Results 221 to 230 of about 74,368 (309)

ImmunoTyper-SR: A Novel Computational Approach for Genotyping Immunoglobulin Heavy Chain Variable Genes using Short Read Data

, 2022
Ford M, Hari A, Rodriguez O, Xu J, Lack J, Oguz C, Zhang Y, Weber S, Magglioco M, Barnett J, Xirasagar S, Samuel S, Imberti L, Bonfanti P, Biondi A, Dalgard CL, Chanock S, Rosen L, Holland S, Su H, Notarangelo L, NIAID COVID Consortium, Vishkin U, Watson C, Sahinalp SC.   +24 more
europepmc   +1 more source

Allergic Sensitization to Inhalant Allergens in the Upper Respiratory Tract—the B Cell Side

Allergy, EarlyView.
ABSTRACT Allergic diseases are on the rise worldwide, driven by respiratory epithelial barrier dysfunction that promotes sensitization to inhalant allergens such as pollen, dust mites, pet dander, and fungal spores. These antigens trigger IgE‐mediated immune responses that lead to diseases such as allergic rhinitis (AR) and asthma.
Ola Grimsholm, Mohammed Zghaebi, Bita Hambrecht, Tanja Kalic, Christopher C. Udoye, Rudolf Manz, Barbara Bohle, Katarzyna M. Sitnik, Julia Eckl‐Dorna, Heimo Breiteneder   +9 more
wiley   +1 more source

Recombination may occur in the absence of transcription in the immunoglobulin heavy chain recombination centre. [PDF]

Nucleic Acids Res, 2020
Oudinet C, Braikia FZ, Dauba A, Khamlichi AA.   +3 more
europepmc   +1 more source

The Mouse Immunoglobulin Heavy-Chain Gene Enhancer Contains Sequences That Inhibit Transcription in Vitro in HeLa Cell Extracts

, 1986
Joseph P. Dougherty, Patrick Augereau, Pierre Chambon   +2 more
openalex   +2 more sources

Novel Bispecific Engagers Targeting the CεmX Domain of mIgE‐Expressing Cells

Allergy, EarlyView.
We developed bispecific TCE & NKCE targeting the CεmX domain of mIgE to eliminate IgE‐producing cells. Both constructs demonstrated potent, specific, dose‐dependent cytotoxicity and selective immune activation in vitro. These results highlight their promise as off‐the‐shelf, potentially curative therapeutics for IgE‐associated allergic diseases ...
Constantin Möller, Julia Hambach, Alessa Zoe Schaffrath, Thomas Eden, Sophia Cichutek, Anna Josephine Gebhardt, Natalie Tode, Ronald Maitschke‐Rajasekharan, Philipp Lewe, Sharon Qi, Susanne Witt, Marie Eggers, Nicola M. Tomas, Friedrich Haag, Friedrich Koch‐Nolte, Boris Fehse, Kristoffer Riecken   +16 more
wiley   +1 more source

Prognostic implications of the expression levels of different immunoglobulin heavy chain-encoding RNAs in early breast cancer. [PDF]

NPJ Breast Cancer, 2020
Larsson C, Ehinger A, Winslow S, Leandersson K, Klintman M, Dahl L, Vallon-Christersson J, Häkkinen J, Hegardt C, Manjer J, Saal L, Rydén L, Malmberg M, Borg Å, Loman N.   +14 more
europepmc   +1 more source

<b>DELETION OF IMMUNOGLOBULIN HEAVY CHAIN GENES ACCOMPANIES THE CLASS SWITCH </b><b>REARRANGEMENT </b>

, 1980
Yoshio Yaoita, Tasuku Honjo
openalex   +2 more sources

Chronic Lymphocytic Leukemia (CLL) with Borderline Immunoglobulin Heavy Chain Mutational Status, a Rare Subgroup of CLL with Variable Disease Course. [PDF]

Cancers (Basel)
Angotzi F, Cellini A, Ruocco V, Cavarretta CA, Zatta I, Serafin A, Pravato S, Pagnin E, Bonaldi L, Frezzato F, Facco M, Piazza F, Trentin L, Visentin A.   +13 more
europepmc   +1 more source

How Important Is Corporate Social Responsibility for Corporate Financial Performance?: A Machine Learning Prediction and Model Interpretability Approach

Business Ethics, the Environment &Responsibility, EarlyView.
ABSTRACT Corporate social responsibility (CSR) has become central to corporate strategy, yet its impact on corporate financial performance (CFP) remains debated. Existing literature, which often relies on conventional statistical methods, overlooks the complex, nonlinear interactions between CSR and CFP.
Ephraim Kwashie Thompson, Samuel Buertey, So‐Yeun Kim   +2 more
wiley   +1 more source

Complete detection of FR1 to FR3 primer-based PCR patterns of immunoglobulin heavy chain rearrangement in the BIOMED-2 protocol is associated with poor prognosis in patients with diffuse large B-cell lymphoma. [PDF]

EJHaem
Yabushita T, Shimomura Y, Maruoka H, Katoh D, Yamashita D, Satake H, Hiramoto N, Yoshioka S, Yonetani N, Nishikori M, Morimoto T, Imai Y, Ishikawa T.   +12 more
europepmc   +1 more source