Results 91 to 100 of about 34,385 (232)
A Case of Severe Cholestasis due to Hepatic AL Amyloidosis
GE: Portuguese Journal of Gastroenterology, 2019 Introduction: Immunoglobulin light chain-associated amyloidosis results from extracellular tissue deposition of fibril-forming monoclonal immunoglobulin light chains, secreted by a clone of plasma cells.
Teresa Dias +5 more
doaj +1 more source
Critical Management Strategies for Cardiovascular Involvementin Light Chain Amyloidosis
罕见病研究, 2023 Light chain amyloidosis (AL) is a kind of rare disease. The misfolding of the light chain of monoclonal immunoglobulin forms amyloid substances and deposit in different tissues and organs, resulting in organ dysfunction.
SHI Yunjing, JIN Wei
doaj +1 more source
Mandibular destructive radiolucent lesion: the first sign of multiple myeloma [PDF]
, 2016 The occurrence of a mandibular lesion as the first sign of multiple myeloma (MM) is uncommon. This report describes a case of MM diagnosed because of a mandibular lesion.
Fregnani, Eduardo Rodrigues +5 more
core +2 more sources
Barriers to Small Molecule Drug Discovery for Systemic Amyloidosis
Molecules, 2021 Inhibition of amyloid fibril formation could benefit patients with systemic amyloidosis. In this group of diseases, deposition of amyloid fibrils derived from normally soluble proteins leads to progressive tissue damage and organ failure.
Gareth J. Morgan
doaj +1 more source
Acute kidney injury on chronic kidney disease: From congestive heart failure to light chain deposition disease and cast nephropathy in multiple myeloma [PDF]
, 2019 Acute on chronic renal failure is a common but notably broad diagnosis. We present a 64-year-old man with a history of diastolic heart failure and chronic kidney disease, admitted for an elevated creatinine.
Cheng, Steven +3 more
core +1 more source
Two cases of monoclonal nodular pulmonary amyloidosis and review of the literature [PDF]
, 2016 Nodular pulmonary amyloidosis (NPA) is an uncommon pathology of insoluble protein depositing in pulmonary parenchyma. This localized pulmonary form of amyloidosis is most often found to contain combinations of kappa and lambda immunoglobulin light chain ...
Endicott, Kendal +4 more
core +2 more sources
European Journal of Heart Failure, EarlyView.Proposed algorithm to screen for transthyretin cardiac amyloidosis (ATTR‐CA). AL‐CA, immunoglobulin light‐chain cardiac amyloidosis; AMYLI, AMYLoidosis Index; AUC, area under the curve; IWT, increased wall thickness; LVEF, left ventricular ejection fraction; PYP, pyrophosphate.
Giovanni Battista Bonfioli +11 more
wiley +1 more source
Annals of Internal Medicine: Clinical CasesLight chain (AL) amyloidosis involves deposition of monoclonal immunoglobulin light chain-derived amyloid fibrils, whereas ATTR amyloidosis involves deposition of insoluble antiparallel beta-pleated protein within tissues, leading to organ-specific ...
Robert A. Churchill, Andrew Rosenbaum
doaj +1 more source
Journal of Medical Science, 2016 Amyloidosis is a heterogeneous group of disorders associated with pathological deposition of amyloid. We can recognize two major categories of amyloidosis: primary (AL) and secondary (AA) type.
Agnieszka Danuta Gaczkowska +2 more
doaj +1 more source
ATTR Variant Amyloidosis in Patients with Dysphagia
Surgeries, 2023 Amyloidosis is a rare disease characterized by the accumulation of misfolded extracellular proteins in various organs. Over 30 precursor proteins have been identified that can form amyloid deposits in different parts of the body.
Christina Hui Lee Ng +2 more
doaj +1 more source