Effects of immunoglobulin structure on Fc receptor binding: a mouse myeloma variant immunoglobulin with a gamma 2b-gamma 2a hybrid heavy chain having a complete gamma 2a Fc region fails to bind to gamma 2a Fc receptors on mouse macrophages. [PDF]
Barbara K. Birshtein+2 more
openalex +1 more source
Diverse Subpopulations of Reactive Astrocytes Following Chronic Toxoplasma Infection
Toxoplasma infection results in distinct astrocyte subpopulations. Chronically labeled reactive astrocytes appear transcriptionally plastic and can regain acute inflammatory responding and naive homeostatic astrocytic gene patterns in the presence of ongoing neuroinflammation.
Zoe A. Figueroa+7 more
wiley +1 more source
Regulation of differential processing of mouse immunoglobulin μ heavy-chain mRNA [PDF]
Naoya Tsurushita+2 more
openalex +1 more source
Organization and Reorganization of Immunoglobulin Heavy-chain Genes
Yuriko Yamawaki-Kataoka+10 more
openaire +3 more sources
Conserved heavy/light contacts and germline preferences revealed by a large-scale analysis of natively paired human antibody sequences and structural data. [PDF]
Dudzic P+11 more
europepmc +1 more source
The chromosome 14 breakpoint in neoplastic B cells with the t(11;14) translocation involves the immunoglobulin heavy chain locus. [PDF]
Jan Erikson+4 more
openalex +1 more source
The t(5;14) chromosomal translocation in a case of acute lymphocytic leukemia joins the interleukin-3 gene to the immunoglobulin heavy chain gene [PDF]
J. Christopher Grimaldi, TC Meeker
openalex +2 more sources
Heavy Chain Deposition Disease in Monoclonal Gammopathy of Renal Significance: A Prodrome of Multiple Myeloma Case and Literature Review. [PDF]
Gnanasampanthan S+3 more
europepmc +1 more source
Epigenetic reprogramming in multiple myeloma—Challenges and opportunities
Abstract In cancer, mutational processes act in concert with epigenetic reprogramming to endow malignant cells with hallmark properties that underpin tumorigenesis. Compared with the relatively rigid and slow processes of genetic evolution, the plastic nature of chromatin enables cells to adapt to a changing environment more rapidly.
Subhasree Kumar+2 more
wiley +1 more source