Results 121 to 130 of about 34,385 (232)

Pulmonary light chain deposition disease: Case series and review of the literature

Radiology Case Reports
Pulmonary light chain deposition disease is a rare entity characterized by immunoglobulin deposition within the lung parenchyma with pathologic features distinct from pulmonary amyloidosis.
Tomas V. Gonzalez, MD, Anja C. Roden, MD, Brian J. Bartholmai, MD, Rebecca M. Lindell, MD   +3 more
doaj   +1 more source

High prevalence of wild‐type transthyretin cardiac amyloidosis in older adults with carpal tunnel syndrome, heart failure or increased left ventricular mass: The CAPTURE study

European Journal of Heart Failure, EarlyView.
Alberto Aimo, Giuseppe Vergaro, Maria Concetta Pastore, Daniela Tomasoni, Vincenzo Castiglione, Riccardo Saro, Elisa Zaro, Antonio Maria Sammartino, Elisa Giacomin, Matteo Serenelli, Alberto Cipriani, Aldostefano Porcari, Andrea Di Lenarda, Marco Metra, Gianfranco Sinagra, Matteo Cameli, Marco Merlo, Michele Emdin   +17 more
wiley   +1 more source

Elevation of Immunoglobulin Free Light Chain and BAFF Levels Associated With Immune Activation Predicts Survival Rates in Chronic Liver Disease

Hepatology Research, Volume 55, Issue 11, Page 1531-1540, November 2025.
ABSTRACT Aims Elevated serum free light chain (FLC) and B‐cell activating factor (BAFF) levels have been reported to be associated with B‐cell activation and to serve as biomarkers reflecting disease severity in various diseases. However, limited investigation has been conducted in the context of chronic liver disease (CLD), and the aim of this study ...
Motoh Iwasa, Akiko Eguchi, Yasuyuki Tamai, Ryuta Shigefuku, Hideaki Tanaka, Ryo Nakagawa, Mina Tempaku, Yoshinao Kobayashi, Hayato Nakagawa   +8 more
wiley   +1 more source

Candidate genes of Waldenström’s macroglobulinemia: current evidence and research [PDF]

, 2014
Waldenström’s macroglobulinemia (WM) is a relatively uncommon, indolent malignancy of immunoglobulin M-producing B cells. The World Health Organization classifies it as a lymphoplasmacytic lymphoma and patients typically present with anemia ...
Bianchi, Giada, Ghobrial, Irene, Kumar, Shaji, Roccaro, Aldo, Rossi, Giuseppe, Sacco, Antonio   +5 more
core   +1 more source

Senile Systemic Amyloidosis: Clinical Features at Presentation and Outcome [PDF]

, 2013
Background Cardiac amyloidosis is a fatal disease whose prognosis and treatment rely on identification of the amyloid type. In our aging population transthyretin amyloidosis (ATTRwt) is common and must be differentiated from other amyloid types.
Banypersad, SM, Dungu, J, Gibbs, SD, Gilbertson, JA, Gillmore, JD, Hawkins, PN, Lachmann, HJ, McCarthy, CA, Petrie, A, Pinney, JH, Rowczenio, D, Sattianayagam, P, Venner, CP, Wassef, N, Wechalekar, A, Whelan, CJ   +15 more
core   +1 more source

Current management of non‐amyloidosis monoclonal gammopathy of renal significance: Clinical features, treatment selections, responses and renal outcomes

British Journal of Haematology, EarlyView.
Daniel Cancilla, Hanny Sawaf, Xuefei Jia, Danai Dima, Ali Mehdi, Hira Shaikh, Beth Faiman, Faiz Anwer, Sandra Mazzoni, Diana Basali, Jack Khouri, Christy Samaras, Jason Valent, Shahzad Raza, Louis Williams   +14 more
wiley   +1 more source

Rapid hematologic responses improve outcomes in patients with very advanced (stage IIIb) cardiac immunoglobulin light chain amyloidosis

Haematologica, 2018
Systemic AL amyloidosis (AL) is caused by deposition of misfolded immunoglobulin light chains, leading to potentially catastrophic visceral dysfunction.[1][1] Outcomes are heterogeneous, but cardiac involvement is a key survival predictor.
R. Manwani, Darren Foard, S. Mahmood, S. Sachchithanantham, T. Lane, C. Quarta, T. Youngstein, T. Rezk, H. Lachmann, J. Gillmore, M. Fontana, C. Whelan, P. Hawkins, A. Wechalekar   +13 more
semanticscholar   +1 more source

Multiple Myeloma and AL Amyloidosis [PDF]

, 2016
O mieloma múltiplo e a amiloidose de cadeias leves (AL) de imunoglobulina são doenças proliferativas plasmocitárias incuráveis que raramente coexistem. Cerca de 10 a 15% dos doentes com mieloma múltiplo desenvolvem amiloidose AL clinicamente sintomática,
Alcatrão, M, Bravo, A, Estrada, H, Gaspar, A, Margarido, E, Neves, C   +5 more
core  

Folding of a single domain protein entering the endoplasmic reticulum precedes disulfide formation [PDF]

, 2017
The relationship between protein synthesis, folding and disulfide formation within the endoplasmic reticulum (ER) is poorly understood. Previous studies have suggested pre-existing disulfide links are absolutely required to allow protein folding and ...
Bulleid, Neil J., Pringle, Marie Anne, Robinson, Philip J., Woolhead, Cheryl A.   +3 more
core   +1 more source

Localized AL amyloidosis: A suicidal neoplasm? [PDF]

, 2012
Although AL amyloidosis usually is a systemic disease, strictly localized AL deposits are not exceptionally rare. Such case reports form a considerable body of published articles.
Westermark, Per
core   +2 more sources