Results 211 to 220 of about 37,394 (238)

Kappa III immunoglobulin light chain origin of localized orbital amyloidosis

Amyloid, 2004
Isolated orbital amyloidosis is a rare condition in which intra-muscular deposits result in proptosis and restriction of eye movement. Previous reports have suggested an immunoglobulin origin of the amyloid fibrils, but this has not been proven biochemically.
Kamran, Hamidi Asl, Juris J, Liepnieks, William R, Nunery, Masahide, Yazaki, Merrill D L, Benson   +4 more
openaire   +2 more sources

The Challenge of Systemic Immunoglobulin Light-Chain Amyloidosis (AL)

2012
The cardiac involvement and associated mortality that occur in systemic AL amyloidosis remain among the most challenging aspects of the systemic amyloid-related diseases. Monoclonal immunoglobulin light chains produced by a clone of plasma cells are usually the cause of symptoms and organ dysfunction via both poorly understood toxic effects of ...
PALLADINI, GIOVANNI, Comenzo, Raymond L.
openaire   +3 more sources

[Treatment strategy for immunoglobulin light chain amyloidosis].

[Rinsho ketsueki] The Japanese journal of clinical hematology, 2021
Systemic AL amyloidosis is a disease wherein amyloid proteins derived from monoclonal immunoglobulin light chains produced by abnormal plasma cells are deposited in the tissues through the whole body and cause organ failure. The treatment aims to minimize treatment-related toxicity and mortality to achieve a deeper and more persistent hematologic ...
openaire   +1 more source

Diagnosis and Therapy of Immunoglobulin Light Chain Amyloidosis (AL Amyloidosis)

2012
Amyloidosis is a group of disorders that have in common the deposition of protein fibrils composed of protofibrils that have a crystallographic β(beta)-pleated sheet structure. Disease results from these proteinaceous deposits in one or more organ systems [1].
Morie A. Gertz, Robert A. Kyle
openaire   +1 more source

Immunoglobulin light-chain amyloidosis mimicking bulbar amyotrophic lateral sclerosis

Amyloid, 2023
Antoine Pegat, Emilien Bernard
openaire   +2 more sources

New criteria for response to treatment in immunoglobulin light chain amyloidosis based on free light chain measurement and cardiac biomarkers: impact on survival outcomes.

Journal of Clinical Oncology, 2012
G. Palladini, A. Dispenzieri, M. Gertz, Shaji K. Kumar, A. Wechalekar, P. Hawkins, S. Schönland, U. Hegenbart, R. Comenzo, E. Kastritis, M. Dimopoulos, A. Jaccard, C. Klersy, G. Merlini   +13 more
semanticscholar   +1 more source

Immunoglobulin Light Chain Amyloidosis

2018
Taxiarchis Kourelis, Morie A. Gertz
openaire   +1 more source

IMMUNOGLOBULIN LIGHT CHAIN AMYLOIDOSIS

2008
Morie A. Gertz, Suzanne R. Hayman
openaire   +1 more source

Overuse of organ biopsies in immunoglobulin light chain amyloidosis (AL): the consequence of failure of early recognition

Annals medicus, 2017
Eli Muchtar, A. Dispenzieri, M. Lacy, F. Buadi, P. Kapoor, S. Hayman, W. Gonsalves, R. Warsame, T. Kourelis, R. Chakraborty, S. Russell, J. Lust, Yi Lin, R. Go, S. Zeldenrust, S. Rajkumar, D. Dingli, N. Leung, R. Kyle, Shaji K. Kumar, M. Gertz   +20 more
semanticscholar   +1 more source

Immunoglobulin Light Chain Amyloidosis (Primary Amyloidosis)

2018
Morie A. Gertz, Francis K. Buadi, Martha Q. Lacy, Suzanne R. Hayman   +3 more
openaire   +1 more source