum Genomics
Malaspina P, Jodice C, Ciminelli BM, Biancolella M, Colona VL, Latini A, Leonardis F, Rogliani P, Novelli A, Novelli G, Novelletto A.   +10 more
europepmc   +1 more source

Diagnostic Accuracy and Prognostic Relevance of Immunoglobulin Heavy Chain Rearrangement and 18F-FDG-PET/CT Compared With Unilateral Bone Marrow Trephination for Detecting Bone Marrow Involvement in Patients With Diffuse Large B-Cell Lymphoma. [PDF]

J Korean Med Sci, 2022
Kim M, Ahn SY, Ahn JS, Song GY, Jung SH, Lee JJ, Kim HJ, Lee JH, Shin MG, Song SY, Yang DH.   +10 more
europepmc   +1 more source

Effects of immunoglobulin structure on Fc receptor binding: a mouse myeloma variant immunoglobulin with a gamma 2b-gamma 2a hybrid heavy chain having a complete gamma 2a Fc region fails to bind to gamma 2a Fc receptors on mouse macrophages. [PDF]

, 1982
Barbara K. Birshtein, R. Duncan Campbell, Betty Diamond   +2 more
openalex   +1 more source