Results 131 to 140 of about 394,026 (356)
Ku70 Is Required for Late B Cell Development and Immunoglobulin Heavy Chain Class Switching [PDF]
, 1998 Immunoglobulin (Ig) heavy chain (HC) class switch recombination (CSR) is a late B cell process that involves intrachromosomal DNA rearrangement.
Alt, Frederick W. +7 more
core +2 more sources
Advanced Healthcare Materials, Volume 14, Issue 10, April 15, 2025.Aptamer (A) conjugated gold nanorods (B) for the recognition of bladder cancer cells expressing the integrin α5β1 (C) and the visualization of the targeted GNRs@Chit‐Apt‐Itg by photoacoustic imaging at the surface of the orthotopic bladder cancer in the preclinical model (D).
Chiara Venegoni +15 more
wiley +1 more source
Journal of Applied Hematology, 2015 Protein and immunofixation electrophoresis are the laboratory backbone assays for testing multiple myeloma (MM) and related plasma cell proliferative diseases.
Juana Jiménez Jiménez +3 more
doaj +1 more source
Crowding-Regulated Binding of Divalent Biomolecules [PDF]
Phys. Rev. Lett. 130, 258401 (2023)Macromolecular crowding affects biophysical processes as diverse as diffusion, gene expression, cell growth, and senescence. Yet, there is no comprehensive understanding of how crowding affects reactions, particularly multivalent binding. Herein, we use scaled particle theory and develop a molecular simulation method to investigate the binding of ...
arxiv +1 more source
Complete analysis of the B-cell response to a protein antigen, from in vivo germinal centre formation to 3-D modelling of affinity maturation [PDF]
, 2003 Somatic hypermutation of immunoglobulin variable region genes occurs within germinal centres (GCs) and is the process responsible for affinity maturation of antibodies during an immune response.
Batista FD +36 more
core +3 more sources
Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.The top‐performing lipid nanoparticle, incorporating a novel ionizable lipid derived from vitamin B5, demonstrates high mRNA transfection efficiency, low toxicity, favorable stability, targeted delivery to lymphoid tissues, and high immunogenicity, showing promise as a carrier for mRNA vaccines for infectious diseases and cancer.
Soyeon Yoo +11 more
wiley +1 more source
A Low-temperature 1H NMR Study of H2O and D2O Associated Competitively with Immunoglobulin G in Solution [PDF]
arXiv, 2007 An approach has been proposed to characterize the competitive association of D2O and to study the heterogeneity of hydration water adsorbed by the protein, immunoglobulin G, using methodology for determining of non-freezing water in mixed H2O-D2O protein solutions by low-temperature 1H NMR technique. Direct data on the numbers of deuteriums adsorbed by
arxiv
Humoral and Secretory Immunoglobulins of the Sheepshead, Archosargus probatocephalus, A Marine Teleost [PDF]
, 1980 The sheepshead has two readily isolatable humoral immunoglobulins, a 16S tetrameric form and a 6S monomeric form. The 16S tetrameric form is composed of two subpopulations, one being a disulfide linked form (~700,000 daltons) and the other a ...
Lobb, Craig J.
core +1 more source
A mouse renin promoter containing the conserved decanucleotide element binds the same B-cell factors as an authentic immunoglobulin heavy chain promoter [PDF]
, 1987 A mouse renin-1 gene promoter fragment, normally inactive in B-cells, becomes a potent promoter in these cells after insertion of the highly conserved decanucleotide (dc/cd sequence) of immunoglobulin heavy and light chain promoters [(1987) EMBO J.
Doyen, Noelle +3 more
core +1 more source
Advanced Healthcare Materials, EarlyView.This study reports a novel strategy for preparing a biocompatible adhesive hydrogel crosslinked with a muscle tissue‐derived extracellular matrix (MEM) for in situ muscle regeneration. As a natural crosslinker, MEM not only mediates combinatorial polymer networks but also stimulates satellite cells to induce a cell‐free therapeutic solution.
Eun Je Jeon +6 more
wiley +1 more source