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Immunoglobulin E (IgE) in patients with severe burns
Burns, 1987The concentrations of immunoglobulin E (IgE) were measured serially in 30 patients with severe burn injury. A characteristic finding was a rapid and dramatic increase of IgE in the serum of all patients, some of whom showed up to 20-fold increases. IgE was also found in considerable amounts in blister fluid and pleural effusions.
V, Polacek +4 more
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A Study of IgE in Immunoglobulin Preparations for Intravenous Administration
Vox Sanguinis, 1986Abstract. We have studied the IgE content of different lots of commercial intravenous IgG preparations used in our day hospital as replacement therapy for patients with agammaglobulinemia. Two enzymatic methods were used: Phadezym and FAST. The average amounts of IgE detected in Endobulin and Sandoglobulin lots were very high with respect to serum ...
R, Paganelli +5 more
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IgE: an immunoglobulin specialized in antigen capture?
Immunology Today, 1990IgE bound to the low-affinity receptor for immunoglobulin E (Fc epsilon R) on antigen-presenting cells (APCs) may permit binding of antigens to APCs prior to their processing and presentation. Here, G. C. Mudde and colleagues argue that the unique characteristics of IgE serological responses together with the distribution of Fc epsilon RII (CD23) on ...
G C, Mudde +4 more
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Allergen-Induced Inflammation and the Role of Immunoglobulin E (IgE)
American Journal of Therapeutics, 2001The prevalence of common allergic disorders such as asthma, allergic rhinitis, and atopic dermatitis has increased significantly in the past 30 years. The impact of these atopic diseases on the patient and the health care system is considerable: Allergic disorders are associated with a high degree of morbidity, which can profoundly impact patient ...
A M, Fendrick, J L, Baldwin
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Function and Structure of Immunoglobulin E (IgE)
1976The function of IgE antibody as mediators in allergic reactions of Type I is explained by their ability to interact both with antigen and with receptor molecules on the membrane of blood basophils and tissue mast cells. However, it is not understood how the interaction of an allergen with cell-bound IgE antibody will induce basophil (mast) cells to ...
H. Bennich +3 more
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Immunoglobulin E (IgE) Blockers (Anti-IgE Therapy)
Abstract Immunoglobulin E (IgE), composed of two light chains and two identical heavy chains, is a key component of many allergic diseases such as asthma. It is produced via communication between B and T cells after exposure to foreign allergens.Eric Reilly, Larry Manders
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Anti-immunoglobulin E (IgE) Therapy
2016The importance of immunoglobulin E (IgE) and allergen-specific IgE in atopic disorders such as asthma, allergic rhinitis, food allergies, and atopic dermatitis is well established. Omalizumab is a humanized, monoclonal antibody that recognizes and binds to the IgE molecule resulting in a rapid and substantial decrease in free IgE in serum.
Jeffrey R. Stokes, Thomas B. Casale
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IgE IN IMMUNOGLOBULIN FOR INTRAVENOUS USE
The Lancet, 1984W, Stephan, H, Dichtelmüller
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Reaginic Activity Associated with Immunoglobulins Other than IgE
The Journal of Immunology, 1970Abstract Absorption studies using antisera to the Fc portion of the IgG molecule isolated from cord sera demonstrated that human reaginic activity belongs to more than one class of immunoglobulin. The data indicated that at least two types of protein carried reaginic activity, one of which was not an IgE immunoglobulin and probably was ...
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