Immunoglobulin light chain mutational status refines IGHV prognostic value in identifying chronic lymphocytic leukemia patients with early treatment requirement. [PDF]
Nabki J+29 more
europepmc +1 more source
CRISPR/Cas9‐edited tumor‐associated immune cells in cancer immunotherapy
Abstract Immuno‐oncology represents an emerging field that has significantly transformed tumor therapeutics, with immune cells serving as the cellular foundations of cancer immunotherapy. Due to its high efficiency and sensitivity, CRISPR/Cas9 genome editing is a highly promising technique for precise and rapid gene modification.
Yuhui Ma+6 more
wiley +1 more source
Public antibodies: convergent signatures in human humoral immunity against pathogens. [PDF]
Rao VN, Coelho CH.
europepmc +1 more source
Localization of human variable and constant region immunoglobulin heavy chain genes on subtelomeric band q32 of chromosome 14 [PDF]
O. Wesley McBride+5 more
openalex +1 more source
Effecft of co‐doping polyaniline with phosphoric acid and phytic acid on the heat release rate of polyethylene. Abstract Polyolefins, such as polyethylene (PE), are highly flammable and electrically insulative, limiting their applicability. The study explored the flame‐retardancy and electrical conductivity of PE/polyaniline (PE/PANI) nanocomposites ...
Akeem Adisa+4 more
wiley +1 more source
An expandable synthetic library of human paired antibody sequences. [PDF]
Marinov TM+5 more
europepmc +1 more source
3D Mitochondrial Structure in Aging Human Skeletal Muscle: Insights Into MFN‐2‐Mediated Changes
Changes in mitochondrial structure and dynamics during aging provide a mechanism for the development of age‐related sarcopenia, a condition characterized by muscle mass loss. Through the creation of three‐dimensional models of mitochondria from quadriceps muscle tissue taken from old and young humans, a loss in mitochondrial complexity was observed to ...
Estevão Scudese+52 more
wiley +1 more source
Design of orthogonal constant domain interfaces to aid proper heavy/light chain pairing of bispecific antibodies. [PDF]
Barlow KA+13 more
europepmc +1 more source
Immunosenescence Profile Is Associated With Increased Susceptibility to Severe COVID‐19
(A) A previous immunosenescence profile in individuals infected with SARS‐CoV2 creates a permissive environment for progression to severe COVID‐19: higher inflammaging, accumulation of exhausted/senescent T cells, an oligoclonal B‐cell repertoire, and accelerated epigenetic age.
Lucas Haniel A. Ventura+40 more
wiley +1 more source
Functional insights into immunoglobulin superfamily proteins in invertebrate neurobiology and immunity. [PDF]
Li H+11 more
europepmc +1 more source