Results 271 to 280 of about 280,511 (396)

Renal heavy and light chain amyloidosis: A rare case report. [PDF]

Medicine (Baltimore)
Chen B, Wang J, Zang W, Wang C, Li J, Yang R.   +5 more
europepmc   +1 more source

A Kinetic Model of Antigen‐Dependent IgG Oligomerization and Complement Binding

Small Science, EarlyView.
A kinetic model capable of predicting IgG oligomerization, a key step in activating the classical complement pathway (CCP) of the immune system, is presented. The impacts of IgG subclass, concentration, and antigen density are analyzed using advanced biophysical techniques.
Jürgen Strasser, Nikolaus Frischauf, Lukas Schustereder, Andreas Karner, Sieto Bosgra, Aran F. Labrijn, Frank J. Beurskens, Johannes Preiner   +7 more
wiley   +1 more source

Fc-Binding Cyclopeptide Induces Allostery from Fc to Fab: Revealed Through in Silico Structural Analysis to Anti-Phenobarbital Antibody. [PDF]

Foods
Zhou T, Zhang H, Yu X, Pan K, Yao X, Shen X, Lei H.   +6 more
europepmc   +1 more source

Nanoarchitectonics for Pentagon Defects in Carbon: Properties and Catalytic Role in Oxygen Reduction Reaction

Small Methods, EarlyView.
“Pentagon” in carbon framework is focused in this review, although hexagon is standard atomic frames in carbon materials. This review elucidates the fundamental principles governing pentagon‐related activity and offers perspectives on future directions for designing efficient oxygen reduction reaction catalysts based on carbon materials ...
Guoping Chen, Taro Koide, Junji Nakamura, Katsuhiko Ariga   +3 more
wiley   +1 more source

Antigen selection reflected in the subclonal architecture of the B-cell receptor immunoglobulin gene repertoire in splenic marginal zone lymphoma. [PDF]

Hemasphere
Zaragoza-Infante L, Agathangelidis A, Iatrou A, Junet V, Pechlivanis N, Karypidou M, Koletsa T, Karakatsoulis G, Bruscaggin A, Davis Z, Spina V, Verney A, Polychronidou E, Psomopoulos F, Oscier D, Traverse-Glehen A, Papaioannou M, Ghia P, Rossi D, Chatzidimitriou A, Stamatopoulos K.   +20 more
europepmc   +1 more source

Experimental and Computational Insights into the Structural Dynamics of the Fc Fragment of IgG1 Subtype from Biosimilar VEGF‐Trap

Small Structures, EarlyView.
The constant fragment (Fc) of the immunoglobulin G1 (IgG1) subtype is a widely used scaffold for designing advanced therapeutics. Herein, together with the integration of experimental and computational techniques, this study reveals the structural dynamics of the N‐glycan‐bound Fc fragment of IgG1 from VEGF‐Trap, providing a new insight into enhancing ...
Ebru Destan, Engin Turkut, Alper Aldeniz, Jungmin Kang, Takehiko Tosha, Makina Yabashi, Baris Yilmaz, Ahmet Can Timucin, Hiroaki Matsuura, Yoshiaki Kawano, Irfan Cinkaya, Hasan DeMirci   +11 more
wiley   +1 more source

Diagnostic and Therapeutic Aspects of Monoclonal Gammopathies of Renal Significance (MGRS): An Update. [PDF]

Diagnostics (Basel)
Netti GS, Troise D, Rossini M, Catalano V, De Luca F, Khalid J, Camporeale V, Ritrovato F, Infante B, Sanguedolce F, Stallone G, Ranieri E.   +11 more
europepmc   +1 more source

Rearranged immunoglobulin heavy chain variable region (VH) pseudogene that deletes the second complementarity-determining region.

, 1984
Naoki Takahashi, Takafumi Noma, Tasuku Honjo   +2 more
openalex   +1 more source

Feedback inhibition of immunoglobulin gene rearrangement by membrane mu, but not by secreted mu heavy chains. [PDF]

, 1988
J Manz, Kathleen Denis, Owen N. Witte, Ralph L. Brinster, U Storb   +4 more
openalex   +1 more source

Plasma POSTN Derived From Bile Proteome Is a Promising Biomarker for Cholangiocarcinoma With Efficacy Comparable and Complementary to CA19.9

United European Gastroenterology Journal, EarlyView.
ABSTRACT Background Cholangiocarcinoma presents a global health challenge due to its increasing incidence and poor prognosis, primarily resulting from delayed diagnosis. There is an urgent need for a reliable biomarker to enhance early detection. Materials and Methods Patients with cholangiocarcinoma were enrolled into three cohorts: a discovery set (n 
Lichieh Julie Chu, Chia‐Jung Tsai, Chun‐Chun Chien, Yung‐Chin Hsiao, Jau‐Song Yu, Jun‐Yi Tsai, Ta‐Sen Yeh   +6 more
wiley   +1 more source