Results 231 to 240 of about 297,267 (302)

Coordination‐Tuned Iridium Single‐Atom Nanozymes Boost Multienzyme Activity for Colorimetric Sensing

Advanced Science, EarlyView.
Breaking the coordination symmetry of Ir single‐atom sites through asymmetric Ir–N3S1 engineering tailors interfacial electron transfer, oxygen activation, and multienzyme‐like catalytic pathways. Operando spectroscopy and theoretical modeling uncover the atomic‐level origin of activity enhancement, providing a strategy for designing multifunctional ...
Tao Li, Xinyu Zhang, Jiashan Xia, Mengyu Wu, Cong Liu, Yapei Sun, Wanjiang Zhao, Min Qian, Wei Wang, Weixia Duan, Shangcheng Xu   +10 more
wiley   +1 more source

Benchmarking immunoinformatic repertoire assemblies from bulk RNA-seq and PCR-based V(D)J sequencing using PCR-free SMRT RNA sequencing. [PDF]

iScience
Genebrier S, Serra Trinca SB, Dézé O, Cornic M, Pineau M, Tarte K, Cogné M.   +6 more
europepmc   +1 more source

Automation and Active Learning for the Multi‐Objective Optimization of Antibody Formulations

Advanced Science, EarlyView.
Successful antibody formulation necessitates balancing factors such as thermal stability, colloidal stability, and viscosity across a vast excipient design space. This work integrates robotic liquid handling, high‐throughput biophysical characterization, and multi‐objective Bayesian optimization in an iterative closed‐loop Design‐Build‐Test‐Learn cycle.
D. Christopher Radford, Matthew Tamasi, Elena Di Mare, Adam J. Gormley   +3 more
wiley   +1 more source

Induction of subtle blood-brain barrier dysfunction using preclinical diagnostic ultrasound combined with microbubbles. [PDF]

Fluids Barriers CNS
van der Panne SA, Koster IZ, Grootemaat AE, van der Wel NN, Ries MG, de Vries HE, van der Weerd L, Strijkers GJ, Bakker ENTP.   +8 more
europepmc   +1 more source

Rare‐Earth–Sulfur Surface Modification Enables SiC Ceramics for Low‐Frequency Electromagnetic Wave Absorption in Extreme Environments

Advanced Science, EarlyView.
By altering surface chemical bonds to prolong relaxation time and shift absorption to lower frequencies, SiC/rare earth–sulfur (RE─S, RE = La, Ce, Pr, Sm, Gd, Er) materials achieve excellent low‐frequency electromagnetic wave absorption under extreme conditions, offering a new direction for designing high‐performance SiC‐based absorbers.
Zhanming Wu, Xiaojun Zeng, Yu‐Nan Tan, Chi Yu, Nuohua Xie, Yanfeng Gao   +5 more
wiley   +1 more source

Immunoglobulin heavy chain locus duplication in bats. [PDF]

Sci Adv
Pursell T, Reers A, Mikelov A, Kotagiri P, Lam B, Ellison JA, Boyd SD, Frank HK.   +7 more
europepmc   +1 more source

Dual Blockade of LILRB1 and LILRB2 Enhances Antiviral Immune Responses in SIV Infection

Advanced Science, EarlyView.
Dual LILRB1/B2 blockade with mac20G10 reshapes myeloid activation during acute SIV infection by targeting LILRB1 and LILRB2 on myeloid cells. This treatment enhances CD80 expression on selected myeloid subsets and increases plasma IFN‐λ, IL‐8, and IL‐1RA.
Florian Meurisse, Sixtine Coindre, Anne Wijkhuisen, Romain Marlin, Laure Fournier Le Ray, Juliette Pons, Melyssa Yaugel‐Novoa, Véronique Avettand‐Fenoel, Laurent Abi‐Rached, Anne‐Sophie Gallouet, Francis Relouzat, Mael Gourves, Asier Saez‐Cirion, Hisashi Arase, Gerard Zurawski, Sandra Zurawski, Nathalie Dereuddre‐Bosquet, Roger Le Grand, Stéphanie Simon, Olivier Lambotte, Benoit Favier   +20 more
wiley   +1 more source

The Hidden Link: Cryoglobulinemic Membranoproliferative Glomerulonephritis Secondary to Monoclonal Gammopathy of Renal Significance. [PDF]

J Med Cases
Mehyar S, Gomes A, Ghumman HK, Ghumman AK, Eweis N, Pishva S, Kenmoe J.   +6 more
europepmc   +1 more source

GATHeR: graph-based accurate tool for immunoglobulin heavy- and light-chain reconstruction. [PDF]

Nat Commun
Seyedraoufi S, Gornitzka MB, Lossius A.
europepmc   +1 more source

Spatial transcriptomics reveals mechanism of autoimmunity driven by internalised autoantibodies. [PDF]

Ann Rheum Dis
Pinal-Fernandez I, Pak K, Casal-Dominguez M, Muñoz-Braceras S, Wigerblad G, Dell'Orso S, Naz F, Islam S, Gutierrez-Cruz G, Kinder TB, Ogbonnaya-Whittlesey SA, Fernández-Codina A, Giannini M, Ellezam B, Laverny G, Gilbart V, Landon-Cardinal O, Hudson M, Troyanov Y, Randazzo D, Kenea A, Matas-Garcia A, Garrabou G, Aldecoa I, Ailen-Caballero G, Gil-Vila A, Trallero E, Milone M, Liewluck T, Naddaf E, Espinosa G, Simeon-Aznar CP, Guillen-Del-Castillo A, Preusse C, Kleefeld F, Bublitz N, Stenzel W, Meyer A, Pope JE, Selva-O'Callaghan A, Milisenda JC, Mammen AL.   +41 more
europepmc   +1 more source