Characterisation of bovine leukocyte Ig-like receptors [PDF]
Leukocyte Immunoglobulin-like receptors (LILR) are innate immune receptors involved in regulating both innate and adaptive immune functions. LILR show more interspecies conservation than the closely related Killer Ig-like receptors, and homologues have ...
Jones, DC +8 more
core +4 more sources
Using cell-free RNA to identify B- and T-cell clonality for diagnosis and monitoring of B- and T-cell neoplasms. [PDF]
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Albitar A +11 more
europepmc +2 more sources
Immunoglobulin genes and diversity: what we have learned from domestic animals
This review focuses on the diversity of immunoglobulin (Ig) genes and Ig isotypes that are expressed in domestic animals. Four livestock species—cattle, sheep, pigs, and horses—express a full range of Ig heavy chains (IgHs), including μ, δ, γ, ϵ, and α ...
Sun Yi +6 more
doaj +1 more source
Triple immunoglobulin gene knockout transchromosomic cattle: bovine lambda cluster deletion and its effect on fully human polyclonal antibody production. [PDF]
Towards the goal of producing fully human polyclonal antibodies (hpAbs or hIgGs) in transchromosomic (Tc) cattle, we previously reported that Tc cattle carrying a human artificial chromosome (HAC) comprising the entire unrearranged human immunoglobulin ...
Hiroaki Matsushita +7 more
doaj +1 more source
IgA in the horse: cloning of equine polymeric Ig receptor and J chain and characterization of recombinant forms of equine IgA [PDF]
As in other mammals, immunoglobulin A (IgA) in the horse has a key role in immune defense. To better dissect equine IgA function, we isolated complementary DNA (cDNA) clones for equine J chain and polymeric Ig receptor (pIgR).
Wagner, B. +11 more
core +1 more source
The Dynamic of Immunoglobulin IgA and IgM Type Concentration in Milk Colostrum
The aim of the paper was to evaluate the colostrum quality and changes in composition during the first three days postpartum. Researches were carried out on five Romanian Black and White primiparous cows.
George Gabriel Răducan +7 more
doaj
A novel soluble immune-type receptor (SITR) in teleost fish: carp SITR is involved in the nitric oxide-mediated response to a protozoan parasite [PDF]
Background- The innate immune system relies upon a wide range of germ-line encoded receptors including a large number of immunoglobulin superfamily (IgSF) receptors.
Wiegertjes Geert F. +36 more
core +2 more sources
Contributions to the Knowledge of Immunoglobulin Type IgG Concentration Evolution in Colostral Milk
The aim of the paper was to study the evolution of the immunoglobulin type IgG concentrations during the first three days postpartum in Romanian Black and White cows. Researches were carried out on five Romanian Black and White primiparous cows.
George Gabriel Răducan +7 more
doaj
Identification of the ancestral killer immunoglobulin-like receptor gene in primates [PDF]
Background: Killer Immunoglobulin-like Receptors (KIR) are essential immuno- surveillance molecules. They are expressed on natural killer and T cells, and interact with human leukocyte antigens.
Penny Coggill +26 more
core +1 more source
Mechanisms of action of Ig preparations: immunomodulatory and anti-inflammatory effects
Primary immunodeficiency (PIDs) disorders that predispose patients to recurrent infections require immunoglobulin (Ig) replacement therapy. Ig replacement therapy has been defined as beneficial, although the optimal IgG trough level to be maintained over
Andrea eMatucci +2 more
doaj +1 more source

